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Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice. Aloisi E, Le Corf K, Dupuis J, Zhang P, Ginger M, Labrousse V, Spatuzza M, Georg Haberl M, Costa L, Shigemoto R, Tappe-Theodor A, Drago F, Vincenzo Piazza P, Mulle C, Groc L, Ciranna L, Catania MV, Frick A. Nat…

J.B. Sibarita, A. Beghin et al. in Nature Methods

Localization-based super-resolution imaging meets high-content screening. Beghin A, Kechkar A, Butler C, Levet F, Cabillic M, Rossier O, Giannone G, Galland R, Choquet D, Sibarita JB. Nat Methods. 2017 Oct 30. doi: 10.1038/nmeth.4486. [Epub ahead of print] Jean-Baptiste Sibarita team leader et Anne Beghin: Quantitative Imaging of the Cell Institut Interdisciplinaire de Neurosciences / Bordeaux Neurocampus…

E. Aloisi, A. Frick et al. in Nature Communication

Le 21 novembre 2017 Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice. Aloisi E, Le Corf K, Dupuis J, Zhang P, Ginger M, Labrousse V, Spatuzza M, Georg Haberl M, Costa L, Shigemoto R, Tappe-Theodor A, Drago F, Vincenzo Piazza P, Mulle C, Groc L, Ciranna L, Catania MV,…

IMN and GIN in Nature Communication

The challenge of mapping the human connectome based on diffusion tractography. Nature Communications, doi:10.1038/s41467-017-01285-x. Maier-Hein, K. H., Neher, P. F., Houde, J.-C., Côté, M.-A., Garyfallidis, E., Zhong, J., et al. (2017). The challenge of mapping the human connectome based on diffusion tractography. Nature Communications, 1–13. http://doi.org/10.1038/s41467-017-01285-x   > Sorry, in french! Cartographier le  « connectome » humain requiert d’identifier les…

Joana Ferreira and Thomas Papouin ineLife

Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses. Ferreira JS, Papouin T, Ladépêche L, Yao A, Langlais VC, Bouchet D, Dulong J, Mothet JP, Sacchi S, Pollegioni L, Paoletti P, Oliet SHR, Groc L. Elife. 2017 Jun 9;6. pii: e25492. doi: 10.7554/eLife.25492. Laurent Groc: Interdisciplinary Institute for NeuroSciences, CNRS , Bordeaux, France Stéphane Oliet:  Neurocentre Magendie, Inserm,…

Christophe Mulle et al. in Nat Rev Neurosci.

Operation and plasticity of hippocampal CA3 circuits: implications for memory encoding/ Rebola N, Carta M, Mulle C.  Nat Rev Neurosci. 2017 Apr;18(4):208-220. Review. The CA3 region of the hippocampus is important for rapid encoding of memory. Computational theories have proposed specific roles in hippocampal function and memory for the sparse inputs from the dentate gyrus to  CA3…

How Hyperarousal and Sleep Reactivity Are Represented in Different Adult Age Groups: Results from a Large Cohort Study on Insomnia.

Altena E, Chen IY, Daviaux Y, Ivers H, Philip P, Morin CM. How Hyperarousal and Sleep Reactivity Are Represented in Different Adult Age Groups: Results from a Large Cohort Study on Insomnia. Brain Sci. 2017 Apr 14;7(4). pii: E41. Abstract Hyperarousal is a 24-h state of elevated cognitive and physiological activation, and is a core…

Optimized labeling of membrane proteins for applications to super-resolution imaging in confined cellular environments using monomeric streptavidin.

Chamma I, Rossier O, Giannone G, Thoumine O, Sainlos M. Optimized labeling of membrane proteins for applications to super-resolution imaging in confined cellular environments using monomeric streptavidin. Nat Protoc. 2017 Apr;12(4):748-763 Abstract Recent progress in super-resolution imaging (SRI) has created a strong need to improve protein labeling with probes of small size that minimize the target-to-label…

D.Perrais, M. Rosendale inCell Reports

February 23rd, 2017 Rosendale M, Jullié D, Choquet D, Perrais D. (2017) Spatial and temporal regulation of receptor endocytosis in neuronal dendrites revealed by imaging of single vesicle formation. Cell Reports, Feb 21 David Perrais  /IINS Bordeaux / Nano-scale organization, dynamics of synaptic proteins and membrane trafficking. Morgane Rosendale: Brain Research Institute RIKEN, Japon  …

Lucile Capuron, Julie Lasselin et al. in Brain Behav Immun.

Low-grade inflammation is a major contributor of impaired attentional set shifting in obese subjects. Lasselin J, Magne E, Beau C, Aubert A, Dexpert S, Carrez J, Layé S, Forestier D, Ledaguenel P, Capuron L. Brain Behav Immun. 2016 May 17. pii: S0889-1591(16)30122-2. doi: 10.1016/j.bbi.2016.05.013. [Epub ahead of print] PMID:27223095 Historique : Obesity represents currently a major public health concern. Not…