Eric Boué-Grabot

Scientific articles

• Brief early-life motor training induces behavioral changes and alters neuromuscular development in mice
  Camille Quilgars, Eric Boué-Grabot, Philippe de Deurwaerdère, Jean-René Cazalets, Florence E. Perrin, Sandrine S. Bertrand.
  PLoS Biol. 2025-04-21. 23(4) : e3003153.
  10.1371/journal.pbio.3003153
• Purinergic-associated immune responses in neurodegenerative diseases
  Sara Carracedo, Agathe Launay, Paul-Alexandre Dechelle-Marquet, Emilie Faivre, David Blum, Cécile Delarasse, Eric Boué-Grabot.
  Progress in Neurobiology. 2024-12-01. 243 : 102693.
  10.1016/j.pneurobio.2024.102693
• P2X4 signalling contributes to hyperactivity but not pain sensitization comorbidity in a mouse model of attention deficit/hyperactivity disorder
  Sarah Bou Sader Nehme, Sandra Sanchez-Sarasua, Ramy Adel, Marie Tuifua, Awatef Ali, Amina E. Essawy, Sherine Abdel Salam, Walid Hleihel, Eric Boué-Grabot, Marc Landry.
  Front. Pharmacol.. 2024-01-04. 14
  10.3389/fphar.2023.1288994
• Microglial P2X4 receptors are essential for spinal neurons hyperexcitability and tactile allodynia in male and female neuropathic mice
  Damien Gilabert, Alexia Duveau, Sara Carracedo, Nathalie Linck, Adeline Langla, Rieko Muramatsu, Friedrich Koch-Nolte, François Rassendren, Thomas Grutter, Pascal Fossat, Eric Boué-Grabot, Lauriane Ulmann.
  iScience. 2023-11-01. 26(11) : 108110.
  10.1016/j.isci.2023.108110
• Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis
  Maëlle Duperray, Fanny Hardet, Elodie Henriet, Christelle Saint-Marc, Eric Boué-Grabot, Bertrand Daignan-Fornier, Karine Massé, Benoît Pinson.
  Cells. 2023-09-28. 12(19) : 2379.
  10.3390/cells12192379
• A photoswitchable inhibitor of TREK channels controls pain in wild-type intact freely moving animals
  Arnaud Landra-Willm, Ameya Karapurkar, Alexia Duveau, Anne Amandine Chassot, Lucille Esnault, Gerard Callejo, Marion Bied, Stephanie Häfner, Florian Lesage, Brigitte Wdziekonski, Anne Baron, Pascal Fossat, Laurent Marsollier, Xavier Gasull, Eric Boué-Grabot, Michael A. Kienzler, Guillaume Sandoz.
  Nat Commun. 2023-03-01. 14(1)
  10.1038/s41467-023-36806-4
• Increased surface P2X4 receptors by mutant SOD1 proteins contribute to ALS pathogenesis in SOD1-G93A mice
  Eléonore Bertin, Audrey Martinez, Anne Fayoux, Kevin Carvalho, Sara Carracedo, Pierre-Olivier Fernagut, Friedrich Koch-Nolte, David Blum, Sandrine S. Bertrand, Eric Boué-Grabot.
  Cell. Mol. Life Sci.. 2022-07-19. 79(8)
  10.1007/s00018-022-04461-5
• P2X7 Receptors and TMEM16 Channels Are Functionally Coupled with Implications for Macropore Formation and Current Facilitation
  Kate Dunning, Adeline Martz, Francisco Andrés Peralta, Federico Cevoli, Eric Boué-Grabot, Vincent Compan, Fanny Gautherat, Patrick Wolf, Thierry Chataigneau, Thomas Grutter.
  IJMS. 2021-06-18. 22(12) : 6542.
  10.3390/ijms22126542
• The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos
  Karine Massé, Surinder Bhamra, Christian Paroissin, Lilly Maneta-Peyret, Eric Boué-Grabot, Elizabeth A. Jones.
  Preprint bioRxiv. 2021-03-05.
  10.1101/2021.03.04.433320
• Role of Conserved Residues and F322 in the Extracellular Vestibule of the Rat P2X7 Receptor in Its Expression, Function and Dye Uptake Ability
  Marian Rupert, Anirban Bhattacharya, Vendula Tvrdonova Stillerova, Marie Jindrichova, Audrey Mokdad, Eric Boué-Grabot, Hana Zemkova.
  IJMS. 2020-11-10. 21(22) : 8446.
  10.3390/ijms21228446
• Animal models of pain: diversity and benefits
  Cynthia Abboud, Alexia Duveau, Rabia Bouali-Benazzouz, Karine Massé, Joseph Mattar, Louison Brochoire, Pascal Fossat, Eric Boué-Grabot, Walid Hleihel, Marc Landry.
  Journal of Neuroscience Methods. 2020-11-01. : 108997.
  10.1016/j.jneumeth.2020.108997
• Cross-Talk between P2X and NMDA Receptors
  Larry Rodriguez, Catherine Yi, Cameron Chu, Quentin Duriez, Sharyse Watanabe, Megan Ryu, Brandon Reyes, Liana Asatryan, Eric Boué-Grabot, Daryl Davies.
  IJMS. 2020-09-29. 21(19) : 7187.
  10.3390/ijms21197187
• Implication of Neuronal Versus Microglial P2X4 Receptors in Central Nervous System Disorders
  Alexia Duveau, Eléonore Bertin, Eric Boué-Grabot.
  Neurosci. Bull.. 2020-09-05.
  10.1007/s12264-020-00570-y
• Editorial: Purinergic Signaling in Health and Disease
  Eric Boué-Grabot, David Blum, Stefania Ceruti.
  Front. Cell. Neurosci.. 2020-02-04. 14
  10.3389/fncel.2020.00015
• Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice
  Eléonore Bertin, Thomas Deluc, Kjara S. Pilch, Audrey Martinez, Johan-Till Pougnet, Evelyne Doudnikoff, Anne-Emilie Allain, Philine Bergmann, Marion Russeau, Estelle Toulmé, Erwan Bezard, Friedrich Koch-Nolte, Philippe Séguéla, Sabine Lévi, Bruno Bontempi, François Georges, Sandrine S. Bertrand, Olivier Nicole, Eric Boué-Grabot.
  Mol Psychiatry. 2020-01-08.
  10.1038/s41380-019-0641-8
• Purinergic Signaling in Health and Disease
  Eric Boué-Grabot.
  Frontiers Research Topics. 2020-01-01.
  10.3389/978-2-88963-556-6
• P2X Electrophysiology and Surface Trafficking in Xenopus Oocytes
  Eléonore Bertin, Audrey Martínez, Eric Boué-Grabot.
  Methods in Molecular Biology. 2019-10-24. : 243-259.
  10.1007/978-1-4939-9717-6_18
• Comparative Embryonic Spatio-Temporal Expression Profile Map of the Xenopus P2X Receptor Family
  Camille Blanchard, Eric Boué-Grabot, Karine Massé.
  Front. Cell. Neurosci.. 2019-07-26. 13
  10.3389/fncel.2019.00340
• Aquaporin-4 Surface Trafficking Regulates Astrocytic Process Motility and Synaptic Activity in Health and Autoimmune Disease.
  Silvia Ciappelloni, Delphine Bouchet, Nadège Dubourdieu, Eric Boué-Grabot, Blanka Kellermayer, Constance Manso, Romain Marignier, Stéphane H.R. Oliet, Thomas Tourdias, Laurent Groc.
  Cell Reports. 2019-06-01. 27(13) : 3860-3872.e4.
  10.1016/j.celrep.2019.05.097
• GAT-3 Dysfunction Generates Tonic Inhibition in External Globus Pallidus Neurons in Parkinsonian Rodents
  Marine Chazalon, Elena Paredes-Rodriguez, Stéphanie Morin, Audrey Martinez, Sofia Cristóvão-Ferreira, Sandra Vaz, Ana Sebastiao, Aude Panatier, Eric Boué-Grabot, Cristina Miguelez, Jérôme Baufreton.
  Cell Reports. 2018-05-01. 23(6) : 1678-1690.
  10.1016/j.celrep.2018.04.014
• Modulation of Central Synapses by Astrocyte-Released ATP and Postsynaptic P2X Receptors
  Eric Boué-Grabot, Yuriy Pankratov.
  Neural Plasticity. 2017-01-01. 2017 : 1-11.
  10.1155/2017/9454275
• Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation.
  W. Danquah, C. Meyer-Schwesinger, B. Rissiek, C. Pinto, A. Serracant-Prat, M. Amadi, D. Iacenda, J.-H. Knop, A. Hammel, P. Bergmann, N. Schwarz, J. Assuncao, W. Rotthier, F. Haag, E. Tolosa, P. Bannas, E. Boue-Grabot, T. Magnus, T. Laeremans, C. Stortelers, F. Koch-Nolte.
  Science Translational Medicine. 2016-11-23. 8(366) : 366ra162-366ra162.
  10.1126/scitranslmed.aaf8463
• Molecular and electrophysiological evidence for a GABAc receptor in thyrotropin-secreting cells.
  Boue-Grabot E, Taupignon A, Tramu G, Garret M..
  Endocrinology.. 2000-05-01. 141(5) : 1627-32.
  10.1210/en.141.5.1627
• An mRNA encoding a putative GABA-gated chloride channel is expressed in the human cardiac conduction system.
  Garret M, Bascles L, Boue-Grabot E, Sartor P, Charron G, Bloch B, Margolskee RF..
  J Neurochem. 1997-04-02. 68(4) : 1382-9.
  
• Intracellular cross talk and physical interaction between two classes of neurotransmitter-gated channels.
  .
  J Neurosci.. 2003-02-15. 23(4) : 1246-53.
  
• P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons.
  Johan-Till Pougnet, Benjamin Compans, Audrey Martinez, Daniel Choquet, Eric Hosy, Eric Boué-Grabot.
  Sci Rep. 2016-09-14. 6(1)
  10.1038/srep31836
• Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA-Induced Dyskinesia.
  Michel Engeln, Matthieu F. Bastide, Estelle Toulmé, Benjamin Dehay, Mathieu Bourdenx, Evelyne Doudnikoff, Qin Li, Christian E. Gross, Eric Boué-Grabot, Antonio Pisani, Erwan Bezard, Pierre-Olivier Fernagut.
  Biological Psychiatry. 2016-03-01. 79(5) : 354-361.
  10.1016/j.biopsych.2014.07.007
• A New Mechanism of Receptor Targeting by Interaction between Two Classes of Ligand-Gated Ion Channels
  Michel Boris Emerit, Camille Baranowski, Jorge Diaz, Audrey Martinez, Julie Areias, Jeanine Alterio, Justine Masson, Eric Boué-Grabot, Michèle Darmon.
  J. Neurosci.. 2016-02-03. 36(5) : 1456-1470.
  10.1523/JNEUROSCI.2390-15.2016
• ATP P2X receptors downregulate AMPA receptor trafficking and postsynaptic efficacy in hippocampal neurons.
  Johan-Till Pougnet, Estelle Toulme, Audrey Martinez, Daniel Choquet, Eric Hosy, Eric Boué-Grabot.
  Neuron. 2014-07-01. 83(2) : 417-430.
  10.1016/j.neuron.2014.06.005
• Long distance effect on ligand-gated ion channels extracellular domain may affect interactions with the intracellular machinery.
  Maurice Garret, Eric Boué-Grabot, Antoine Taly.
  Communicative & Integrative Biology. 2014-01-30. 7(1) : e27984.
  10.4161/cib.27984
• Inhibition of P2X4 function by P2Y6 UDP receptors in microglia.
  Louis-Philippe Bernier, Ariel R. Ase, Éric Boué-Grabot, Philippe Séguéla.
  Glia. 2013-10-07. 61(12) : 2038-2049.
  10.1002/glia.22574
• Agonist-dependent endocytosis of γ-aminobutyric acid type A (GABAA) receptors revealed by a γ2(R43Q) epilepsy mutation.
  Severine Chaumont, Caroline André, David Perrais, Eric Boué-Grabot, Antoine Taly, Maurice Garret.
  J. Biol. Chem.. 2013-08-09. 288(39) : 28254-28265.
  10.1074/jbc.M113.470807
• A dual polybasic motif determines phosphoinositide binding and regulation in the P2X channel family.
  Louis-Philippe Bernier, Dominique Blais, Éric Boué-Grabot, Philippe Séguéla.
  PLoS ONE. 2012-07-11. 7(7) : e40595.
  10.1371/journal.pone.0040595
• P2X4 receptor channels form large noncytolytic pores in resting and activated microglia.
  Louis-Philippe Bernier, Ariel R. Ase, Éric Boué-Grabot, Philippe Séguéla.
  Glia. 2012-02-08. 60(5) : 728-737.
  10.1002/glia.22301
• Interplay between ionotropic receptors modulates inhibitory synaptic strength.
  Young-Hwan Jo, Eric Boué-Grabot.
  Communicative & Integrative Biology. 2011-11-01. 4(6) : 706-709.
  10.4161/cib.17291
• Interplay between ionotropic receptors modulates inhibitory synaptic strength.
  Young-Hwan Jo, Eric Boué-Grabot.
  Communicative & Integrative Biology. 2011-11-01. 4(6) : 706-709.
  10.4161/cib.17291
• Cross-talk between P2X4 and gamma-aminobutyric acid, type A receptors determines synaptic efficacy at a central synapse.
  Young-Hwan Jo, Emmanuelle Donier, Audrey Martinez, Maurice Garret, Estelle Toulmé, Eric Boué-Grabot.
  J. Biol. Chem.. 2011-04-11. 286(22) : 19993-20004.
  10.1074/jbc.m111.231324
• Selective potentiation of homomeric P2X2 ionotropic ATP receptors by a fast non-genomic action of progesterone.
  Mathias De Roo, Eric Boué-Grabot, Rémy Schlichter.
  Neuropharmacology. 2010-03-01. 58(3) : 569-577.
  10.1016/j.neuropharm.2009.12.002
• Inhibitory transmission in locus coeruleus neurons expressing GABA a receptor epsilon subunit has a number of unique properties
  P. Belujon, J. Baufreton, L. Grandoso, E. Boué-Grabot, T.F.C. Batten, L. Ugedo, M. Garret, A. I. Taupignon.
  Journal of Neurophysiology. 2009-10-01. 102(4) : 2312-2325.
  10.1152/jn.00227.2009
• Phosphoinositides regulate P2X4 ATP-gated channels through direct interactions.
  L.-P. Bernier, A. R. Ase, S. Chevallier, D. Blais, Q. Zhao, E. Boue-Grabot, D. Logothetis, P. Seguela.
  Journal of Neuroscience. 2008-11-26. 28(48) : 12938-12945.
  10.1523/jneurosci.3038-08.2008
• An intracellular motif of P2X(3) receptors is required for functional cross-talk with GABA(A) receptors in nociceptive DRG neurons.
  Estelle Toulmé, Dominique Blais, Claire Léger, Marc Landry, Maurice Garret, Philippe Séguéla, Eric Boué-Grabot.
  J Neurochem. 2007-08-01. 102(4) : 1357-1368.
  10.1111/j.1471-4159.2007.04640.x
• A gamma 2(R43Q) mutation, linked to epilepsy in humans, alters GABAA receptor assembly and modifies subunit composition on the cell surface.
  G. Frugier, F. Coussen, M.-F. Giraud, M.-F. Odessa, M. B. Emerit, E. Boue-Grabot, M. Garret.
  Journal of Biological Chemistry. 2006-11-30. 282(6) : 3819-3828.
  10.1074/jbc.m608910200
• Functional properties of internalization-deficient P2X4 receptors reveal a novel mechanism of ligand-gated channel facilitation by ivermectin.
  E. Toulme.
  Molecular Pharmacology. 2005-11-17. 69(2) : 576-587.
  10.1124/mol.105.018812
• Subunit-specific coupling between gamma-aminobutyric acid type A and P2X2 receptor channels.
  Éric Boué-Grabot, Estelle Toulmé, Michel B. Émerit, Maurice Garret.
  J. Biol. Chem.. 2004-09-29. 279(50) : 52517-52525.
  10.1074/jbc.m410223200
• Selective knock-down of P2X7 ATP receptor function by dominant-negative subunits.
  R. Raouf.
  Molecular Pharmacology. 2004-03-01. 65(3) : 646-654.
  10.1124/mol.65.3.646
• Cross-talk and co-trafficking between rho1/GABA receptors and ATP-gated channels.
  Éric Boué-Grabot, Michel B. Émerit, Estelle Toulmé, Philippe Séguéla, Maurice Garret.
  J. Biol. Chem.. 2003-12-01. 279(8) : 6967-6975.
  10.1074/jbc.m307772200
• Intracellular Cross Talk and Physical Interaction between Two Classes of Neurotransmitter-Gated Channels
  Éric Boué-Grabot, Carlos Barajas-López, Yassar Chakfe, Dominique Blais, Danny Bélanger, Michel B. Émerit, Philippe Séguéla.
  J. Neurosci.. 2003-02-15. 23(4) : 1246-1253.
  10.1523/JNEUROSCI.23-04-01246.2003
• An mRNA Encoding a Putative GABA-Gated Chloride Channel Is Expressed in the Human Cardiac Conduction System
  Maurice Garret, Lionel Bascles, Eric Boue-Grabot, Pierre Sartor, Gisele Charron, Bertrand Bloch, Robert F. Margolskee.
  Journal of Neurochemistry. 2002-11-18. 68(4) : 1382-1389.
  10.1046/j.1471-4159.1997.68041382.x
• Unique functional properties of a sensory neuronal P2X ATP-gated channel from zebrafish.
  Éric Boué-Grabot, Marie-Andrée Akimenko, Philippe Séguéla.
  Journal of Neurochemistry. 2002-01-04. 75(4) : 1600-1607.
  10.1046/j.1471-4159.2000.0751600.x
• Molecular and electrophysiological evidence for a GABAC receptor in thyrotropin-secreting cells
  E. Boue-Grabot.
  Endocrinology. 2000-05-01. 141(5) : 1627-1632.
  10.1210/en.141.5.1627
• A protein kinase C site highly conserved in P2X subunits controls the desensitization kinetics of P2X(2) ATP-gated channels.
  Éric Boué-Grabot, Vincent Archambault, Philippe Séguéla.
  J. Biol. Chem.. 2000-03-31. 275(14) : 10190-10195.
  10.1074/jbc.275.14.10190
• Functional and biochemical evidence for heteromeric ATP-gated channels composed of P2X1 and P2X5 subunits.
  Khanh-Tuoc Lê, Éric Boué-Grabot, Vincent Archambault, Philippe Séguéla.
  J. Biol. Chem.. 1999-05-28. 274(22) : 15415-15419.
  10.1074/jbc.274.22.15415
• Expression of GABA receptor ρ subunits in rat brain
  Eric Boue‐Grabot, Morad Roudbaraki, Lionel Bascles, Gerard Tramu, Bertrand Bloch, Maurice Garret.
  Journal of Neurochemistry. 1998-03-01. 70(3) : 899-907.
  10.1046/j.1471-4159.1998.70030899.x
• Regulation of Intracellular pH in Rat Lactotrophs: Involvement of Anionic Exchangers*
  L. Garcia, E. Boué-Grabot, M. Garret, P. Sartor.
  Endocrinology. 1997-10-01. 138(10) : 4191-4198.
  10.1210/endo.138.10.5460
• Regulation of intracellular pH in rat lactotrophs: involvement of anionic exchangers.
  L. Garcia.
  Endocrinology. 1997-10-01. 138(10) : 4191-4198.
  10.1210/en.138.10.4191
• Processed pseudogenes interfere with reverse transcriptase-polymerase chain reaction controls.
  Bertrand Garbay, Eric Boue-Grabot, Maurice Garret.
  Analytical Biochemistry. 1996-05-01. 237(1) : 157-159.
  10.1006/abio.1996.0218
• Molecular diversity of GABA-gated chloride channels in the rat anterior pituitary.
  Eric Boué-Grabot, Bernard Dufy, Maurice Garret.
  Brain Research. 1995-12-01. 704(1) : 125-129.
  10.1016/0006-8993(95)01192-7