Muriel Darnaudéry
University Teacher - Researcher
Professor Researcher (PU) / Université de Bordeaux/ Contact
+33 5 57 57 12 32
www.orcid.org/0000-0003-0209-3880
/ Address of work
NutriNeuro - Bâtiment UFR Pharmacie - 2e tranche – 2e étage - Case 34 - 146 rue Léo-Saignat - 33076 Bordeaux Cedex
I am working on the hypothesis of the developmental origin of adult health and diseases using an integrative approach. My research is dedicated to the exploration of the role of early-life environment (nutrition, maternal obesity, maternal diabetes, maternal stress) on brain functions and vulnerability to neuropsychiatric diseases (depression, anxiety) in offspring using preclinical models. Our work indicates that adverse early-life events (both during pre- and postnatal periods) increase the allostatic load and program the brain vulnerability to stress later in life. I also explore the causal role of gut-brain dysfunctions (gut microbiota dysbiosis and gut leakiness) in the emergence of deficits associated with early-life stress.
Scientific articles
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Strain-specific changes in nucleus accumbens transcriptome and motivation for palatable food reward in mice exposed to maternal separation.
Simon Benoit, Mathilde Henry, Sara Fneich, Alexia Mathou, Lin Xia, Aline Foury, Mélanie Jouin, Claudine Junien, Lucile Capuron, Luc Jouneau, Marie-Pierre Moisan, Cyrille Delpierre, Anne Gabory, Muriel Darnaudéry.
Front. Nutr.. 2023-07-26. 10
10.3389/fnut.2023.1190392 -
A Holistic View of the Goto-Kakizaki Rat Immune System: Decreased Circulating Immune Markers in Non- Obese Type 2 Diabetes
Snehaa V. Seal, Mathilde Henry, Clémentine Pajot, Cyrielle Holuka, Danielle Bailbé, Jamileh Movassat, Muriel Darnaudéry, Jonathan D. Turner.
Front. Immunol.. 2022-05-23. 13
10.3389/fimmu.2022.896179 -
A new experimental design to study inflammation-related versus non-inflammation-related depression in mice
Pierre Cardinal, Camille Monchaux de Oliveira, Julie Sauvant, Aline Foury, Muriel Darnaudéry, Sylvie Vancassel, Nathalie Castanon, Lucile Capuron.
J Neuroinflammation. 2021-12-01. 18(1)
10.1186/s12974-021-02330-9 -
Targeted intestinal tight junction hyperpermeability alters the microbiome, behavior, and visceromotor responses
Orsolya Inczefi, Valérie Bacquié, Maïwenn Olier-Pierre, Marion Rincel, Belinda Ringot-Destrez, Sandrine Ellero-Simatos, Hélène Eutamène, Colette Bétoulières, Julie Thomas, Justin Laine, Louise Gros, Mathilde Lévêque, Renaud Leonard, Cherryl Harkat, Catherine Robbe-Masselot, Richard Roka, Muriel Mercier-Bonin, Vassilia Theodorou, Muriel Darnaudéry, Jerrold R. Turner, Laurent Ferrier.
Cellular and Molecular Gastroenterology and Hepatology. 2020-03-01.
10.1016/j.jcmgh.2020.02.008 -
Maternal separation in rodents: a journey from gut to brain and nutritional perspectives
Marion Rincel, Muriel Darnaudéry.
Proceedings of the Nutrition Society. 2019-06-28.
10.1017/s0029665119000958 -
Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner
Rincel M, Aubert P, Chevalier J, Grohard PA, Basso L, Monchaux de Oliveira C, Helbling JC, Lévy É, Chevalier G, Leboyer M, Eberl G, Layé S, Capuron L, Vergnolle N, Neunlist M, Boudin H, Lepage P, Darnaudéry M..
Brain Behav Immun.. 2019-03-11.
10.1016/j.bbi.2019.03.006 -
Pharmacological restoration of gut barrier function in stressed neonates partially reverses long-term alterations associated with maternal separation
Marion Rincel, Maïwenn Olier, Amandine Minni, Camille Monchaux de Oliveira, Yann Matime, Eric Gaultier, Isabelle Grit, Jean-Christophe Helbling, Anna Maria Costa, Amandine Lépinay, Marie-Pierre Moisan, Sophie Layé, Laurent Ferrier, Patricia Parnet, Vassilia Theodorou, Muriel Darnaudéry.
Psychopharmacology. 2019-05-01. 236(5) : 1583-1596.
10.1007/s00213-019-05252-w -
Prenatal retinoic acid exposure reveals candidate genes for craniofacial disorders
Berenguer Marie, Darnaudery Muriel, Claverol Stéphane, Bonneu Marc, Lacombe Didier & Rooryck Caroline..
Scientific Reports. 2018-11.
10.1038/s41598-018-35681-0. -
Unlimited sucrose consumption during adolescence generates a depressive-like phenotype in adulthood
Aliou B. Gueye, Leandro F. Vendruscolo, Camila de Ávila, Catherine Le Moine, Muriel Darnaudéry, Martine Cador.
Neuropsychopharmacol. 2018-12-27. 43(13) : 2627-2635.
10.1038/s41386-018-0025-9 -
Maternal high-fat diet and early life stress differentially modulate spine density and dendritic morphology in the medial prefrontal cortex of juvenile and adult rats.
Marion Rincel, Amandine L. Lépinay, Yoottana Janthakhin, Gwenaëlle Soudain, Sophie Yvon, Stéphanie Da Silva, Corinne Joffre, Agnès Aubert, Alexandra Séré, Sophie Layé, Vassilia Theodorou, Guillaume Ferreira, Muriel Darnaudéry.
Brain Struct Funct. 2017-10-11. 223(2) : 883-895.
10.1007/s00429-017-1526-8 -
Gender specific behavioral alterations are associated with gut dysbiosis in mice exposed to multifactorial early-life adversity
M. Rincel, P. Aubert, J. Chevalier, P. Grohard, L. Basso, C. Monchaux, De Oliveira, E. Lévy, G. Chevalier, M. Leboyer, G. Eberl, N. Vergnolle, M. Neunlist, S. Layé, L. Capuron, H. Boudin, P. Lepage, M. Darnaudéry.
European Neuropsychopharmacology. 2017-10-01. 27 : S682-S683.
10.1016/s0924-977x(17)31269-5 -
Early restoration of gut barrier function abrogates the long-term neurobehavioral effects of early-life stress in rats
Marion Rincel, Amandine Minni, Maïwenn Olier, Camille Monchaux de Oliveira, Yann Matime, Julie Thomas, Eric Gauthier, Isabelle Grit, Anna-Maria Costa, Amandine Lépinay, Sophie Layé, Laurent Ferrier, Patricia Parnet, Vassilia Théodorou, Muriel Darnaudéry.
Psychoneuroendocrinology. 2017-09-01. 83 : 79.
10.1016/j.psyneuen.2017.07.450 -
Maternal high-fat diet leads to hippocampal and amygdala dendritic remodeling in adult male offspring.
Yoottana Janthakhin, Marion Rincel, Anna-Maria Costa, Muriel Darnaudéry, Guillaume Ferreira.
Psychoneuroendocrinology. 2017-09-01. 83 : 49-57.
10.1016/j.psyneuen.2017.05.003 -
Impact of perinatal exposure to high-fat diet and stress on responses to nutritional challenges, food-motivated behaviour and mesolimbic dopamine function.
M Romaní-Pérez, A L Lépinay, L Alonso, M Rincel, L Xia, H Fanet, S Caillé, M Cador, S Layé, S Vancassel, M Darnaudéry.
Int J Obes. 2016-12-27. 41(4) : 502-509.
10.1038/ijo.2016.236 -
Maternal high-fat diet prevents developmental programming by early-life stress
M Rincel, A L Lépinay, P Delage, J Fioramonti, V S Théodorou, S Layé, M Darnaudéry.
Transl Psychiatry. 2016-11-01. 6(11) : e966-e966.
10.1038/tp.2016.235 -
The early life nutritional environment and early life stress as potential pathways towards the metabolic syndrome in mid-life? A lifecourse analysis using the 1958 British Birth cohort
C. Delpierre, R. Fantin, C. Barboza-Solis, B. Lepage, M. Darnaudéry, M. Kelly-Irving.
BMC Public Health. 2016-08-18. 16(1)
10.1186/s12889-016-3484-0 -
Les adversités durant l’enfance et la charge allostatique à l’âge adulte : résultats de la cohorte de naissances britannique de 1958
C. Barboza-Solis, M. Kelly-Irving, R. Fantin, M. Darnaudéry, J. Torrisani, T. Lang, C. Delpierre.
Revue d'Épidémiologie et de Santé Publique. 2016-04-01. 64 : S99.
10.1016/j.respe.2015.07.008 -
Origins of heath inequalities: the case for Allostatic Load
Cyrille Delpierre, Cristina Barbosa-Solis, Jerome Torrisani, Muriel Darnaudery, Melanie Bartley, David Blane, Michelle Kelly-Irving, Linn Getz, Margret Olafia Tomasdottir, Tony Roberston, Per E. Gustafsson.
LLCS. 2016-01-28. 7(1)
10.14301/llcs.v7i1.325 -
Early life stressful experiences and neuropsychiatric vulnerability: evidences from human and animal models
Marion Rincel, Amandine Lépinay, Anne Gabory, Vassilia Théodorou, Muriel Koehl, Valérie Daugé, Stefania Maccari, Muriel Darnaudéry.
Med Sci (Paris). 2016-01-01. 32(1) : 93-99.
10.1051/medsci/20163201015 -
Environnement précoce et vulnérabilité neuropsychiatrique
Marion Rincel, Amandine Lépinay, Anne Gabory, Vassilia Théodorou, Muriel Koehl, Valérie Daugé, Stefania Maccari, Muriel Darnaudéry.
Med Sci (Paris). 2016-01-01. 32(1) : 93-99.
10.1051/medsci/20163201015 -
Tu1877 Targeted Epithelial Barrier Disruption Reveals IBS-Like Pathophysiology and Behavioral Modifications
Laurent Ferrier, Orsolya Inczefi, Amandine Lépinay, lin xia, Mathilde Leveque, Sophie Layé, Jerrold R. Turner, Muriel D. darnaudery, Vassilia Theodorou.
Gastroenterology. 2015-04-01. 148(4) : S-925.
10.1016/s0016-5085(15)33147-4 -
Juvenile obesity enhances emotional memory and amygdala plasticity through glucocorticoids.
C. Boitard, M. Maroun, F. Tantot, A. Cavaroc, J. Sauvant, A. Marchand, S. Laye, L. Capuron, M. Darnaudery, N. Castanon, E. Coutureau, R.-M. Vouimba, G. Ferreira.
Journal of Neuroscience. 2015-03-04. 35(9) : 4092-4103.
10.1523/jneurosci.3122-14.2015 -
Perinatal high-fat diet increases hippocampal vulnerability to the adverse effects of subsequent high-fat feeding.
Amandine L. Lépinay, Thomas Larrieu, Corinne Joffre, Niyazi Acar, Iciar Gárate, Nathalie Castanon, Guillaume Ferreira, Bénédicte Langelier, Philippe Guesnet, Lionel Brétillon, Patricia Parnet, Sophie Layé, Muriel Darnaudéry.
Psychoneuroendocrinology. 2015-03-01. 53 : 82-93.
10.1016/j.psyneuen.2014.12.008 -
Adverse childhood experiences and physiological wear-and-tear in midlife: Findings from the 1958 British birth cohort
Cristina Barboza Solís, Michelle Kelly-Irving, Romain Fantin, Muriel Darnaudéry, Jérôme Torrisani, Thierry Lang, Cyrille Delpierre.
Proc Natl Acad Sci USA. 2015-02-02. 112(7) : E738-E746.
10.1073/pnas.1417325112 -
Anxiety-like behaviour and associated neurochemical and endocrinological alterations in male pups exposed to prenatal stress
Charlotte Laloux, Jérôme Mairesse, Gilles Van Camp, Angela Giovine, Igor Branchi, Sebastien Bouret, Sara Morley-Fletcher, Gabriela Bergonzelli, Marithé Malagodi, Roberto Gradini, Ferdinando Nicoletti, Muriel Darnaudéry, Stefania Maccari.
Psychoneuroendocrinology. 2012-10-01. 37(10) : 1646-1658.
10.1016/j.psyneuen.2012.02.010 -
Impact of early life stress on alcohol consumption and on the short- and long-term responses to alcohol in adolescent female rats
V. Van Waes, M. Darnaudéry, J. Marrocco, S.H. Gruber, E. Talavera, J. Mairesse, G. Van Camp, B. Casolla, F. Nicoletti, A.A. Mathé, S. Maccari, S. Morley-Fletcher.
Behavioural Brain Research. 2011-08-01. 221(1) : 43-49.
10.1016/j.bbr.2011.02.033 -
ROCK inhibition prevents tau hyperphosphorylation and p25/CDK5 increase after global cerebral ischemia.
John Fredy Castro-Alvarez, Johanna Gutierrez-Vargas, Muriel Darnaudéry, Gloria Patricia Cardona-Gómez.
Behavioral Neuroscience. 2011-01-01. 125(3) : 465-472.
10.1037/a0023167 -
Reduced alcohol drinking in adult rats exposed to sucrose during adolescence
Leandro F. Vendruscolo, Aliou Badara Gueye, Janaína C.M. Vendruscolo, Kelly J. Clemens, Pierre Mormède, Muriel Darnaudéry, Martine Cador.
Neuropharmacology. 2010-11-01. 59(6) : 388-394.
10.1016/j.neuropharm.2010.05.015 -
Sugar overconsumption during adolescence selectively alters motivation and reward function in adult rats.
Leandro F. Vendruscolo, Aliou B. Gueye, Muriel Darnaudéry, Serge H. Ahmed, Martine Cador.
PLoS ONE. 2010-02-19. 5(2) : e9296.
10.1371/journal.pone.0009296 -
Effect of prenatal stress on alcohol preference and sensitivity to chronic alcohol exposure in male rats
Vincent Van Waes, Mihaela Enache, Olivier Berton, Elisabeth Vinner, Michel Lhermitte, Stefania Maccari, Muriel Darnaudéry.
Psychopharmacology. 2010-01-27. 214(1) : 197-208.
10.1007/s00213-009-1765-3 -
Ethanol Attenuates Spatial Memory Deficits and Increases mGlu1a Receptor Expression in the Hippocampus of Rats Exposed to Prenatal Stress
Vincent Van Waes, Mihaela Enache, Annarita Zuena, Jérôme Mairesse, Ferdinando Nicoletti, Elisabeth Vinner, Michel Lhermitte, Stefania Maccari, Muriel Darnaudéry.
Alcoholism: Clinical and Experimental Research. 2009-08-01. 33(8) : 1346-1354.
10.1111/j.1530-0277.2009.00964.x -
Impaired interleukin-1beta and c-Fos expression in the hippocampus is associated with a spatial memory deficit in P2X(7) receptor-deficient mice.
Virginie F. Labrousse, Laurence Costes, Agnès Aubert, Muriel Darnaudéry, Guillaume Ferreira, Thierry Amédée, Sophie Layé.
PLoS ONE. 2009-06-23. 4(6) : e6006.
10.1371/journal.pone.0006006 -
Prenatal stress exacerbates the impact of an aversive procedure on the corticosterone response to stress in female rats
Hélène Louvart, Stefania Maccari, Guillaume Vaiva, Muriel Darnaudéry.
Psychoneuroendocrinology. 2009-06-01. 34(5) : 786-790.
10.1016/j.psyneuen.2008.12.002 -
Epigenetic programming of the stress response in male and female rats by prenatal restraint stress
Muriel Darnaudéry, Stefania Maccari.
Brain Research Reviews. 2008-03-01. 57(2) : 571-585.
10.1016/j.brainresrev.2007.11.004 -
Impact of an acute exposure to ethanol on the oxidative stress status in the hippocampus of prenatal restraint stress adolescent male rats
Mihaela Enache, Vincent Van Waes, Elisabeth Vinner, Michel Lhermitte, Stefania Maccari, Muriel Darnaudéry.
Brain Research. 2008-01-01. 1191 : 55-62.
10.1016/j.brainres.2007.11.031 -
Early motherhood in rats is associated with a modification of hippocampal function
Muriel Darnaudéry, Margarita Perez-Martin, Fabien Del Favero, Carmen Gomez-Roldan, Luis Miguel Garcia-Segura, Stefania Maccari.
Psychoneuroendocrinology. 2007-08-01. 32(7) : 803-812.
10.1016/j.psyneuen.2007.05.012 -
Estradiol, insulin-like growth factor-I and brain aging
Luis M. Garcia-Segura, Yolanda Diz-Chaves, Margarita Perez-Martin, Muriel Darnaudéry.
Psychoneuroendocrinology. 2007-08-01. 32 : S57-S61.
10.1016/j.psyneuen.2007.03.001 -
Maternal stress alters endocrine function of the feto-placental unit in rats
Jérôme Mairesse, Jean Lesage, Christophe Breton, Bernadette Bréant, Tom Hahn, Muriel Darnaudéry, Suzanne L. Dickson, Jonathan Seckl, Bertrand Blondeau, Didier Vieau, Stefania Maccari, Odile Viltart.
American Journal of Physiology-Endocrinology and Metabolism. 2007-06-01. 292(6) : E1526-E1533.
10.1152/ajpendo.00574.2006 -
Impact of an intense stress on ethanol consumption in female rats characterized by their pre-stress preference: Modulation by prenatal stress
M. Darnaudéry, H. Louvart, L. Defrance, M. Léonhardt, S. Morley-Fletcher, S.H. Gruber, G. Galietta, A.A. Mathé, S. Maccari.
Brain Research. 2007-02-01. 1131 : 181-186.
10.1016/j.brainres.2006.11.005 -
Effect of hindlimb unloading on motor activity in adult rats: Impact of prenatal stress.
M. H. Canu, M. Darnaudéry, M. Falempin, S. Maccari, O. Viltart.
Behavioral Neuroscience. 2007-01-01. 121(1) : 177-185.
10.1037/0735-7044.121.1.177 -
Hypo-response of the hypothalamic-pituitary-adrenocortical axis after an ethanol challenge in prenatally stressed adolescent male rats
Vincent Van Waes, Mihaela Enache, Isabelle Dutriez, Jean Lesage, Sara Morley-Fletcher, Elisabeth Vinner, Michel Lhermitte, Didier Vieau, Stefania Maccari, Muriel Darnaudéry.
European Journal of Neuroscience. 2006-08-01. 24(4) : 1193-1200.
10.1111/j.1460-9568.2006.04973.x -
Prenatal stress alters Fos protein expression in hippocampus and locus coeruleus stress-related brain structures
Odile Viltart, Jérôme Mairesse, Muriel Darnaudéry, Hélène Louvart, Christel Vanbesien-Mailliot, Assia Catalani, Stefania Maccari.
Psychoneuroendocrinology. 2006-07-01. 31(6) : 769-780.
10.1016/j.psyneuen.2006.02.007 -
Effects of a single footshock followed by situational reminders on HPA axis and behaviour in the aversive context in male and female rats
H LOUVART, S MACCARI, J LESAGE, M LEONHARDT, A DICKESCOOPMAN, M DARNAUDERY.
Psychoneuroendocrinology. 2006-01-01. 31(1) : 92-99.
10.1016/j.psyneuen.2005.05.014 -
Insulin-like growth factor 1 reduces age-related disorders induced by prenatal stress in female rats
Muriel Darnaudéry, Margarita Perez-Martin, Guylaine Bélizaire, Stefania Maccari, Luis Miguel Garcia-Segura.
Neurobiology of Aging. 2006-01-01. 27(1) : 119-127.
10.1016/j.neurobiolaging.2005.01.008 -
Long-term behavioural alterations in female rats after a single intense footshock followed by situational reminders
Hélène Louvart, Stefania Maccari, François Ducrocq, Pierre Thomas, Muriel Darnaudéry.
Psychoneuroendocrinology. 2005-05-01. 30(4) : 316-324.
10.1016/j.psyneuen.2004.09.003 -
Prenatal stress affects behavioral reactivity to an intense stress in adult female rats
Hélène Louvart, Stefania Maccari, Muriel Darnaudéry.
Brain Research. 2005-01-01. 1031(1) : 67-73.
10.1016/j.brainres.2004.10.025 -
Chronic treatment with imipramine reverses immobility behaviour, hippocampal corticosteroid receptors and cortical 5-HT1A receptor mRNA in prenatally stressed rats
S. Morley-Fletcher, M. Darnaudéry, E. Mocaer, N. Froger, L. Lanfumey, G. Laviola, P. Casolini, A.R. Zuena, Lorenzo Marzano, M. Hamon, S. Maccari.
Neuropharmacology. 2004-11-01. 47(6) : 841-847.
10.1016/j.neuropharm.2004.06.011 -
Stress during gestation induces lasting effects on emotional reactivity of the dam rat
Muriel Darnaudéry, Isabelle Dutriez, Odile Viltart, Sara Morley-Fletcher, Stefania Maccari.
Behavioural Brain Research. 2004-08-01. 153(1) : 211-216.
10.1016/j.bbr.2003.12.001 -
Early and later adoptions differently modify mother-pup interactions
Muriel Darnaudéry, Muriel Koehl, Arnaud Barbazanges, Simona Cabib, Michel Le Moal, Stefania Maccari.
Behavioral Neuroscience. 2004-01-01. 118(3) : 590-596.
10.1037/0735-7044.118.3.590 -
Prenatal stress in rats predicts immobility behavior in the forced swim test
S. Morley-Fletcher, M. Darnaudery, M. Koehl, P. Casolini, O. Van Reeth, S. Maccari.
Brain Research. 2003-11-01. 989(2) : 246-251.
10.1016/s0006-8993(03)03293-1 -
Individual differences in cognitive aging: implication of pregnenolone sulfate.
Willy Mayo, Olivier George, Sonia Darbra, Jean-Jacques Bouyer, Monique Vallée, Muriel Darnaudéry, Marc Pallarès, Valérie Lemaire-Mayo, Michel Le Moal, Pier-Vincenzo Piazza, Nora Abrous.
Progress in Neurobiology. 2003-09-01. 71(1) : 43-48.
10.1016/j.pneurobio.2003.09.006 -
Prenatal stress and long-term consequences: implications of glucocorticoid hormones
S. Maccari, M. Darnaudery, S. Morley-Fletcher, A.R. Zuena, C. Cinque, O. Van Reeth.
Neuroscience & Biobehavioral Reviews. 2003-01-01. 27(1-2) : 119-127.
10.1016/s0149-7634(03)00014-9 -
The Neurosteroid Pregnenolone Sulfate Increases Cortical Acetylcholine Release: A Microdialysis Study in Freely Moving Rats
Muriel Darnaudéry, Muriel Koehl, Marc Pallarés, Michel Le Moal, Willy Mayo.
Journal of Neurochemistry. 2002-11-13. 71(5) : 2018-2022.
10.1046/j.1471-4159.1998.71052018.x -
Reliability of high and low anxiety-related behaviour:
Nicolas Salomé, Odile Viltart, Muriel Darnaudéry, Peter Salchner, Nicolas Singewald, Rainer Landgraf, Henrique Sequeira, Alexandra Wigger.
Behavioural Brain Research. 2002-10-01. 136(1) : 227-237.
10.1016/s0166-4328(02)00135-3 -
Reliability of high and low anxiety-related behaviour: influence of laboratory environment and multifactorial analysis.
Nicolas Salomé, Odile Viltart, Muriel Darnaudéry, Peter Salchner, Nicolas Singewald, Rainer Landgraf, Henrique Sequeira, Alexandra Wigger.
Behavioural Brain Research. 2002-10-01. 136(1) : 227-237.
10.1016/s0166-4328(02)00135-3 -
The neurosteroid pregnenolone sulfate infused into the medial septum nucleus increases hippocampal acetylcholine and spatial memory in rats
Muriel Darnaudéry, Marc Pallarès, Pier-Vincenzo Piazza, Michel Le Moal, Willy Mayo.
Brain Research. 2002-10-01. 951(2) : 237-242.
10.1016/s0006-8993(02)03166-9 -
Study of the addictive potential of modafinil in naive and cocaine-experienced rats.
Deroche-Gamonet V., Darnaudéry M., Bruins-Slot L., Piat F., M. Le Moal, Piazza P..
Psychopharmacology. 2002-06-01. 161(4) : 387-395.
10.1007/s00213-002-1080-8 -
The effect of restraint stress on paradoxical sleep is influenced by the circadian cycle
M. Koehl, J.J. Bouyer, M. Darnaudéry, M. Le Moal, W. Mayo.
Brain Research. 2002-05-01. 937(1-2) : 45-50.
10.1016/s0006-8993(02)02463-0 -
Hormonal and Behavioural Abnormalities Induced by Stressin utero: an Animal Model for Depression
S. Maccari, M. Darnaudery, O. Van Reeth.
Stress. 2001-01-01. 4(3) : 169-181.
10.3109/10253890109035016 -
Pregnenolone sulfate increases hippocampal acetylcholine release and spatial recognition
Muriel Darnaudéry, Muriel Koehl, Pier-Vincenzo Piazza, Michel Le Moal, Willy Mayo.
Brain Research. 2000-01-01. 852(1) : 173-179.
10.1016/s0006-8993(99)01964-2 -
Infusion of neurosteroids into the rat nucleus basalis affects paradoxical sleep in accordance with their memory modulating properties
M. Darnaudéry, M. Pallarés, J.J. Bouyer, M. Le Moal, W. Mayo.
Neuroscience. 1999-05-01. 92(2) : 583-588.
10.1016/s0306-4522(99)00019-6 -
Prenatal stress alters circadian activity of hypothalamo-pituitary-adrenal axis and hippocampal corticosteroid receptors in adult rats of both gender
.
Journal of Neurobiology. 1999-09-01. 40(3) : 302-315.
10.1002/(sici)1097-4695(19990905)40:3<302::aid-neu3>3.0.co;2-7 -
The promnesic neurosteroid pregnenolone sulfate increases paradoxical sleep in rats
Muriel Darnaudéry, Jean-Jacques Bouyer, Marc Pallarés, Michel Le Moal, Willy Mayo.
Brain Research. 1999-02-01. 818(2) : 492-498.
10.1016/s0006-8993(98)01338-9 -
Neurosteroids
Willy Mayo, Monique Vallée, Muriel Darnaudéry, Michel Le Moal.
Neurosteroids. 1999-01-01. : 317-335.
10.1007/978-1-59259-693-5_18 -
The neurosteroid pregnenolone sulfate infused into the nucleus basalis increases both acetylcholine release in the frontal cortex or amygdala and spatial memory
M. Pallarés, M. Darnaudéry, J. Day, M. Le Moal, W. Mayo.
Neuroscience. 1998-08-01. 87(3) : 551-558.
10.1016/s0306-4522(98)00174-2 -
Neurosteroids: Deficient cognitive performance in aged rats depends on Low pregnenolone sulfate levels in the hippocampus
M. Vallee, W. Mayo, M. Darnaudery, C. Corpechot, J. Young, M. Koehl, M. Le Moal, E.-E. Baulieu, P. Robel, H. Simon.
Proceedings of the National Academy of Sciences. 1997-12-23. 94(26) : 14865-14870.
10.1073/pnas.94.26.14865 -
Decrease in highly polysialylated neuronal cell adhesion molecules and in spatial learning during ageing are not correlated
D.N. Abrous, M.F. Montaron, K.G. Petry, G. Rougon, M. Darnaudery, M. Le Moal, W. Mayo.
Brain Research. 1997-01-01. 744(2) : 285-292.
10.1016/s0006-8993(96)01115-8