Marc Deffains

Scientific articles

• Dichotomous activity and function of neurons with low- and high-frequency discharge in the external globus pallidus of non-human primates
  Shiran Katabi, Avital Adler, Marc Deffains, Hagai Bergman.
  Cell Reports. 2023-01-01. : 111898.
  10.1016/j.celrep.2022.111898
• Modulation of dopamine tone induces frequency shifts in cortico-basal ganglia beta oscillations
  L. Iskhakova, P. Rappel, M. Deffains, G. Fonar, O. Marmor, R. Paz, Z. Israel, R. Eitan, H. Bergman.
  Nat Commun. 2021-12-02. 12(1)
  10.1038/s41467-021-27375-5
• Striatal and cerebellar vesicular acetylcholine transporter expression is disrupted in human DYT1 dystonia.
  Joachim Mazere, Bixente Dilharreguy, Gwenaëlle Catheline, Marie Vidailhet, Marc Deffains, Delphine Vimont, Bastien Ribot, Elodie Barse, Laura Cif, Bernard Mazoyer, Nicolas Langbour, Antonio Pisani, Michèle Allard, Frédéric Lamare, Dominique Guehl, Philippe Fernandez, Pierre Burbaud.
  Brain. 2021-02-26. 144(3) : 909-923.
  10.1093/brain/awaa465
• The adaptive value of probability distortion and risk-seeking in macaques’ decision-making
  A. Nioche, N. P. Rougier, M. Deffains, S. Bourgeois-Gironde, S. Ballesta, T. Boraud.
  Phil. Trans. R. Soc. B. 2021-01-11. 376(1819) : 20190668.
  10.1098/rstb.2019.0668
• L‐DOPA regulates α‐synuclein accumulation in experimental parkinsonism
  Marc Deffains, Marie‐Hélène Canron, Margaux Teil, Qin Li, Benjamin Dehay, Erwan Bezard, Pierre‐Olivier Fernagut.
  Neuropathol Appl Neurobiol. 2020-12-04.
  10.1111/nan.12678
• What is the true discharge rate and pattern of the striatal projection neurons in Parkinson’s disease and Dystonia?
  Dan Valsky, Shai Heiman Grosberg, Zvi Israel, Thomas Boraud, Hagai Bergman, Marc Deffains.
  eLife. 2020-08-19. 9
  10.7554/elife.57445
• Acute Striato-Cortical Synchronization Induces Focal Motor Seizures in Primates
  Jerome Aupy, Bastien Ribot, Sandra Dovero, Nathalie Biendon, Tho-Hai Nguyen, Gregory Porras, Marc Deffains, Dominique Guehl, Pierre Burbaud.
  Cerebral Cortex. 2020-08-08.
  10.1093/cercor/bhaa212
• Basal ganglia beta oscillations during sleep underlie Parkinsonian insomnia
  Aviv D. Mizrahi-Kliger, Alexander Kaplan, Zvi Israel, Marc Deffains, Hagai Bergman.
  Proc. Natl. Acad. Sci. U.S.A.. 2020-07-07. 117(29) : 17359-17368.
  10.1073/pnas.2001560117
• In vivo electrophysiological validation of DREADD-based modulation of pallidal neurons in the non-human primate.
  Marc Deffains, Tho Haï Nguyen, Hugues Orignac, Nathalie Biendon, Sandra Dovero, Erwan Bezard, Thomas Boraud.
  Eur J Neurosci. 2020-05-11.
  10.1111/ejn.14746
• Parkinsonism-related β oscillations in the primate basal ganglia networks – Recent advances and clinical implications
  Marc Deffains, Hagai Bergman.
  Parkinsonism & Related Disorders. 2019-02-01. 59 : 2-8.
  10.1016/j.parkreldis.2018.12.015
• Longer β oscillatory episodes reliably identify pathological subthalamic activity in Parkinsonism
  Marc Deffains, Liliya Iskhakova, Shiran Katabi, Zvi Israel, Hagai Bergman.
  Mov Disord.. 2018-08-25. 33(10) : 1609-1618.
  10.1002/mds.27418
• Anesthesia reduces discharge rates in the human pallidum without changing the discharge rate ratio between pallidal segments
  Anna Castrioto, Odeya Marmor, Marc Deffains, Dafna Willner, Eduard Linetsky, Hagai Bergman, Zvi Israel, Renana Eitan, David Arkadir.
  Eur J Neurosci. 2016-10-13. 44(11) : 2909-2913.
  10.1111/ejn.13417
• Stop! border ahead: Automatic detection of subthalamic exit during deep brain stimulation surgery
  Dan Valsky, Odeya Marmor-Levin, Marc Deffains, Renana Eitan, Kim T. Blackwell, Hagai Bergman, Zvi Israel.
  Mov Disord.. 2016-10-06. 32(1) : 70-79.
  10.1002/mds.26806
• Subthalamic, not striatal, activity correlates with basal ganglia downstream activity in normal and parkinsonian monkeys
  Marc Deffains, Liliya Iskhakova, Shiran Katabi, Suzanne N Haber, Zvi Israel, Hagai Bergman.
  eLife. 2016-08-23. 5
  10.7554/elife.16443
• Stop and Think about Basal Ganglia Functional Organization: The Pallido-Striatal “Stop” Route
  Marc Deffains, Liliya Iskhakova, Hagai Bergman.
  Neuron. 2016-01-01. 89(2) : 237-239.
  10.1016/j.neuron.2016.01.003
• Striatal cholinergic interneurons and cortico-striatal synaptic plasticity in health and disease
  Marc Deffains, Hagai Bergman.
  Mov Disord.. 2015-06-22. 30(8) : 1014-1025.
  10.1002/mds.26300
• Coinciding Decreases in Discharge Rate Suggest That Spontaneous Pauses in Firing of External Pallidum Neurons Are Network Driven
  E. Schechtman, A. Adler, M. Deffains, H. Gabbay, S. Katabi, A. Mizrahi, H. Bergman.
  Journal of Neuroscience. 2015-04-29. 35(17) : 6744-6751.
  10.1523/jneurosci.5232-14.2015
• Higher neuronal discharge rate in the motor area of the subthalamic nucleus of Parkinsonian patients
  Marc Deffains, Peter Holland, Shay Moshel, Fernando Ramirez de Noriega, Hagai Bergman, Zvi Israel.
  Journal of Neurophysiology. 2014-09-15. 112(6) : 1409-1420.
  10.1152/jn.00170.2014
• Importance of the temporal structure of movement sequences on the ability of monkeys to use serial order information
  Marc Deffains, Eric Legallet, Paul Apicella.
  Exp Brain Res. 2011-08-20. 214(3) : 415-425.
  10.1007/s00221-011-2839-0
• The Role of Striatal Tonically Active Neurons in Reward Prediction Error Signaling during Instrumental Task Performance
  P. Apicella, S. Ravel, M. Deffains, E. Legallet.
  Journal of Neuroscience. 2011-01-26. 31(4) : 1507-1515.
  10.1523/jneurosci.4880-10.2011
• Modulation of Neuronal Activity in the Monkey Putamen Associated With Changes in the Habitual Order of Sequential Movements
  Marc Deffains, Eric Legallet, Paul Apicella.
  Journal of Neurophysiology. 2010-09-01. 104(3) : 1355-1369.
  10.1152/jn.00355.2010
• Tonically active neurons in the striatum differentiate between delivery and omission of expected reward in a probabilistic task context
  Paul Apicella, Marc Deffains, Sabrina Ravel, Eric Legallet.
  European Journal of Neuroscience. 2009-08-01. 30(3) : 515-526.
  10.1111/j.1460-9568.2009.06872.x