Sylvie Vancassel

Scientific articles

• Saffron extract interferes with lipopolysaccharide-induced brain activation of the kynurenine pathway and impairment of monoamine neurotransmission in mice
  Camille Monchaux de Oliveira, Jennifer Morael, Alexandrine Guille, Camille Amadieu, Sylvie Vancassel, David Gaudout, Lucile Capuron, Line Pourtau, Nathalie Castanon.
  Front. Nutr.. 2023-10-05. 10
  10.3389/fnut.2023.1267839
• Tetrahydrobiopterin modulates the behavioral neuroinflammatory response to an LPS challenge in mice
  S. Vancassel, H. Fanet, N. Castanon, C. Monchaux De Oliveira, S. Cussotto, L. Capuron.
  Brain, Behavior, and Immunity. 2022-10-01. 105 : 139-148.
  10.1016/j.bbi.2022.06.016
• Preventive Vitamin A Supplementation Improves Striatal Function in 6-Hydroxydopamine Hemiparkinsonian Rats
  Anaïs Marie, Julien Leroy, Morgane Darricau, Serge Alfos, Veronique De Smedt-Peyrusse, Emmanuel Richard, Sylvie Vancassel, Clementine Bosch-Bouju.
  Front. Nutr.. 2022-02-01. 9
  10.3389/fnut.2022.811843
• Prevention of Stress-Induced Depressive-like Behavior by Saffron Extract Is Associated with Modulation of Kynurenine Pathway and Monoamine Neurotransmission
  Camille Monchaux De Oliveira, Véronique De Smedt-Peyrusse, Jennifer Morael, Sylvie Vancassel, Lucile Capuron, David Gaudout, Line Pourtau, Nathalie Castanon.
  Pharmaceutics. 2021-12-14. 13(12) : 2155.
  10.3390/pharmaceutics13122155
• A new experimental design to study inflammation-related versus non-inflammation-related depression in mice
  Pierre Cardinal, Camille Monchaux de Oliveira, Julie Sauvant, Aline Foury, Muriel Darnaudéry, Sylvie Vancassel, Nathalie Castanon, Lucile Capuron.
  J Neuroinflammation. 2021-12-01. 18(1)
  10.1186/s12974-021-02330-9
• Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry
  H. Fanet, L. Capuron, N. Castanon, F. Calon, S. Vancassel.
  CN. 2021-04-29. 19(5) : 591-609.
  10.2174/1570159x18666200729103529
• Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission
  Camille Monchaux De Oliveira, Line Pourtau, Sylvie Vancassel, Camille Pouchieu, Lucile Capuron, David Gaudout, Nathalie Castanon.
  Nutrients. 2021-03-11. 13(3) : 904.
  10.3390/nu13030904
• Tetrahydrobiopterin improves recognition memory in the triple-transgenic mouse model of Alzheimer’s disease, without altering amyloid-β and tau pathologies
  Hortense Fanet, Marine Tournissac, Manon Leclerc, Vicky Caron, Cyntia Tremblay, Sylvie Vancassel, Frédéric Calon.
  JAD. 2021-01-19. 79(2) : 709-727.
  10.3233/JAD-200637
• Inflammatory Bases of Neuropsychiatric Symptom Domains: Mechanisms and Specificity.
  Bruno Aouizerate, Sylvie Vancassel, Nathalie Castanon, Lucile Capuron.
  Immuno-Psychiatry. 2021-01-01. : 335-353.
  10.1007/978-3-030-71229-7_20
• The gut microbiota metabolite indole increases emotional responses and adrenal medulla activity in chronically stressed male mice
  Hayatte-Dounia Mir, Alexandre Milman, Magali Monnoye, Véronique Douard, Catherine Philippe, Agnès Aubert, Nathalie Castanon, Sylvie Vancassel, Nathalie C. Guérineau, Laurent Naudon, Sylvie Rabot.
  Psychoneuroendocrinology. 2020-09-01. 119 : 104750.
  10.1016/j.psyneuen.2020.104750
• Causal Link between n-3 Polyunsaturated Fatty Acid Deficiency and Motivation Deficits.
  Fabien Ducrocq, Roman Walle, Andrea Contini, Asma Oummadi, Baptiste Caraballo, Suzanne van der Veldt, Marie-Lou Boyer, Frank Aby, Tarson Tolentino-Cortez, Jean-Christophe Helbling, Lucy Martine, Stéphane Grégoire, Stéphanie Cabaret, Sylvie Vancassel, Sophie Layé, Jing Xuan Kang, Xavier Fioramonti, Olivier Berdeaux, Gabriel Barreda-Gómez, Elodie Masson, Guillaume Ferreira, David W.L. Ma, Clementine Bosch-Bouju, Véronique De Smedt-Peyrusse, Pierre Trifilieff.
  Cell Metabolism. 2020-04-01. 31(4) : 755-772.e7.
  10.1016/j.cmet.2020.02.012
• Decrease in Operant Responding Under Obesogenic Diet Exposure is not Related to Deficits in Incentive or Hedonic Processes.
  Fabien Ducrocq, Alexia Hyde, Hortense Fanet, Asma Oummadi, Roman Walle, Véronique De Smedt-Peyrusse, Sophie Layé, Guillaume Ferreira, Pierre Trifilieff, Sylvie Vancassel.
  Obesity. 2018-12-30. 27(2) : 255-263.
  10.1002/oby.22358
• Dietary intake of branched-chain amino acids in a mouse model of Alzheimer’s disease: Effects on survival, behavior, and neuropathology
  Marine Tournissac, Milene Vandal, Cyntia Tremblay, Philippe Bourassa, Sylvie Vancassel, Vincent Emond, Anne Gangloff, Frederic Calon.
  A&D Transl Res & Clin Interv. 2018-01-01. 4(1) : 677-687.
  10.1016/j.trci.2018.10.005
• Docosahexaenoic acid (DHA) prevents corticosterone-induced changes in astrocyte morphology and function
  Gaëlle Champeil‐Potokar, Marie Hennebelle, Alizée Latour, Sylvie Vancassel, Isabelle Denis.
  Journal of Neurochemistry. 2016-01-29. 136(6) : 1155-1167.
  10.1111/jnc.13510
• Omega-3 polyunsaturated fatty acids and brain aging
  Isabelle Denis, Brigitte Potier, Christine Heberden, Sylvie Vancassel.
  Current Opinion in Clinical Nutrition and Metabolic Care. 2015-03-01. 18(2) : 139-146.
  10.1097/MCO.0000000000000141
• Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats
  Michèle Crumeyrolle-Arias, Mathilde Jaglin, Aurélia Bruneau, Sylvie Vancassel, Ana Cardona, Valérie Daugé, Laurent Naudon, Sylvie Rabot.
  Psychoneuroendocrinology. 2014-04-01. 42 : 207-217.
  10.1016/j.psyneuen.2014.01.014
• Omega-3 polyunsaturated fatty acids and chronic stress-induced modulations of glutamatergic neurotransmission in the hippocampus
  Marie Hennebelle, Gaëlle Champeil-Potokar, Monique Lavialle, Sylvie Vancassel, Isabelle Denis.
  Nutr Rev. 2014-01-13. 72(2) : 99-112.
  10.1111/nure.12088
• Omega-3 fatty acids and brain resistance to ageing and stress: body of evidence and possible mechanisms
  I. Denis, B. Potier, S. Vancassel, C. Heberden, M. Lavialle.
  Ageing Research Reviews. 2013-03-01. 12(2) : 579-594.
  10.1016/j.arr.2013.01.007
• Omega-3 fatty acids deficiency aggravates glutamatergic synapse and astroglial aging in the rat hippocampal CA1
  Alizée Latour, Barbara Grintal, Gaelle Champeil‐Potokar, Marie Hennebelle, Monique Lavialle, Patrick Dutar, Brigitte Potier, Jean‐Marie Billard, Sylvie Vancassel, Isabelle Denis.
  Aging Cell. 2012-11-27. 12(1) : 76-84.
  10.1111/acel.12026
• Influence of Omega-3 Fatty acid status on the way rats adapt to chronic restraint stress.
  Marie Hennebelle, Laure Balasse, Alizée Latour, Gaelle Champeil-Potokar, Stéphanie Denis, Monique Lavialle, Pascale Gisquet-Verrier, Isabelle Denis, Sylvie Vancassel.
  PLoS ONE. 2012-07-30. 7(7) : e42142.
  10.1371/journal.pone.0042142
• Dietary n-3 polyunsaturated fatty acid deprivation together with early maternal separation increases anxiety and vulnerability to stress in adult rats.
  Géraldine Mathieu, Catherine Oualian, Isabelle Denis, Monique Lavialle, Pascale Gisquet-Verrier, Sylvie Vancassel.
  Prostaglandins, Leukotrienes and Essential Fatty Acids. 2011-09-01. 85(3-4) : 129-136.
  10.1016/j.plefa.2011.07.001
• Reciprocal influence of stress and n-3 polyunsaturated fatty acids (PUFA) status on astrocyte function
  .
  Glia. 2011-08-17. 59(S1)
  10.1002/glia.21210
• Acides gras polyinsaturés n-3 (oméga 3) et cerveau
  I. Denis, C. Heberden, S. Vancassel, M. Lavialle.
  Med. Nutr.. 2011-01-01. 47(2) : 17-28.
  10.1051/mnut/201120004
• Involvement of omega-3 fatty acids in emotional responses and hyperactive symptoms
  Monique Lavialle, Isabelle Denis, Philippe Guesnet, Sylvie Vancassel.
  The Journal of Nutritional Biochemistry. 2010-10-01. 21(10) : 899-905.
  10.1016/j.jnutbio.2009.12.005
• DHA enhances the noradrenaline release by SH-SY5Y cells
  Mathieu Géraldine, Denis Stéphanie, Langelier Bénédicte, Denis Isabelle, Lavialle Monique, Vancassel Sylvie.
  Neurochemistry International. 2010-01-01. 56(1) : 94-100.
  10.1016/j.neuint.2009.09.006
• Inhibition of astroglial glutamate transport by polyunsaturated fatty acids: evidence for a signalling role of docosahexaenoic acid
  Barbara Grintal, Gaëlle Champeil-Potokar, Monique Lavialle, Sylvie Vancassel, Sylvie Breton, Isabelle Denis.
  Neurochemistry International. 2009-07-01. 54(8) : 535-543.
  10.1016/j.neuint.2009.02.018
• Synergistic effects of stress and omega-3 fatty acid deprivation on emotional response and brain lipid composition in adult rats
  G. Mathieu, S. Denis, M. Lavialle, S. Vancassel.
  Prostaglandins, Leukotrienes and Essential Fatty Acids. 2008-06-01. 78(6) : 391-401.
  10.1016/j.plefa.2008.05.003
• N-3 polyunsaturated fatty acid supplementation reverses stress-induced modifications on brain monoamine levels in mice
  S. Vancassel, S. Leman, L. Hanonick, S. Denis, J. Roger, M. Nollet, S. Bodard, I. Kousignian, C. Belzung, S. Chalon.
  Journal of Lipid Research. 2008-02-01. 49(2) : 340-348.
  10.1194/jlr.M700328-JLR200
• Hyperactivity in the rat is associated with spontaneous low level of n-3 polyunsaturated fatty acids in the frontal cortex
  S. Vancassel, C. Blondeau, S. Lallemand, M. Cador, A. Linard, M. Lavialle, F. Dellu-Hagedorn.
  Behavioural Brain Research. 2007-06-01. 180(2) : 119-126.
  10.1016/j.bbr.2007.02.032
• DHA involvement in neurotransmission process
  Sylvie Vancassel, Sabah Aïd, Isabelle Denis, Philippe Guesnet, Monique Lavialle.
  OCL. 2007-05-01. 14(3-4) : 164-170.
  10.1051/ocl.2007.0116
• Le DHA dans la neurotransmission
  Monique Lavialle, Gaëlle Champeil-Potokar, Isabelle Denis, Philippe Guesnet, Fabien Pifferi, Sylvie Vancassel.
  OCL. 2007-01-01. 14(1) : 11-15.
  10.1051/ocl.2007.0099
• Cerebral Asymmetry and Behavioral Lateralization in Rats Chronically Lacking n-3 Polyunsaturated Fatty Acids
  Sylvie Vancassel, Sabah Aïd, Fabien Pifferi, Elise Morice, Marika Nosten-Bertrand, Sylvie Chalon, Monique Lavialle.
  Biological Psychiatry. 2005-11-01. 58(10) : 805-811.
  10.1016/j.biopsych.2005.04.045
• Cerebral Asymmetry and Behavioral Lateralization in Rats Chronically Lacking n-3 Polyunsaturated Fatty Acids
  Sylvie Vancassel, Sabah Aïd, Fabien Pifferi, Elise Morice, Marika Nosten-Bertrand, Sylvie Chalon, Monique Lavialle.
  Biological Psychiatry. 2005-11-01. 58(10) : 805-811.
  10.1016/j.biopsych.2005.04.045
• (n-3) Polyunsaturated Fatty Acid Deficiency Reduces the Expression of Both Isoforms of the Brain Glucose Transporter GLUT1 in Rats
  Fabien Pifferi, Françoise Roux, Bénédicte Langelier, Jean-Marc Alessandri, Sylvie Vancassel, Mélanie Jouin, Monique Lavialle, Philippe Guesnet.
  The Journal of Nutrition. 2005-09-01. 135(9) : 2241-2246.
  10.1093/jn/135.9.2241
• Omega 3 fatty acids and functions of the central nervous system
  Philippe Guesnet, Jean-Marc Alessandri, Sylvie Vancassel, Isabelle Denis, Monique Lavialle.
  Nutrition Clinique et Métabolisme. 2005-09-01. 19(3) : 131-134.
  10.1016/J.NUPAR.2005.06.004
• Polyunsaturated fatty acids in the central nervous system: evolution of concepts and nutritional implications throughout life
  Jean-Marc Alessandri, Philippe Guesnet, Sylvie Vancassel, Pierre Astorg, Isabelle Denis, Bénédicte Langelier, Sabah Aïd, Carine Poumès-Ballihaut, Gaëlle Champeil-Potokar, Monique Lavialle.
  Reprod. Nutr. Dev.. 2004-11-01. 44(6) : 509-538.
  10.1051/rnd:2004063
• Analysis of the 2nd symposium “Anomalies of fatty acids, ageing and degenerating pathologies”
  Philippe Guesnet, Jean-Marc Alessandri, Sylvie Vancassel, Nicolas Zamaria.
  Reprod. Nutr. Dev.. 2004-05-01. 44(3) : 263-271.
  10.1051/rnd:2004031
• Serotoninergic neurotransmission is affected by n-3 polyunsaturated fatty acids in the rat
  Ercem Kodas, Laurent Galineau, Sylvie Bodard, Sylvie Vancassel, Denis Guilloteau, Jean‐Claude Besnard, Sylvie Chalon.
  Journal of Neurochemistry. 2004-03-30. 89(3) : 695-702.
  10.1111/j.1471-4159.2004.02401.x
• Oméga 3 et neurotransmission cérébrale
  Sylvie Vancassel.
  OCL. 2004-01-01. 11(1) : 58-65.
  10.1051/ocl.2004.0058
• Effect of a diet-induced n-3 PUFA depletion on cholinergic parameters in the rat hippocampus
  Sabah Aïd, Sylvie Vancassel, Carine Poumès-Ballihaut, Sylvie Chalon, Philippe Guesnet, Monique Lavialle.
  Journal of Lipid Research. 2003-08-01. 44(8) : 1545-1551.
  10.1194/jlr.M300079-JLR200
• Reversibility of n-3 fatty acid deficiency-induced changes in dopaminergic neurotransmission in rats: critical role of developmental stage
  Ercem Kodas, Sylvie Vancassel, Bernard Lejeune, Denis Guilloteau, Sylvie Chalon.
  Journal of Lipid Research. 2002-08-01. 43(8) : 1209-1219.
  10.1194/jlr.M200132-JLR200
• The dopamine mesocorticolimbic pathway is affected by deficiency in n-3 polyunsaturated fatty acids
  Luc Zimmer, Sylvie Vancassel, Sylvain Cantagrel, Patrick Breton, Séraphin Delamanche, Denis Guilloteau, Georges Durand, Sylvie Chalon.
  The American Journal of Clinical Nutrition. 2002-04-01. 75(4) : 662-667.
  10.1093/ajcn/75.4.662
• Neither the density nor function of striatal dopamine transporters were influenced by chronic n-3 polyunsaturated fatty acid deficiency in rodents
  Ercem Kodas, Guylène Page, Luc Zimmer, Sylvie Vancassel, Denis Guilloteau, Georges Durand, Sylvie Chalon.
  Neuroscience Letters. 2002-03-01. 321(1-2) : 95-99.
  10.1016/s0304-3940(01)02481-8
• Polyunsaturated fatty acids and cerebral function: focus on monoaminergic neurotransmission
  Sylvie Chalon, Sylvie Vancassel, Luc Zimmer, Denis Guilloteau, Georges Durand.
  Lipids. 2001-09-01. 36(9) : 937-944.
  10.1007/s11745-001-0804-7
• Analysis of biogenic amines by solid-phase microextraction and high-performance liquid chromatography with electrochemical detection
  J Auger, R Boulay, B Jaillais, S Delion-Vancassel.
  Journal of Chromatography A. 2000-02-01. 870(1-2) : 395-403.
  10.1016/S0021-9673(99)01077-8
• α-Linolenic acid deficiency modifies distractibility but not anxiety and locomotion in rats during aging.
  Catherine Belzung, Anne-Marie Leguisquet, Serge Barreau, Sylvie Delion-Vancassel, Sylvie Chalon, Georges Durand.
  The Journal of Nutrition. 1998-09-01. 128(9) : 1537-1542.
  10.1093/jn/128.9.1537