Quentin Leyrolle

Scientific articles

• Microglial Cannabinoid Type 1 Receptor Regulates Brain Inflammation in a Sex-Specific Manner
  Julia De Meij, Zain Alfanek, Lydie Morel, Fanny Decoeur, Quentin Leyrolle, Katherine Picard, Micael Carrier, Agnes Aubert, Alexandra Séré, Céline Lucas, Gerald Laforest, Jean-Christophe Helbling, Marie-Eve Tremblay, Daniela Cota, Marie-Pierre Moisan, Giovanni Marsicano, Sophie Layé, Agnès Nadjar.
  Cannabis and Cannabinoid Research. 2021-12-01. 6(6) : 488-507.
  10.1089/can.2020.0170
• Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with severe alcohol use disorder
  Sophie Leclercq, Hany Ahmed, Camille Amadieu, Géraldine Petit, Ville Koistinen, Quentin Leyrolle, Marie Poncin, Peter Stärkel, Eloise Kok, Pekka J Karhunen, Philippe de Timary, Sophie Laye, Audrey M Neyrinck, Olli K Kärkkäinen, Kati Hanhineva, Nathalie Delzenne.
  eLife. 2024-11-29. 13
  10.7554/eLife.96937
• Dietary Marine Hydrolysate Improves Memory Performance and Social Behavior through Gut Microbiota Remodeling during Aging
  Camille Mougin, Mathilde Chataigner, Céline Lucas, Quentin Leyrolle, Véronique Pallet, Sophie Layé, Elodie Bouvret, Anne-Laure Dinel, Corinne Joffre.
  Foods. 2023-11-21. 12(23) : 4199.
  10.3390/foods12234199
• The gut-derived metabolites as mediators of the effect of healthy nutrition on the brain.
  Quentin Leyrolle, Lucia Prado-Perez, Sophie Layé.
  Front. Nutr.. 2023-06-09. 10
  10.3389/fnut.2023.1155533
• Microbiota-derived metabolites as drivers of gut-brain communication.
  Hany Ahmed, Quentin Leyrolle, Ville Koistinen, Olli Kärkkäinen, Sophie Layé, Nathalie Delzenne, Kati Hanhineva.
  Gut Microbes. 2022-07-28. 14(1)
  10.1080/19490976.2022.2102878
• Microbiota and Metabolite Profiling as Markers of Mood Disorders: A Cross-Sectional Study in Obese Patients
  Quentin Leyrolle, Renata Cserjesi, Romane Demeure, Audrey M. Neyrinck, Camille Amadieu, Julie Rodriguez, Olli Kärkkäinen, Kati Hanhineva, Nicolas Paquot, Miriam Cnop, Patrice D. Cani, Jean-Paul Thissen, Laure B. Bindels, Olivier Klein, Olivier Luminet, Nathalie M. Delzenne.
  Nutrients. 2021-12-29. 14(1) : 147.
  10.3390/nu14010147
• Restoring an adequate dietary fiber intake by inulin supplementation: a pilot study showing an impact on gut microbiota and sociability in alcohol use disorder patients
  Camille Amadieu, Valentin Coste, Audrey M. Neyrinck, Victoria Thijssen, Quentin Leyrolle, Laure B. Bindels, Hubert Piessevaux, Peter Stärkel, Philippe de Timary, Nathalie M. Delzenne, Sophie Leclercq.
  Gut Microbes. 2021-12-20. 14(1)
  10.1080/19490976.2021.2007042
• N‐3 PUFA deficiency disrupts oligodendrocyte maturation and myelin integrity during brain development
  Quentin Leyrolle, Fanny Decoeur, Cyril Dejean, Galadriel Brière, Stephane Leon, Ioannis Bakoyiannis, Emilie Baroux, Tony‐Lee Sterley, Clémentine Bosch‐Bouju, Lydie Morel, Camille Amadieu, Cynthia Lecours, Marie‐Kim St‐Pierre, Maude Bordeleau, Véronique De Smedt‐Peyrusse, Alexandran Séré, Leslie Schwendimann, Stephane Grégoire, Lionel Bretillon, Niyazi Acar, Corinne Joffre, Guillaume Ferreira, Raluca Uricaru, Patricia Thebault, Pierre Gressens, Marie‐Eve Tremblay, Sophie Layé, Agnes Nadjar.
  Glia. 2021-09-14.
  10.1002/glia.24088
• Prebiotic effect on mood in obese patients is determined by the initial gut microbiota composition: A randomized, controlled trial
  Quentin Leyrolle, Renata Cserjesi, Maria D.G.H. Mulders, Giorgia Zamariola, Sophie Hiel, Marco A. Gianfrancesco, Daphné Portheault, Camille Amadieu, Laure B. Bindels, Sophie Leclercq, Julie Rodriguez, Audrey M. Neyrinck, Patrice D. Cani, Nicolas Lanthier, Pierre Trefois, Jérome Bindelle, Nicolas Paquot, Miriam Cnop, Jean-Paul Thissen, Olivier Klein, Olivier Luminet, Nathalie M. Delzenne.
  Brain, Behavior, and Immunity. 2021-05-01. 94 : 289-298.
  10.1016/j.bbi.2021.01.014
• Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: A cross-sectional study in obese patients
  Quentin Leyrolle, Renata Cserjesi, Maria D.G.H. Mulders, Giorgia Zamariola, Sophie Hiel, Marco A. Gianfrancesco, Julie Rodriguez, Daphnée Portheault, Camille Amadieu, Sophie Leclercq, Laure B. Bindels, Audrey M. Neyrinck, Patrice D. Cani, Olli Karkkainen, Kati Hanhineva, Nicolas Lanthier, Pierre Trefois, Nicolas Paquot, Miriam Cnop, Jean-Paul Thissen, Olivier Klein, Olivier Luminet, Nathalie M. Delzenne.
  Clinical Nutrition. 2021-04-01. 40(4) : 2035-2044.
  10.1016/j.clnu.2020.09.025
• Hepatoprotective Effects of Indole, a Gut Microbial Metabolite, in Leptin-Deficient Obese Mice
  Christelle Knudsen, Audrey M Neyrinck, Quentin Leyrolle, Pamela Baldin, Sophie Leclercq, Julie Rodriguez, Martin Beaumont, Patrice D Cani, Laure B Bindels, Nicolas Lanthier, Nathalie M Delzenne.
  The Journal of Nutrition. 2021-03-10. 151(6) : 1507-1516.
  10.1093/jn/nxab032
• Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain.
  C. Madore, Q. Leyrolle, L. Morel, M. Rossitto, A. D. Greenhalgh, J. C. Delpech, M. Martinat, C. Bosch-Bouju, J. Bourel, B. Rani, C. Lacabanne, A. Thomazeau, K. E. Hopperton, S. Beccari, A. Sere, A. Aubert, V. De Smedt-Peyrusse, C. Lecours, K. Bisht, L. Fourgeaud, S. Gregoire, L. Bretillon, N. Acar, N. J. Grant, J. Badaut, P. Gressens, A. Sierra, O. Butovsky, M. E. Tremblay, R. P. Bazinet, C. Joffre, A. Nadjar, S. Layé.
  Nat Commun. 2020-11-30. 11(1)
  10.1038/s41467-020-19861-z
• Gut Microbiota-Induced Changes in β-Hydroxybutyrate Metabolism Are Linked to Altered Sociability and Depression in Alcohol Use Disorder
  Sophie Leclercq, Tiphaine Le Roy, Sonia Furgiuele, Valentin Coste, Laure B. Bindels, Quentin Leyrolle, Audrey M. Neyrinck, Caroline Quoilin, Camille Amadieu, Géraldine Petit, Laurence Dricot, Vanessa Tagliatti, Patrice D. Cani, Kristin Verbeke, Jean-Marie Colet, Peter Stärkel, Philippe de Timary, Nathalie M. Delzenne.
  Cell Reports. 2020-10-01. 33(2) : 108238.
  10.1016/j.celrep.2020.108238
• Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime
  Q. Leyrolle, F. Decoeur, G. Briere, C. Amadieu, A. R. A. A. Quadros, I. Voytyuk, C. Lacabanne, A. Benmamar-Badel, J. Bourel, A. Aubert, A. Sere, F. Chain, L. Schwendimann, B. Matrot, T. Bourgeois, S. Grégoire, J. G. Leblanc, A. De Moreno De Leblanc, P. Langella, G. R. Fernandes, L. Bretillon, C. Joffre, R. Uricaru, P. Thebault, P. Gressens, J. M. Chatel, S. Layé, A. Nadjar.
  Neuropsychopharmacol.. 2020-08-11.
  10.1038/s41386-020-00793-7
• Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients
  Julie Rodriguez, Sophie Hiel, Audrey M Neyrinck, Tiphaine Le Roy, Sarah A Pötgens, Quentin Leyrolle, Barbara D Pachikian, Marco A Gianfrancesco, Patrice D Cani, Nicolas Paquot, Miriam Cnop, Nicolas Lanthier, Jean-Paul Thissen, Laure B Bindels, Nathalie M Delzenne.
  Gut. 2020-02-10. 69(11) : 1975-1987.
  10.1136/gutjnl-2019-319726
• Food4Gut multicenter randomized placebo-controlled trial. v1
  Sophie Hiel, Marco A. Gianfrancesco, Julie Rodriguez, Daphnée Portheault, Quentin Leyrolle, Laure B. Bindels, Carolina Gomes da Silveira Cauduro, Maria D.G.H. Mulders, Giorgia Zamariola, Anne-Sophie Azzi, Gaetan Kalala, Barbara D. Pachikian, Camille Amadieu, Audrey M. Neyrinck, Audrey Loumaye, Patrice D. Cani, Nicolas Lanthier, Pierre Trefois, Olivier Klein, Olivier Luminet, Jérôme Bindelle, Nicolas Paquot, Miriam Cnop, Jean-Paul Thissen, Nathalie M. Delzenne.
  . 2019-12-16.
  10.17504/protocols.io.baidica6
• SUN-PO285: Implication of the Gut Microbiota in Personalized Metabolic Response to Dietary Inulin in Obese Patients
  J. Rodriguez, A. Neyrinck, T. Le roy, S. Hiel, Q. Leyrolle, L. Bindels, P. Cani, M. Cnop, N. Paquot, N. Lanthier, J.P. Thissen, N. Delzenne.
  Clinical Nutrition. 2019-09-01. 38 : S164.
  10.1016/s0261-5614(19)32915-2