Severine Deforges

Scientific articles

• A novel AAV9-dual microRNA-vector targeting GRIK2 in the hippocampus as a treatment for mesial temporal lobe epilepsy.
  Stéphane J. Baudouin, April R. Giles, Nick Pearson, Severine Deforges, Chenxia He, Céline Boileau, Nicolas Partouche, Andreas Borta, Justine Gautron, Morgane Wartel, Irena Bočkaj, Didier Scavarda, Fabrice Bartolomei, Guillaume Penchet, Jérôme Aupy, Jennifer Sims, Jared Smith, Andrew Mercer, Olivier Danos, Christophe Mulle, Valérie Crépel, Richard Porter.
  Molecular Therapy - Methods & Clinical Development. 2024-12-01. 32(4) : 101342.
  10.1016/j.omtm.2024.101342
• GluK2 Is a Target for Gene Therapy in Drug‐Resistant Temporal Lobe Epilepsy
  Céline Boileau, Severine Deforges, Angélique Peret, Didier Scavarda, Fabrice Bartolomei, April Giles, Nicolas Partouche, Justine Gautron, Julio Viotti, Haley Janowitz, Guillaume Penchet, Cécile Marchal, Stanislas Lagarde, Agnès Trebuchon, Nathalie Villeneuve, Julie Rumi, Thomas Marissal, Roustem Khazipov, Ilgam Khalilov, Fanny Martineau, Marine Maréchal, Anne Lepine, Mathieu Milh, Dominique Figarella‐Branger, Etienne Dougy, Soutsakhone Tong, Romain Appay, Stéphane Baudouin, Andrew Mercer, Jared B. Smith, Olivier Danos, Richard Porter, Christophe Mulle, Valérie Crépel.
  Annals of Neurology. 2023-07-06. 94(4) : 745-761.
  10.1002/ana.26723
• Presenilin and APP regulate synaptic kainate receptors.
  Gael Barthet, Ana Moreira- de-Sá, Pei Zhang, Séverine Deforges, Jorge Castanheira, Adam Gorlewicz, Christophe Mulle.
  J. Neurosci.. 2022-10-26. : JN-RM-0297-22.
  10.1523/jneurosci.0297-22.2022
• Astroglial ER-mitochondria calcium transfer mediates endocannabinoid-dependent synaptic integration
  Roman Serrat, Ana Covelo, Vladimir Kouskoff, Sebastien Delcasso, Andrea Ruiz-Calvo, Nicolas Chenouard, Carol Stella, Corinne Blancard, Benedicte Salin, Francisca Julio-Kalajzić, Astrid Cannich, Federico Massa, Marjorie Varilh, Severine Deforges, Laurie M. Robin, Diego De Stefani, Arnau Busquets-Garcia, Frederic Gambino, Anna Beyeler, Sandrine Pouvreau, Giovanni Marsicano.
  Cell Reports. 2021-12-01. 37(12) : 110133.
  10.1016/j.celrep.2021.110133
• Impaired plasticity of intrinsic excitability in the dentate gyrus alters spike transfer in a mouse model of Alzheimer’s disease
  Nan Jiang, Dario Cupolillo, Noelle Grosjean, Emeline Muller, Séverine Deforges, Christophe Mulle, Thierry Amédée.
  Neurobiology of Disease. 2021-03.
  10.1016/j.nbd.2021.105345
• PGE2-EP3 signaling pathway impairs hippocampal presynaptic long-term plasticity in a mouse model of Alzheimer’s disease.
  Vincent Maingret, Gaël Barthet, Séverine Deforges, Nan Jiang, Christophe Mulle, Thierry Amédée.
  Neurobiology of Aging. 2017-02-01. 50 : 13-24.
  10.1016/j.neurobiolaging.2016.10.012