Erwan Bezard

Scientific articles

• Encoding social preference by interhemispheric neurons in the Insula
  Christelle Glangetas, Elodie Ladevèze, Adriane Guillaumin, Manon Gauthier, Evelyne Doudnikoff, Erwan Bézard, Anne Taupignon, Jérôme Baufreton, François Georges.
  . 2022-12-15.
  10.1101/2022.12.15.520538
• Tau seeds from patients induce progressive supranuclear palsy pathology and symptoms in primates
  Morgane Darricau, Taxiarchis Katsinelos, Flavio Raschella, Tomislav Milekovic, Louis Crochemore, Qin Li, Grégoire Courtine, William A McEwan, Benjamin Dehay, Erwan Bezard, Vincent Planche.
  Brain. 2022-11-16.
  10.1093/brain/awac428
• A Novel C-Type Lectin Receptor-Targeted α-Synuclein-Based Parkinson Vaccine Induces Potent Immune Responses and Therapeutic Efficacy in Mice
  Sabine Schmidhuber, Sandra Scheiblhofer, Richard Weiss, Mihály Cserepes, József Tóvári, Gabriele Gadermaier, Erwan Bezard, Francesca De Giorgi, Francois Ichas, Dirk Strunk, Markus Mandler.
  Vaccines. 2022-08-30. 10(9) : 1432.
  10.3390/vaccines10091432
• The Zinc Ionophore Clioquinol Reduces Parkinson’s Disease Patient-Derived Brain Extracts-Induced Neurodegeneration
  Margaux Teil, Evelyne Doudnikoff, Marie-Laure Thiolat, Sylvain Bohic, Erwan Bezard, Benjamin Dehay.
  Mol Neurobiol. 2022-08-02.
  10.1007/s12035-022-02974-5
• Acidic nanoparticles protect against α-synuclein-induced neurodegeneration through the restoration of lysosomal function.
  Arotcarena ML, Soria FN, Cunha A, Doudnikoff E, Prévot G, Daniel J, Blanchard-Desce M, Barthélémy P, Bezard E, Crauste-Manciet S, Dehay B..
  Aging cell. .
  10.1111/acel.13584
• Basal ganglia neuropeptides show abnormal processing associated with L-DOPA-induced dyskinesia
  Heather Hulme, Elva Fridjonsdottir, Theodosia Vallianatou, Reza Shariatgorji, Anna Nilsson, Qin Li, Erwan Bezard, Per E. Andrén.
  npj Parkinsons Dis.. 2022-04-13. 8(1)
  10.1038/s41531-022-00299-7
• Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology
  Margaux Teil, Sandra Dovero, Mathieu Bourdenx, Marie-Laure Arotcarena, Sandrine Camus, Gregory Porras, Marie-Laure Thiolat, Ines Trigo-Damas, Celine Perier, Cristina Estrada, Nuria Garcia-Carrillo, Michele Morari, Wassilios G Meissner, María Trinidad Herrero, Miquel Vila, Jose A Obeso, Erwan Bezard, Benjamin Dehay.
  Brain. 2022-03-14. 145(3) : 1001-1017.
  10.1093/brain/awab374
• Neurons with Cat’s Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions
  Francesca De Giorgi, Muhammed Bilal Abdul-Shukkoor, Marianna Kashyrina, Leslie-Ann Largitte, Francesco De Nuccio, Brice Kauffmann, Alons Lends, Florent Laferrière, Sébastien Bonhommeau, Dario Domenico Lofrumento, Luc Bousset, Erwan Bezard, Thierry Buffeteau, Antoine Loquet, François Ichas.
  Biomolecules. 2022-03-11. 12(3) : 436.
  10.3390/biom12030436
• Striatal synaptic bioenergetic and autophagic decline in premotor experimental parkinsonism
  Leyre Merino-Galan, Haritz Jimenez-Urbieta, Marta Zamarbide, Tatiana Rodríguez-Chinchilla, Arantzazu Belloso-Iguerategui, Enrique Santamaria, Joaquín Fernández-Irigoyen, Ana Aiastui, Evelyne Doudnikoff, Erwan Bézard, Alberto Ouro, Shira Knafo, Belén Gago, Ana Quiroga-Varela, María Cruz Rodríguez-Oroz.
  Brain. 2022-03-04.
  10.1093/brain/awac087
• How Lazy Reading and Semantic Sloppiness May Harm Progress in Synucleinopathy Research
  Erwan Bezard.
  Biomolecules. 2022-01-28. 12(2) : 228.
  10.3390/biom12020228
• Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson’s disease
  Florent Laferrière, Stéphane Claverol, Erwan Bezard, Francesca De Giorgi, François Ichas.
  npj Parkinsons Dis.. 2022-01-13. 8(1)
  10.1038/s41531-021-00264-w
• Maladie de Parkinson
  Erwan Bezard, Benjamin Dehay.
  Med Sci (Paris). 2022-01-01. 38(1) : 45-51.
  10.1051/medsci/2021241
• Motor and non-motor circuit disturbances in early Parkinson disease: which happens first?
  Javier Blesa, Guglielmo Foffani, Benjamin Dehay, Erwan Bezard, Jose A. Obeso.
  Nat Rev Neurosci. 2021-12-14.
  10.1038/s41583-021-00542-9
• Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques
  Marie-Laure Arotcarena, Sandra Dovero, Nathalie Biendon, Nathalie Dutheil, Vincent Planche, Erwan Bezard, Benjamin Dehay.
  Front. Bioeng. Biotechnol.. 2021-11-15. 9
  10.3389/fbioe.2021.762209
• Lack of limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes in aged macaques with memory impairment
  Morgane Darricau, Marie-Hélène Canron, Marion Bosc, Marie-Laure Arotçarena, Mégane Le Quang, Benjamin Dehay, Erwan Bezard, Vincent Planche.
  Neurobiology of Aging. 2021-11-01. 107 : 53-56.
  10.1016/j.neurobiolaging.2021.07.009
• Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson’s disease and L-Dopa induced dyskinesia
  Lauren Malave, Dustin R. Zuelke, Santiago Uribe-Cano, Lev Starikov, Heike Rebholz, Eitan Friedman, Chuan Qin, Qin Li, Erwan Bezard, Andreas H. Kottmann.
  Commun Biol. 2021-09-22. 4(1)
  10.1038/s42003-021-02567-3
• Impaired brain insulin signalling in Parkinson’s disease
  Fares Bassil, Anna Delamarre, Marie‐Helene Canron, Nathalie Dutheil, Anne Vital, Marie‐Laure Négrier‐Leibreich, Erwan Bezard, Pierre‐Olivier Fernagut, Wassilios G. Meissner.
  Neuropathol Appl Neurobiol. 2021-08-17.
  10.1111/nan.12760
• Similar neuronal imprint and absence of cross-seeded partner fibrils in α-synuclein aggregates from MSA and Parkinson’s disease brains
  Florent Laferrière, Stéphane Claverol, Erwan Bezard, Francesca De Giorgi, François Ichas.
  Preprint bioRxiv. 2021-06-22.
  10.1101/2021.06.22.449410
• Adenosine A_2AR/A₁R Antagonists Enabling Additional H₃R Antagonism for the Treatment of Parkinson’s Disease.
  Stefanie Hagenow, Anna Affini, Elsa Y. Pioli, Sonja Hinz, Yan Zhao, Gregory Porras, Vigneshwaran Namasivayam, Christa E. Müller, Jian-Sheng Lin, Erwan Bezard, Holger Stark.
  J. Med. Chem.. 2021-06-09.
  10.1021/acs.jmedchem.0c00914
• Amyloid beta oligomers modulate neuronal autophagy through the primary cilium
  Olatz Pampliega, Federico N. Soria, Narayana Pineda-Ramírez, Erwan Bezard.
  Preprint bioRxiv. 2021-06-02.
  10.1101/2021.06.02.446758
• Comparison of the expression and toxicity of AAV2/9 carrying the human A53T α-synuclein gene in presence or absence of WPRE
  Xiuping Sun, Xuan Yu, Ling Zhang, Wenjie Zhao, Manshi Wang, Yu Zhang, Xianglei Li, Ran Gao, Ludivine S. Breger, Sandra Dovero, Gregory Porras, Pierre-Olivier Fernagut, Benjamin Dehay, Erwan Bezard, Chuan Qin.
  Heliyon. 2021-02-01. 7(2) : e06302.
  10.1016/j.heliyon.2021.e06302
• Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury
  J. W. Squair, M. Gautier, L. Mahe, J.E. Soriano, A Rowald, A. Bichat, N. Cho, M. A. Anderson, N. D. James, J. Gandar, A. V. Incognito, G. Schiavone, Z. K. Sarafis, A. Laskaratos, K. Bartholdi, R. Demesmaeker, S. Komi, C. Moerman, B. Vaseghi, B. Scott, R. Rosentreter, C. Kathe, J. Ravier, L. McCracken, X. Kang, N. Vachicouras, F. Fallegger, I. Jelescu, Y. Cheng, Q. Li, R. Buschman, N. Buse, T. Denison, S. Dukelow, R. Charbonneau, I. Rigby, S. K. Boyd, P.J. Millar, E. M. Moraud, M. Capogrosso, F. B. Wagner, Q. Barraud, E. Bezard, S. P. Lacour, J. Bloch, G. Courtine, A. A. Phillips.
  Nature. 2021-01-27.
  10.1038/s41586-020-03180-w
• Involvement of Autophagy in Levodopa‐Induced Dyskinesia
  Michael Feyder, Carina Plewnia, Ori J. Lieberman, Giada Spigolon, Alessandro Piccin, Lidia Urbina, Benjamin Dehay, Qin Li, Per Nilsson, Mikael Altun, Emanuela Santini, David Sulzer, Erwan Bezard, Anders Borgkvist, Gilberto Fisone.
  Mov Disord. 2021-01-18.
  10.1002/mds.28480
• Mass spectrometry imaging identifies abnormally elevated brain l -DOPA levels and extrastriatal monoaminergic dysregulation in l -DOPA–induced dyskinesia
  Elva Fridjonsdottir, Reza Shariatgorji, Anna Nilsson, Theodosia Vallianatou, Luke R. Odell, Luke S. Schembri, Per Svenningsson, Pierre-Olivier Fernagut, Alan R. Crossman, Erwan Bezard, Per E. Andrén.
  Sci. Adv.. 2021-01-06. 7(2)
  10.1126/sciadv.abe5948
• Evaluation of blood flow as a route for propagation in experimental synucleinopathy
  Xuan Yu, Marine Persillet, Ling Zhang, Yu Zhang, Sun Xiuping, Xianglei Li, Gao Ran, Ludivine S. Breger, Sandra Dovero, Gregory Porras, Benjamin Dehay, Erwan Bezard, Chuan Qin.
  Neurobiology of Disease. 2021-01-01. : 105255.
  10.1016/j.nbd.2021.105255
• Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease.
  David J. Marmion, Angela A. Rutkowski, Diptaman Chatterjee, Benjamin M. Hiller, Milton H. Werner, Erwan Bezard, Deniz Kirik, Thomas McCown, Steven J. Gray, Jeffrey H. Kordower.
  Neurobiology of Disease. 2021-01-01. 148 : 105184.
  10.1016/j.nbd.2020.105184
• Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA–induced dyskinesia
  Elva Fridjonsdottir, Reza Shariatgorji, Anna Nilsson, Theodosia Vallianatou, Luke R. Odell, Luke S. Schembri, Per Svenningsson, Pierre-Olivier Fernagut, Alan R. Crossman, Erwan Bezard, Per E. Andrén.
  Sci. Adv.. 2021-01-01. 7(2) : eabe5948.
  10.1126/sciadv.abe5948
• L‐DOPA regulates α‐synuclein accumulation in experimental parkinsonism
  Marc Deffains, Marie‐Hélène Canron, Margaux Teil, Qin Li, Benjamin Dehay, Erwan Bezard, Pierre‐Olivier Fernagut.
  Neuropathol Appl Neurobiol. 2020-12-04.
  10.1111/nan.12678
• Gastrointestinal and metabolic function in the MPTP-treated macaque model of Parkinson’s disease
  Anna Delamarre, Cliona MacSweeney, Rie Suzuki, Alastair JH. Brown, Qin Li, Elsa Y. Pioli, Erwan Bezard.
  Heliyon. 2020-12-01. 6(12) : e05771.
  10.1016/j.heliyon.2020.e05771
• From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson’s Disease.
  Tiago F. Outeiro, Peter Heutink, Erwan Bezard, Angela M. Cenci.
  Mov Disord. 2020-11-16.
  10.1002/mds.28387
• Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy
  Florent Laferrière, Xin He, Federica Zinghirino, Evelyne Doudnikoff, Emilie Faggiani, Wassilios G. Meissner, Erwan Bezard, Francesca De Giorgi, François Ichas.
  Cells. 2020-10-29. 9(11) : 2371.
  10.3390/cells9112371
• Corrigendum: Low-Dimensional Motor Cortex Dynamics Preserve Kinematics Information During Unconstrained Locomotion in Nonhuman Primates.
  David Xing, Mehdi Aghagolzadeh, Wilson Truccolo, Erwan Bezard, Gregoire Courtine, David Borton.
  Front. Neurosci.. 2020-10-29. 14
  10.3389/fnins.2020.604517
• Novel self-replicating α-synuclein polymorphs that escape ThT monitoring can spontaneously emerge and acutely spread in neurons
  Francesca De Giorgi, Florent Laferrière, Federica Zinghirino, Emilie Faggiani, Alons Lends, Mathilde Bertoni, Xuan Yu, Axelle Grélard, Estelle Morvan, Birgit Habenstein, Nathalie Dutheil, Evelyne Doudnikoff, Jonathan Daniel, Stéphane Claverol, Chuan Qin, Antoine Loquet, Erwan Bezard, François Ichas.
  Sci. Adv.. 2020-10-01. 6(40) : eabc4364.
  10.1126/sciadv.abc4364
• CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease
  Nora Bengoa-Vergniory, Emilie Faggiani, Paula Ramos-Gonzalez, Ecem Kirkiz, Natalie Connor-Robson, Liam V. Brown, Ibrar Siddique, Zizheng Li, Siv Vingill, Milena Cioroch, Fabio Cavaliere, Sarah Threlfell, Bradley Roberts, Thomas Schrader, Frank-Gerrit Klärner, Stephanie Cragg, Benjamin Dehay, Gal Bitan, Carlos Matute, Erwan Bezard, Richard Wade-Martins.
  Nat Commun. 2020-09-28. 11(1)
  10.1038/s41467-020-18689-x
• µ opioid receptor agonism for L-DOPA-induced dyskinesia in Parkinson’s disease
  Erwan Bezard, Qin Li, Heather Hulme, Elva Fridjonsdottir, Anna Nilsson, Elsa Pioli, Per E. Andren, Alan R. Crossman.
  J. Neurosci.. 2020-07-20. : JN-RM-0610-20.
  10.1523/JNEUROSCI.0610-20.2020
• Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
  Federico N. Soria, Chiara Paviolo, Evelyne Doudnikoff, Marie-Laure Arotcarena, Antony Lee, Noémie Danné, Amit Kumar Mandal, Philippe Gosset, Benjamin Dehay, Laurent Groc, Laurent Cognet, Erwan Bezard.
  Nat Commun. 2020-07-10. 11(1)
  10.1038/s41467-020-17328-9
• Intraventricular dopamine infusion alleviates motor symptoms in a primate model of Parkinson’s disease.
  Caroline Moreau, Anne Sophie Rolland, Elsa Pioli, Qin Li, Pascal Odou, Christine Barthelemy, Damien Lannoy, Alexandre Demailly, Natacha Carta, Vincent Deramecourt, Florent Auger, Gregory Kuchcinski, Charlotte Laloux, Luc Defebvre, Regis Bordet, James Duce, Jean Christophe Devedjian, Erwan Bezard, Matthieu Fisichella, David Devos.
  Neurobiology of Disease. 2020-06-01. 139 : 104846.
  10.1016/j.nbd.2020.104846
• Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson’s disease.
  Fanny Faivre, María-José Sánchez-Catalán, Sandra Dovero, Simone Bido, Anil Joshi, Erwan Bezard, Michel Barrot.
  Neurobiology of Disease. 2020-06-01. 139 : 104818.
  10.1016/j.nbd.2020.104818
• In vivo electrophysiological validation of DREADD-based modulation of pallidal neurons in the non-human primate.
  Marc Deffains, Tho Haï Nguyen, Hugues Orignac, Nathalie Biendon, Sandra Dovero, Erwan Bezard, Thomas Boraud.
  Eur J Neurosci. 2020-05-11.
  10.1111/ejn.14746
• Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates
  Marie-Laure Arotcarena, Sandra Dovero, Alice Prigent, Mathieu Bourdenx, Sandrine Camus, Gregory Porras, Marie-Laure Thiolat, Maddalena Tasselli, Philippe Aubert, Niels Kruse, Brit Mollenhauer, Ines Trigo Damas, Cristina Estrada, Nuria Garcia-Carrillo, Nishant N Vaikath, Omar M A El-Agnaf, Maria Trinidad Herrero, Miquel Vila, Jose A Obeso, Pascal Derkinderen, Benjamin Dehay, Erwan Bezard.
  Brain. 2020-05-01. 143(5) : 1462-1475.
  10.1093/brain/awaa096
• Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates
  Philippe Gosset, Alexander Maxan, Melanie Alpaugh, Ludivine Breger, Benjamin Dehay, Zhu Tao, Zhang Ling, Chuan Qin, Giulia Cisbani, Nadia Fortin, Jean-Paul G. Vonsattel, Steve Lacroix, Abid Oueslati, Erwan Bezard, Francesca Cicchetti.
  Neurobiology of Disease. 2020-05-01. : 104941.
  10.1016/j.nbd.2020.104941
• Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
  M. Bourdenx, A. Nioche, S. Dovero, M.-L. Arotcarena, S. Camus, G. Porras, M.-L. Thiolat, N. P. Rougier, A. Prigent, P. Aubert, S. Bohic, C. Sandt, F. Laferrière, E. Doudnikoff, N. Kruse, B. Mollenhauer, S. Novello, M. Morari, T. Leste-Lasserre, I. Trigo Damas, M. Goillandeau, C. Perier, C. Estrada, N. Garcia-Carrillo, A. Recasens, N. N. Vaikath, O. M. A. El-Agnaf, M. T. Herrero, P. Derkinderen, M. Vila, J. A. Obeso, B. Dehay, E. Bezard.
  Sci. Adv.. 2020-05-01. 6(20) : eaaz9165.
  10.1126/sciadv.aaz9165
• RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson’s disease.
  Mehdi Eshraghi, Uri Nimrod Ramírez-Jarquín, Neelam Shahani, Tommaso Nuzzo, Arianna De Rosa, Supriya Swarnkar, Nicole Galli, Oscar Rivera, George Tsaprailis, Catherina Scharager-Tapia, Gogce Crynen, Qin Li, Marie-Laure Thiolat, Erwan Bezard, Alessandro Usiello, Srinivasa Subramaniam.
  Sci. Adv.. 2020-05-01. 6(18) : eaaz7001.
  10.1126/sciadv.aaz7001
• Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates
  Alexander Maxan, Giacomo Sciacca, Melanie Alpaugh, Zhu Tao, Ludivine Breger, Benjamin Dehay, Zhang Ling, Chuan Qin, Giulia Cisbani, Maria Masnata, Shireen Salem, Steve Lacroix, Abid Oueslati, Erwan Bezard, Francesca Cicchetti.
  Neurobiology of Disease. 2020-05-01. : 104951.
  10.1016/j.nbd.2020.104951
• Nilotinib Fails to Prevent Synucleinopathy and Cell Loss in a Mouse Model of Multiple System Atrophy
  Miguel Lopez-Cuina, Paul A. Guerin, Marie-Hélène Canron, Anna Delamarre, Benjamin Dehay, Erwan Bezard, Wassilios G. Meissner, Pierre-Olivier Fernagut.
  Mov Disord. 2020-04-14.
  10.1002/mds.28034
• Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy.
  Heather Hulme, Elva Fridjonsdottir, Halla Gunnarsdottir, Theodosia Vallianatou, Xiaoqun Zhang, Henrik Wadensten, Reza Shariatgorji, Anna Nilsson, Erwan Bezard, Per Svenningsson, Per E. Andrén.
  Neurobiology of Disease. 2020-04-01. 137 : 104738.
  10.1016/j.nbd.2020.104738
• Soft, Implantable Bioelectronic Interfaces for Translational Research.
  Giuseppe Schiavone, Florian Fallegger, Xiaoyang Kang, Beatrice Barra, Nicolas Vachicouras, Evgenia Roussinova, Ivan Furfaro, Sébastien Jiguet, Ismael Seáñez, Simon Borgognon, Andreas Rowald, Qin Li, Chuan Qin, Erwan Bézard, Jocelyne Bloch, Grégoire Courtine, Marco Capogrosso, Stéphanie P. Lacour.
  Adv. Mater.. 2020-03-16. 32(17) : 1906512.
  10.1002/adma.201906512
• Dopaminergic Co-transmission with Sonic Hedgehog Inhibits Expression of Abnormal Involuntary Movements
  Lauren Malave, Dustin R. Zuelke, Lev Starikov, Heike Rebholz, Eitan Friedman, Chuan Qin, Qin Li, Erwan Bezard, Andreas H. Kottmann.
  . 2020-03-10.
  10.1101/2020.03.09.983759
• Emergence of stealth polymorphs that escape α-synuclein amyloid monitoring, take over and acutely spread in neurons
  Francesca De Giorgi, Florent Laferrière, Federica Zinghirino, Emilie Faggiani, Alons Lends, Mathilde Bertoni, Xuan Yu, Axelle Grélard, Estelle Morvan, Birgit Habenstein, Nathalie Dutheil, Evelyne Doudnikoff, Jonathan Daniel, Stéphane Claverol, Chuan Qin, Antoine Loquet, Erwan Bezard, François Ichas.
  . 2020-02-12.
  10.1101/2020.02.11.943670
• Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice
  Eléonore Bertin, Thomas Deluc, Kjara S. Pilch, Audrey Martinez, Johan-Till Pougnet, Evelyne Doudnikoff, Anne-Emilie Allain, Philine Bergmann, Marion Russeau, Estelle Toulmé, Erwan Bezard, Friedrich Koch-Nolte, Philippe Séguéla, Sabine Lévi, Bruno Bontempi, François Georges, Sandrine S. Bertrand, Olivier Nicole, Eric Boué-Grabot.
  Mol Psychiatry. 2020-01-08.
  10.1038/s41380-019-0641-8
• Parkinsonian Symptoms, Not Dyskinesia, Negatively Affect Active Life Participation of Dyskinetic Patients with Parkinson’s Disease.
  Etienne Goubault, Sarah Bogard, Pierre J. Blanchet, Erwan Bézard, Claude Vincent, Davide Martino, Justyna Sarna, Oury Monchi, Christian Duval.
  Tremor and Other Hyperkinetic Movements. 2020-01-01. 10(1)
  10.5334/tohm.403
• Managing Parkinson’s disease: moving ON with NOP.
  Daniela Mercatelli, Erwan Bezard, Roberto Eleopra, Nurulain T. Zaveri, Michele Morari.
  Br J Pharmacol. 2020-01-01. 177(1) : 28-47.
  10.1111/bph.14893
• Models of hyperkinetic disorders in primates
  Erwan Bezard.
  Journal of Neuroscience Methods. 2019-12-01. : 108551.
  10.1016/j.jneumeth.2019.108551
• Multiple System Atrophy: Recent Developments and Future Perspectives
  Wassilios G. Meissner, Pierre‐Olivier Fernagut, Benjamin Dehay, Patrice Péran, Anne Pavy‐Le Traon, Alexandra Foubert‐Samier, Miguel Lopez Cuina, Erwan Bezard, François Tison, Olivier Rascol.
  Mov Disord. 2019-11-06.
  10.1002/mds.27894
• Dystonia and dopamine: From phenomenology to pathophysiology
  Bastien Ribot, Jérome Aupy, Marie Vidailhet, Joachim Mazère, Antonio Pisani, Erwan Bezard, Dominique Guehl, Pierre Burbaud.
  Progress in Neurobiology. 2019-11-01. 182 : 101678.
  10.1016/j.pneurobio.2019.101678
• Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in non-human primates
  M. Bourdenx, A. Nioche, S. Dovero, M.-L. Arotcarena, S. Camus, G. Porras, M.-L. Thiolat, N. P. Rougier, A. Prigent, P. Aubert, S. Bohic, C. Sandt, F. Laferrière, E. Doudnikoff, N. Kruse, B. Mollenhauer, S. Novello, M. Morari, T. Leste-Lasserre, I. Trigo Damas, M. Goillandeau, C. Perier, C. Estrada, N. Garcia-Carrillo, A. Recasens, N. N. Vaikath, O. M. A. El-Agnaf, M. Trinidad Herrero, P. Derkinderen, M. Vila, J. A. Obeso, B. Dehay, E. Bezard.
  . 2019-10-31.
  10.1101/825216
• Comprehensive mapping of neurotransmitter networks by MALDI–MS imaging
  Mohammadreza Shariatgorji, Anna Nilsson, Elva Fridjonsdottir, Theodosia Vallianatou, Patrik Källback, Luay Katan, Jonas Sävmarker, Ioannis Mantas, Xiaoqun Zhang, Erwan Bezard, Per Svenningsson, Luke R. Odell, Per E. Andrén.
  Nat Methods. 2019-09-23. 16(10) : 1021-1028.
  10.1038/s41592-019-0551-3
• Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies
  Marie-Laure Arotcarena, Mathieu Bourdenx, Nathalie Dutheil, Marie-Laure Thiolat, Evelyne Doudnikoff, Sandra Dovero, Andrea Ballabio, Pierre-Olivier Fernagut, Wassilios G. Meissner, Erwan Bezard, Benjamin Dehay.
  JCI Insight. 2019-08-22. 4(16)
  10.1172/jci.insight.129719
• Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson’s disease.
  Carl Rosenblad, Qin Li, Elsa Y. Pioli, Sandra Dovero, André SLM Antunes, Leticia Agúndez, Martino Bardelli, R. Michael Linden, Els Henckaerts, Anders Björklund, Erwan Bezard, Tomas Björklund.
  Brain. 2019-06-26. 142(8) : 2402-2416.
  10.1093/brain/awz176
• The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson’s disease patients.
  Tommaso Nuzzo, Daniela Punzo, Paola Devoto, Elena Rosini, Silvia Paciotti, Silvia Sacchi, Qin Li, Marie-Laure Thiolat, Celine Véga, Massimo Carella, Manolo Carta, Fabrizio Gardoni, Paolo Calabresi, Loredano Pollegioni, Erwan Bezard, Lucilla Parnetti, Francesco Errico, Alessandro Usiello.
  Sci Rep. 2019-06-20. 9(1)
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• Assessment of plasma creatine kinase as biomarker for levodopa-induced dyskinesia in Parkinson’s disease
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• l-Dopa-free learned dyskinetic behavior in a Parkinson’s primate model.
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• Engrailed-1 induces long-lasting behavior benefit in an experimental Parkinson primate model.
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• Remnants of Cardinal Symptoms of Parkinson’s Disease, Not Dyskinesia, Are Problematic for Dyskinetic Patients Performing Activities of Daily Living.
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• Nanoscale exploration of the extracellular space in the live brain by combining single carbon nanotube tracking and super-resolution imaging analysis
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• Local transgene expression and whole-body transgenesis to model brain diseases in nonhuman primate
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• NMDA receptor GluN2D subunit participates to levodopa-induced dyskinesia pathophysiology
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• The hidden side of Parkinson’s disease: studying pain, anxiety and depression in animal models.
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  Neuroscience & Biobehavioral Reviews. 2019-01-01. 96 : 335-352.
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• TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates.
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• RGS9-2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models.
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• Microdialysis in awake macaque monkeys for central nervous system pharmacokinetics
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• G2019S LRRK2 mutation facilitates α-synuclein neuropathology in aged mice.
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• Levodopa-induced dyskinesia in Parkinson disease: Current and Evolving Concepts.
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• Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-related Neurodegenerative Diseases.
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• The expression of cannabinoid type 1 receptor and 2-arachidonoyl glycerol synthesizing/degrading enzymes is altered in basal ganglia during the active phase of levodopa-induced dyskinesia.
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• Meta-analysis of amantadine efficacy for improving preclinical research reliability.
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• An mGlu4-Positive Allosteric Modulator Alleviates Parkinsonism in Primates.
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• Configuration of electrical spinal cord stimulation through real-time processing of gait kinematics.
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• Configuration of electrical spinal cord stimulation through real-time processing of gait kinematics
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• Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing.
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• Systemic Gene Delivery by Single-Dose Intracardiac Administration of scAAV2/9 and scAAV2/rh10 Variants in Newborn Rats.
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• Cardinal Motor Features of Parkinson’s Disease Coexist with Peak-Dose Choreic-Type Drug-Induced Dyskinesia.
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• Inhaling xenon ameliorates l-dopa-induced dyskinesia in experimental parkinsonism
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• Inhaling xenon ameliorates l-dopa-induced dyskinesia in experimental parkinsonism.
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• The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline.
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  Current Biology. 2018-04-01. 28(7) : 1079-1089.e4.
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• Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson’s Disease Models.
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• Synaptic Regulator α-Synuclein in Dopaminergic Fibers Is Essentially Required for the Maintenance of Subependymal Neural Stem Cells
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• Rabphilin 3A: A novel target for the treatment of levodopa-induced dyskinesias.
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  Neurobiology of Disease. 2017-12-01. 108 : 54-64.
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• Experimental animal models of Parkinson’s disease: A transition from assessing symptomatology to α-synuclein targeted disease modification
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• In utero delivery of rAAV2/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson’s disease.
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• A preclinical study on the combined effects of repeated eltoprazine and preladenant treatment for alleviating L-DOPA-induced dyskinesia in Parkinson’s disease.
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• Past, present, and future of Parkinson’s disease: A special essay on the 200th Anniversary of the Shaking Palsy.
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• Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson’s disease
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• Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies
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  Progress in Neurobiology. 2017-08-01. 155 : 171-193.
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• Decreased Rhes mRNA levels in the brain of patients with Parkinson’s disease and MPTP-treated macaques.
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  PLoS ONE. 2017-07-25. 12(7) : e0181677.
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• Alterations in functional cortical hierarchy in hemiparkinsonian rats.
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• In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains.
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  Neurobiology of Disease. 2017-07-01. 103 : 101-112.
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• U18666A, an activator of sterol regulatory element binding protein pathway, modulates presynaptic dopaminergic phenotype of SH-SY5Y neuroblastoma cells
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  Synapse. 2017-06-20. 71(9) : e21980.
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• Viral-mediated oligodendroglial alpha-synuclein expression models multiple system atrophy.
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• Involvement of the bed nucleus of the stria terminalis in L-Dopa induced dyskinesia
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• Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration.
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  Human Molecular Genetics. 2017-05-17. 26(14) : 2603-2615.
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• Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model.
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• Oral ambroxol increases brain glucocerebrosidase activity in a nonhuman primate.
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• Insulin resistance and exendin-4 treatment for multiple system atrophy.
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  Brain. 2017-03-14. 140(5) : 1420-1436.
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• Impulse control disorders and levodopa-induced dyskinesias in Parkinson’s disease: an update.
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• Impulse control disorders and levodopa-induced dyskinesias in Parkinson’s disease: an update.
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• Exosomes, an Unmasked Culprit in Neurodegenerative Diseases.
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• Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity.
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• Ambroxol effects in glucocerebrosidase and α-synuclein transgenic mice.
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• An evaluation of istradefylline treatment on Parkinsonian motor and cognitive deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque models
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• A brain-spine interface alleviating gait deficits after spinal cord injury in primates.
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• Multi-facetted impulsivity following nigral degeneration and dopamine replacement therapy.
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• LC-MS/MS-based quantification of kynurenine metabolites, tryptophan, monoamines and neopterin in plasma, cerebrospinal fluid and brain.
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• Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy.
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• Is near-infrared light neuroprotective?
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• M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia.
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• MitoBrain, Putting energy into the brain.
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• A Phase 2A Trial of the Novel mGluR5-Negative Allosteric Modulator Dipraglurant for Levodopa-Induced Dyskinesia in Parkinson’s Disease.
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• Permeability of blood-brain barrier in macaque model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson disease.
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• Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA-Induced Dyskinesia.
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• Inhibiting Lateral Habenula Improves L-DOPA-Induced Dyskinesia.
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• Targeting α-synuclein: Therapeutic options.
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• Antidyskinetic effect of A2A and 5HT1A/1B receptor ligands in two animal models of Parkinson’s disease.
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• Spatiotemporal neuromodulation therapies engaging muscle synergies improve motor control after spinal cord injury.
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• Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases.
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• Harnessing the trophic and modulatory potential of statins in a dopaminergic cell line.
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• Striatal NELF-mediated RNA polymerase II stalling controls L-dopa induced dyskinesia.
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• Early prenatal exposure to MPTP does not affect nigrostrial neurons in macaque monkey.
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• Unexpected toxicity of very low dose MPTP in mice: A clue to the etiology of Parkinson’s disease?
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• M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia.
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  Neuron. 2015-11-01. 88(4) : 762-773.
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• Why bother using non-human primate models of cognitive disorders in translational research?
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  Neurobiology of Learning and Memory. 2015-10-01. 124 : 123-129.
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• Alpha-synuclein propagation: New insights from animal models.
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• Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson’s disease.
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• Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates.
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• Targeting α-synuclein for treatment of Parkinson’s disease: mechanistic and therapeutic considerations.
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• Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.
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• Effect of serotonin transporter blockade on L-DOPA-induced dyskinesia in animal models of Parkinson’s disease
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  Neuroscience. 2015-07-01. 298 : 389-396.
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• D1 dopamine receptor stimulation impairs striatal proteasome activity in Parkinsonism through 26S proteasome disassembly.
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  Neurobiology of Disease. 2015-06-01. 78 : 77-87.
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• Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson’s disease.
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• Blood withdrawal affects iron store dynamics in primates with consequences on monoaminergic system function.
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• Could the serotonin theory give rise to a treatment for levodopa-induced dyskinesia in Parkinson’s disease?
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• Wireless neurosensor for full-spectrum electrophysiology recordings during free behavior.
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  Neuron. 2014-12-01. 84(6) : 1170-1182.
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• Direct targeted quantitative molecular imaging of neurotransmitters in brain tissue sections.
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• RGS4 is involved in the generation of abnormal involuntary movements in the unilateral 6-OHDA-lesioned rat model of Parkinson’s disease.
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  Neurobiology of Disease. 2014-10-01. 70 : 138-148.
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• Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology?
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• Down-regulating α-synuclein for treating synucleopathies.
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• Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.
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• Slowing of neurodegeneration in Parkinson’s disease and Huntington’s disease: future therapeutic perspectives.
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• Slowing of neurodegeneration in Parkinson’s disease and Huntington’s disease: future therapeutic perspectives.
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• Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease modification?
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  Progress in Neurobiology. 2014-07-01. 118 : 1-18.
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• Multiple system atrophy: a prototypical synucleinopathy for disease-modifying therapeutic strategies.
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  Neurobiology of Disease. 2014-07-01. 67 : 133-139.
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• Systemic gene delivery to the central nervous system using Adeno-associated virus.
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• The mGluR5 negative allosteric modulator dipraglurant reduces dyskinesia in the MPTP macaque model.
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  Mov Disord.. 2014-05-27. 29(8) : 1074-1079.
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• Widespread Monoaminergic Dysregulation of Both Motor and Non-Motor Circuits in Parkinsonism and Dyskinesia.
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  Cereb. Cortex. 2014-04-25. 25(9) : 2783-2792.
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• Effects of L-tryptophan on L-DOPA-induced dyskinesia in the L-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque model of Parkinson’s disease.
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  Neuroscience Letters. 2014-04-01. 566 : 72-76.
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• Combined fenobam and amantadine treatment promotes robust antidyskinetic effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson’s disease.
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  Mov Disord.. 2014-03-07. 29(6) : 772-779.
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• D1 receptor agonist improves sleep-wake parameters in experimental parkinsonism.
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  Neurobiology of Disease. 2014-03-01. 63 : 20-24.
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• Intra-axonal protein aggregation in the peripheral nervous system.
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  J Peripher Nerv Syst. 2014-03-01. 19(1) : 44-49.
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• Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.
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  Ann Neurol.. 2014-02-18. 75(3) : 351-362.
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• Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson’s disease and l-DOPA-induced dyskinesia.
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• Immediate-early gene expression in structures outside the basal ganglia is associated to l-DOPA-induced dyskinesia.
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• L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum.
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• Depressive-like behavioral profiles in captive-bred single- and socially-housed rhesus and cynomolgus macaques: a species comparison.
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• Neurological drug development: a guide for a start-up biotech.
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• Premotor parkinsonism models.
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• Premotor parkinsonism models.
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• Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia.
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• Single-molecule imaging of the functional crosstalk between surface NMDA and dopamine D1 receptors.
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  Proceedings of the National Academy of Sciences. 2013-10-14. 110(44) : 18005-18010.
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• Viral vectors in primate research: Examples from Parkinson’s disease research
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• D1 dopamine receptor-mediated LTP at GABA synapses encodes motivation to self-administer cocaine in rats.
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• Birth origin differentially affects depressive-like behaviours: are captive-born cynomolgus monkeys more vulnerable to depression than their wild-born counterparts?
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• Levodopa gains psychostimulant-like properties after nigral dopaminergic loss.
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• Levodopa-induced dyskinesias in the absence of nigrostriatal degeneration.
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• Behavioural profiles in captive-bred cynomolgus macaques: towards monkey models of mental disorders?
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• Lysosomal impairment in Parkinson’s disease.
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• Effects of memantine and galantamine on cognitive performance in aged rhesus macaques.
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  Neurobiology of Aging. 2013-04-01. 34(4) : 1126-1132.
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• Simvastatin decreases levodopa-induced dyskinesia in monkeys, but not in a randomized, placebo-controlled, multiple cross-over (“n-of-1”) exploratory trial of simvastatin against levodopa-induced dyskinesia in Parkinson’s disease patients.
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  Parkinsonism & Related Disorders. 2013-04-01. 19(4) : 416-421.
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• Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia.
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• Reinforcing properties of Pramipexole in normal and parkinsonian rats.
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• Levodopa improves motor deficits but can further disrupt cognition in a macaque Parkinson model.
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• Age-dependent α-synuclein aggregation in the Microcebus murinus lemur primate.
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• Nociceptin/orphanin FQ receptor agonists attenuate L-DOPA-induced dyskinesias.
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• Nociceptin/orphanin FQ receptor agonists attenuate L-DOPA-induced dyskinesias.
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• Experimental reappraisal of continuous dopaminergic stimulation against L-dopa-induced dyskinesia.
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• Coordinated reset has sustained aftereffects in Parkinsonian monkeys.
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• Altered pallido-pallidal synaptic transmission leads to aberrant firing of globus pallidus neurons in a rat model of Parkinson’s disease.
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• Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove.
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• A critique of available scales and presentation of the Non-Human Primate Dyskinesia Rating Scale.
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• Animal models of Parkinson’s disease: limits and relevance to neuroprotection studies.
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• Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.
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• Localization of endogenous morphine-like compounds in the mouse spinal cord.
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• Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques.
  Benjamin Dehay, Deniz Dalkara, Sandra Dovero, Qin Li, Erwan Bezard.
  Sci Rep. 2012-02-09. 2(1)
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• Toward an animal model of restless legs syndrome?
  Imad Ghorayeb, Erwan Bezard.
  Mov. Disord.. 2012-01-30. 27(3) : 337-338.
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• Functional connectivity in human and monkey brain: new insights for understanding movement disorders?
  Palma Pró-Sistiaga, Erwan Bézard.
  Mov. Disord.. 2012-01-01. 27(1) : 61-61.
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• Modeling Parkinson’s disease in primates: The MPTP model.
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  Cold Spring Harbor Perspectives in Medicine. 2011-12-22. 2(3) : a009308-a009308.
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• Contribution of pre-synaptic mechanisms to L-DOPA-induced dyskinesia.
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  Neuroscience. 2011-12-01. 198 : 245-251.
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• What should be said to the lay public regarding ADHD etiology.
  Francois Gonon, Erwan Bezard, Thomas Boraud.
  Am. J. Med. Genet.. 2011-08-31. 156(8) : 989-991.
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• Endogenous morphine-like compound immunoreactivity increases in parkinsonism.
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  Brain. 2011-07-08. 134(8) : 2321-2338.
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• A new cerebral hemorrhage model in cynomolgus macaques created by injection of autologous anticoagulated blood into the brain.
  Hua Zhu, Qin Li, Ming Feng, Yun-Xin Chen, Hao Li, Jin-Jiang Sun, Chun-Hua Zhao, Ren-Zhi Wang, Erwan Bezard, Chuan Qin.
  Journal of Clinical Neuroscience. 2011-07-01. 18(7) : 955-960.
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• A tale on animal models of Parkinson’s disease.
  Erwan Bezard, Serge Przedborski.
  Mov. Disord.. 2011-05-01. 26(6) : 993-1002.
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• Priorities in Parkinson’s disease research.
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  Nat Rev Drug Discov. 2011-05-01. 10(5) : 377-393.
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• New animal models of Parkinson’s disease.
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  Mov. Disord.. 2011-04-05. 26(7) : 1198-1205.
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• New animal models of Parkinson’s disease.
  Benjamin Dehay, Erwan Bezard.
  Mov. Disord.. 2011-04-05. 26(7) : 1198-1205.
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• Misrepresentation of neuroscience data might give rise to misleading conclusions in the media: the case of attention deficit hyperactivity disorder.
  Francois Gonon, Erwan Bezard, Thomas Boraud.
  PLoS ONE. 2011-01-31. 6(1) : e14618.
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• Migration and differentiation of human mesenchymal stem cells in the normal rat brain.
  Jia-Mei Li, Hua Zhu, Shan Lu, Ying Liu, Qin Li, Paula Ravenscroft, Yan-Feng Xu, Lan Huang, Chun-Mei Ma, Erwan Bezard, Robert Chun-Hua Zhao, Ren-zhi Wang, Chuan Qin.
  Neurological Research. 2011-01-01. 33(1) : 84-92.
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• Protein aggregation in the aging retina.
  François Leger, Pierre-Olivier Fernagut, Marie-Hélène Canron, Sandy Léoni, Claude Vital, François Tison, Erwan Bezard, Anne Vital.
  J Neuropathol Exp Neurol. 2011-01-01. 70(1) : 63-68.
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• Molecular mechanisms of l-DOPA-induced dyskinesia.
  Gilberto Fisone, Erwan Bezard.
  International Review of Neurobiology. 2011-01-01. : 95-122.
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• Double-dissociation of the catecholaminergic modulation of synaptic transmission in the oval bed nucleus of the stria terminalis.
  Michal Krawczyk, François Georges, Robyn Sharma, Xenos Mason, Amandine Berthet, Erwan Bézard, Éric C. Dumont.
  Journal of Neurophysiology. 2011-01-01. 105(1) : 145-153.
  10.1152/jn.00710.2010
• Metabolic activity of the subthalamic nucleus in a primate model of L-dopa-unresponsive parkinsonism.
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  Neurological Research. 2010-12-01. 32(10) : 1050-1053.
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• Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia.
  S. Fasano, E. Bezard, A. D'Antoni, V. Francardo, M. Indrigo, L. Qin, S. Dovero, M. Cerovic, M. A. Cenci, R. Brambilla.
  Proceedings of the National Academy of Sciences. 2010-11-29. 107(50) : 21824-21829.
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• Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys.
  Pierre-Olivier Fernagut, Qin Li, Sandra Dovero, Piu Chan, Tao Wu, Paula Ravenscroft, Michael Hill, Zhenwen Chen, Erwan Bezard.
  PLoS ONE. 2010-11-22. 5(11) : e14053.
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• Neuroanatomical study of the A11 diencephalospinal pathway in the non-human primate.
  Quentin Barraud, Ibrahim Obeid, Incarnation Aubert, Gregory Barrière, Hugues Contamin, Steve McGuire, Paula Ravenscroft, Gregory Porras, François Tison, Erwan Bezard, Imad Ghorayeb.
  PLoS ONE. 2010-10-13. 5(10) : e13306.
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• Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia.
  Daniella Rylander, Martin Parent, Sean S. O'Sullivan, Sandra Dovero, Andrew J. Lees, Erwan Bezard, Laurent Descarries, M. Angela Cenci.
  Ann Neurol.. 2010-09-29. 68(5) : 619-628.
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• A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys.
  Daniella Rylander, Hanna Iderberg, Qin Li, Andrzej Dekundy, Jinlan Zhang, Hao Li, Ren Baishen, Wojciech Danysz, Erwan Bezard, M. Angela Cenci.
  Neurobiology of Disease. 2010-09-01. 39(3) : 352-361.
  10.1016/j.nbd.2010.05.001
• Distinct changes in cAMP and extracellular signal-regulated protein kinase signalling in L-DOPA-induced dyskinesia.
  Emanuela Santini, Veronique Sgambato-Faure, Qin Li, Marc Savasta, Sandra Dovero, Gilberto Fisone, Erwan Bezard.
  PLoS ONE. 2010-08-23. 5(8) : e12322.
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• Genes regulated in MPTP-treated macaques and human Parkinson’s disease suggest a common signature in prefrontal cortex.
  Markus Storvik, Marie-Jeanne Arguel, Sandra Schmieder, Audrey Delerue-Audegond, Qin Li, Chuan Qin, Anne Vital, Bernard Bioulac, Christian E. Gross, Garry Wong, Jean-Louis Nahon, Erwan Bezard.
  Neurobiology of Disease. 2010-06-01. 38(3) : 386-394.
  10.1016/j.nbd.2010.02.008
• Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinson’s disease.
  M. R. Ahmed, A. Berthet, E. Bychkov, G. Porras, Q. Li, B. H. Bioulac, Y. T. Carl, B. Bloch, S. Kook, I. Aubert, S. Dovero, E. Doudnikoff, V. V. Gurevich, E. V. Gurevich, E. Bezard.
  Science Translational Medicine. 2010-04-21. 2(28) : 28ra28-28ra28.
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• Synaptic recruitment of AMPA glutamate receptor subunits in levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate.
  Monty A. Silverdale, Christopher Kobylecki, Penelope J. Hallett, Qin Li, Anthone W. Dunah, Paula Ravenscroft, Erwan Bezard, Jonathan M. Brotchie.
  Synapse. 2010-02-01. 64(2) : 177-180.
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• Treating Parkinson’s disease: preserve the spines! (Commentary on Soderstrom et al.).
  Erwan Bezard.
  European Journal of Neuroscience. 2010-02-01. 31(3) : 477-477.
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• Basal Ganglia circuits underlying the pathophysiology of levodopa-induced dyskinesia.
  Pedro Barroso-Chinea.
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• IGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP.
  Agnès Nadjar, Olivier Berton, Shuhong Guo, Patricia Leneuve, Sandra Dovero, Elsa Diguet, François Tison, Baolu Zhao, Martin Holzenberger, Erwan Bezard.
  Neurobiology of Aging. 2009-12-01. 30(12) : 2021-2030.
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• Initial clinical manifestations of Parkinson’s disease: features and pathophysiological mechanisms.
  Maria C Rodriguez-Oroz, Marjan Jahanshahi, Paul Krack, Irene Litvan, Raúl Macias, Erwan Bezard, José A Obeso.
  The Lancet Neurology. 2009-12-01. 8(12) : 1128-1139.
  10.1016/s1474-4422(09)70293-5
• Involvement of canonical and non-canonical D1 dopamine receptor signalling pathways in L-dopa-induced dyskinesia.
  Céline Guigoni, Erwan Bezard.
  Parkinsonism & Related Disorders. 2009-12-01. 15 : S64-S67.
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• Chronic dopaminergic stimulation in Parkinson’s disease: from dyskinesias to impulse control disorders.
  Valerie Voon, Pierre-Olivier Fernagut, Jeff Wickens, Christelle Baunez, Manuel Rodriguez, Nancy Pavon, Jorge L Juncos, José A Obeso, Erwan Bezard.
  The Lancet Neurology. 2009-12-01. 8(12) : 1140-1149.
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• Dopamine receptors and L-dopa-induced dyskinesia.
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  Parkinsonism & Related Disorders. 2009-12-01. 15 : S8-S12.
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• Chronic dopaminergic stimulation in Parkinson’s disease: from dyskinesias to impulse control disorders.
  Valerie Voon, Pierre-Olivier Fernagut, Jeff Wickens, Christelle Baunez, Manuel Rodriguez, Nancy Pavon, Jorge L Juncos, José A Obeso, Erwan Bezard.
  The Lancet Neurology. 2009-12-01. 8(12) : 1140-1149.
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• Dopamine receptors and L-dopa-induced dyskinesia.
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  Parkinsonism & Related Disorders. 2009-12-01. 15 : S8-S12.
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• Initial clinical manifestations of Parkinson’s disease: features and pathophysiological mechanisms.
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  The Lancet Neurology. 2009-12-01. 8(12) : 1128-1139.
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• Involvement of canonical and non-canonical D1 dopamine receptor signalling pathways in L-dopa-induced dyskinesia.
  Céline Guigoni, Erwan Bezard.
  Parkinsonism & Related Disorders. 2009-12-01. 15 : S64-S67.
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• Sleep disorders in Parkinson’s disease: the contribution of the MPTP non-human primate model.
  Quentin Barraud, Virginie Lambrecq, Claude Forni, Steve McGuire, Michael Hill, Bernard Bioulac, Emmanuel Balzamo, Erwan Bezard, François Tison, Imad Ghorayeb.
  Experimental Neurology. 2009-10-01. 219(2) : 574-582.
  10.1016/j.expneurol.2009.07.019
• High frequency stimulation of the entopeduncular nucleus sets the cortico-basal ganglia network to a new functional state in the dystonic hamster.
  René Reese, Giselle Charron, Agnès Nadjar, Incarnation Aubert, Marie-Laure Thiolat, Melanie Hamann, Angelika Richter, Erwan Bezard, Wassilios G Meissner.
  Neurobiology of Disease. 2009-09-01. 35(3) : 399-405.
  10.1016/j.nbd.2009.05.022
• Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease.
  Olivier Berton, Céline Guigoni, Qin Li, Bernard H. Bioulac, Incarnation Aubert, Christian E. Gross, Ralph J. DiLeone, Eric J. Nestler, Erwan Bezard.
  Biological Psychiatry. 2009-09-01. 66(6) : 554-561.
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• The nigrostriatal pathway in Creutzfeldt-Jakob disease.
  Anne Vital, Pierre-Olivier Fernagut, Marie-Hélène Canron, Julien Joux, Erwan Bezard, Marie-Laure Martin-Negrier, Claude Vital, François Tison.
  J Neuropathol Exp Neurol. 2009-07-01. 68(7) : 809-815.
  10.1097/nen.0b013e3181abdae8
• Pharmacological analysis demonstrates dramatic alteration of D1 dopamine receptor neuronal distribution in the rat analog of L-DOPA-induced dyskinesia.
  A. Berthet, G. Porras, E. Doudnikoff, H. Stark, M. Cador, E. Bezard, B. Bloch.
  Journal of Neuroscience. 2009-04-15. 29(15) : 4829-4835.
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• The pathologic features of neurocutaneous melanosis in a cynomolgus macaque.
  Y. Chen, W. Deng, H. Zhu, J. Li, Y. Xu, X. Dai, C. Jia, Q. Kong, L. Huang, Y. Liu, C. Ma, C. Xiao, Q. Li, E. Bezard, C. Qin.
  Vet Pathol. 2009-03-09. 46(4) : 773-775.
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• Antagonizing L-type Ca2+ channel reduces development of abnormal involuntary movement in the rat model of L-3,4-dihydroxyphenylalanine-induced dyskinesia.
  Stefan Schuster, Evelyne Doudnikoff, Daniella Rylander, Amandine Berthet, Incarnation Aubert, Carina Ittrich, Bertrand Bloch, M. Angela Cenci, D. James Surmeier, Bastian Hengerer, Erwan Bezard.
  Biological Psychiatry. 2009-03-01. 65(6) : 518-526.
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• Neurochemical plasticity in the enteric nervous system of a primate animal model of experimental Parkinsonism.
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  Neurogastroenterology & Motility. 2009-02-01. 21(2) : 215-222.
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• Priming for l-dopa-induced dyskinesia in Parkinson’s disease: a feature inherent to the treatment or the disease?
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  Progress in Neurobiology. 2009-01-01. 87(1) : 1-9.
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• The vascular endothelial cell is a new origin of melanin pigment on cynomolgus macaque with neurocutaneous melanosis.
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  Pigment Cell & Melanoma Research. 2008-12-01. 21(6) : 710-711.
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• Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia.
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• Striatal histone modifications in models of levodopa-induced dyskinesia.
  Anthony P. Nicholas, Farah D. Lubin, Penelope J. Hallett, Padmapriya Vattem, Paula Ravenscroft, Erwan Bezard, Shaobo Zhou, Susan H. Fox, Jonathan M. Brotchie, J. David Sweatt, David G. Standaert.
  J Neurochem. 2008-07-01. 106(1) : 486-494.
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• Differential behavioral effects of partial bilateral lesions of ventral tegmental area or substantia nigra pars compacta in rats.
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  Neuroscience. 2008-06-01. 153(4) : 1213-1224.
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• Intratelencephalic corticostriatal neurons equally excite striatonigral and striatopallidal neurons and their discharge activity is selectively reduced in experimental parkinsonism.
  Bérangère Ballion, Nicolas Mallet, Erwan Bézard, José Luis Lanciego, Francois Gonon.
  European Journal of Neuroscience. 2008-04-25. 27(9) : 2313-2321.
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• The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson’s disease.
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• Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure.
  Birger Scholz, Marcus Svensson, Henrik Alm, Karl Sköld, Maria Fälth, Kim Kultima, Céline Guigoni, Evelyne Doudnikoff, Qin Li, Alan R. Crossman, Erwan Bezard, Per E. Andrén.
  PLoS ONE. 2008-02-13. 3(2) : e1589.
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• Neuroprotective effects of rotigotine in the acute MPTP-lesioned mouse model of Parkinson’s disease.
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  Neuroscience Letters. 2008-02-01. 432(1) : 30-34.
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• Preclinical development of gene therapy for Parkinson’s disease.
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  Experimental Neurology. 2008-01-01. 209(1) : 72-81.
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• RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson’s disease.
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  Journal of Neuroscience. 2007-12-26. 27(52) : 14338-14348.
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• Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson’s disease through inhibition of ROS-NO pathway.
  Shuhong Guo, Jingqi Yan, Tangbin Yang, Xianqiang Yang, Erwan Bezard, Baolu Zhao.
  Biological Psychiatry. 2007-12-01. 62(12) : 1353-1362.
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• Noradrenergic modulation of subthalamic nucleus activity: behavioral and electrophysiological evidence in intact and 6-hydroxydopamine-lesioned rats.
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  Journal of Neuroscience. 2007-09-05. 27(36) : 9595-9606.
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• Altered D(1) dopamine receptor trafficking in parkinsonian and dyskinetic non-human primates.
  Céline Guigoni, Evelyne Doudnikoff, Qin Li, Bertrand Bloch, Erwan Bezard.
  Neurobiology of Disease. 2007-05-01. 26(2) : 452-463.
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• Impact of chronic subthalamic high-frequency stimulation on metabolic basal ganglia activity: a 2-deoxyglucose uptake and cytochrome oxidase mRNA study in a macaque model of Parkinson’s disease.
  Wassilios Meissner, Celine Guigoni, Laetitia Cirilli, Maurice Garret, Bernard H. Bioulac, Christian E. Gross, Erwan Bezard, Abdelhamid Benazzouz.
  European Journal of Neuroscience. 2007-04-05. 25(5) : 1492-1500.
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• Enhanced preproenkephalin-B-derived opioid transmission in striatum and subthalamic nucleus converges upon globus pallidus internalis in L-3,4-dihydroxyphenylalanine-induced dyskinesia.
  Incarnation Aubert, Céline Guigoni, Qin Li, Sandra Dovero, Bernard H. Bioulac, Christian E. Gross, Alan R. Crossman, Bertrand Bloch, Erwan Bezard.
  Biological Psychiatry. 2007-04-01. 61(7) : 836-844.
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• Rotigotine treatment partially protects from MPTP toxicity in a progressive macaque model of Parkinson’s disease.
  Dieter Scheller, Piu Chan, Qin Li, Tao Wu, Renling Zhang, Le Guan, Paula Ravenscroft, Celine Guigoni, Alan R. Crossman, Michael Hill, Erwan Bezard.
  Experimental Neurology. 2007-02-01. 203(2) : 415-422.
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• Shaping of motor responses by incentive values through the basal ganglia.
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  Journal of Neuroscience. 2007-01-31. 27(5) : 1176-1183.
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• Novel pharmacological targets for the treatment of Parkinson’s disease.
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  Nat Rev Drug Discov. 2006-10-01. 5(10) : 845-854.
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• A call for clinically driven experimental design in assessing neuroprotection in experimental Parkinsonism.
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  Behavioural Pharmacology. 2006-09-01. 17(5-6) : 379-382.
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• Traditional Chinese medicine for Parkinson’s disease: a review of Chinese literature.
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• Phenotype of striatofugal medium spiny neurons in parkinsonian and dyskinetic nonhuman primates: a call for a reappraisal of the functional organization of the basal ganglia.
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• Temporal and spatial alterations in GPi neuronal encoding might contribute to slow down movement in Parkinsonian monkeys.
  Arthur Leblois, Wassilios Meissner, Erwan Bezard, Bernard Bioulac, Christian E. Gross, Thomas Boraud.
  European Journal of Neuroscience. 2006-08-01. 24(4) : 1201-1208.
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• 5-HT1A receptor agonist-mediated protection from MPTP toxicity in mouse and macaque models of Parkinson’s disease.
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  Neurobiology of Disease. 2006-07-01. 23(1) : 77-86.
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• Increased slow oscillatory activity in substantia nigra pars reticulata triggers abnormal involuntary movements in the 6-OHDA-lesioned rat in the presence of excessive extracellular striatal dopamine.
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  Neurobiology of Disease. 2006-06-01. 22(3) : 586-598.
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• Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice.
  Ainhoa Bilbao, Andrea Cippitelli, Ana Belén Martín, Noelia Granado, Oscar Ortiz, Erwan Bezard, Jiang-Fan Chen, Miguel Navarro, Fernando Rodríguez de Fonseca, R Moratalla.
  Psychopharmacology. 2006-02-10. 185(2) : 160-168.
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• The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders.
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  10.2174/187152706784111551
• The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders.
  L. Leriche, E. Bezard, C. Gross, O. Guillin, B. Foll, J. Diaz, P. Sokoloff.
  CNSNDDT. 2006-02-01. 5(1) : 25-43.
  10.2174/187152706784111551
• Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: a proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson’s disease using DIGE.
  Kim Kultima, Birger Scholz, Henrik Alm, Karl Skold, Marcus Svensson, Alan R Crossman, Erwan Bezard, Per E Andren, Ingrid Lonnstedt.
  BMC Bioinformatics. 2006-01-01. 7(1) : 475.
  10.1186/1471-2105-7-475
• Unraveling substantia nigra sequential gene expression in a progressive MPTP-lesioned macaque model of Parkinson’s disease.
  F BASSILANA, N MACE, Q LI, J STUTZMANN, C GROSS, L PRADIER, J BENAVIDES, J MENAGER, E BEZARD.
  Neurobiology of Disease. 2005-10-01. 20(1) : 93-103.
  10.1016/j.nbd.2005.02.005
• Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway.
  Shuhong Guo, Erwan Bezard, Baolu Zhao.
  Free Radical Biology and Medicine. 2005-09-01. 39(5) : 682-695.
  10.1016/j.freeradbiomed.2005.04.022
• Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway.
  Shuhong Guo, Erwan Bezard, Baolu Zhao.
  Free Radical Biology and Medicine. 2005-09-01. 39(5) : 682-695.
  10.1016/j.freeradbiomed.2005.04.022
• Levodopa-induced dyskinesia in MPTP-treated macaques is not dependent on the extent and pattern of nigrostrial lesioning.
  Céline Guigoni, Sandra Dovero, Incarnation Aubert, Qin Li, Bernard H. Bioulac, Bertrand Bloch, Eugenia V. Gurevich, Christian E. Gross, Erwan Bezard.
  European Journal of Neuroscience. 2005-07-01. 22(1) : 283-287.
  10.1111/j.1460-9568.2005.04196.x
• Investigating the receptor-independent neuroprotective mechanisms of nicotine in mitochondria.
  Yu-Xiang Xie, Erwan Bezard, Bao-Lu Zhao.
  J. Biol. Chem.. 2005-06-27. 280(37) : 32405-32412.
  10.1074/jbc.m504664200
• Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors.
  C. Guigoni, I. Aubert, Q. Li, V.V. Gurevich, J.L. Benovic, S. Ferry, U. Mach, H. Stark, L. Leriche, K. Håkansson, Bernard H. Bioulac, Christian E. Gross, Pierre Sokoloff, Gilberto Fisone, E.V. Gurevich, Bertrand Bloch, Erwan Bezard.
  Parkinsonism & Related Disorders. 2005-06-01. 11 : S25-S29.
  10.1016/j.parkreldis.2004.11.005
• Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson’s disease.
  P.J. Hallett, A.W. Dunah, P. Ravenscroft, S. Zhou, E. Bezard, A.R. Crossman, J.M. Brotchie, D.G. Standaert.
  Neuropharmacology. 2005-03-01. 48(4) : 503-516.
  10.1016/j.neuropharm.2004.11.008
• L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain.
  E. Bezard, C.E. Gross, Li Qin, V.V. Gurevich, J.L. Benovic, E.V. Gurevich.
  Neurobiology of Disease. 2005-03-01. 18(2) : 323-335.
  10.1016/j.nbd.2004.10.005
• Partial bilateral mesencephalic lesions affect D1 but not D2 binding in both the striatum and cortex.
  Elsa Pioli, Reinhard Sohr, Wassilios Meissner, Nicole Barthe, Christian E. Gross, Erwan Bezard, Bernard H. Bioulac.
  Neurochemistry International. 2004-12-01. 45(7) : 995-1004.
  10.1016/j.neuint.2004.06.003
• Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia.
  Incarnation Aubert, Céline Guigoni, Kerstin Håkansson, Qin Li, Sandra Dovero, Nicole Barthe, Bernard H. Bioulac, Christian E. Gross, Gilberto Fisone, Bertrand Bloch, Erwan Bezard.
  Ann Neurol.. 2004-10-27. 57(1) : 17-26.
  10.1002/ana.20296
• Asymmetrically lesioned mesencephalon in healthy rodents: call for caution.
  Elsa Y. Pioli, Sandra Dovero, Bernard H. Bioulac, Christian E. Gross, Erwan Bezard.
  Brain Research. 2004-10-01. 1022(1-2) : 251-253.
  10.1016/j.brainres.2004.07.014
• Rise and fall of minocycline in neuroprotection: need to promote publication of negative results.
  Elsa Diguet, Christian E. Gross, François Tison, Erwan Bezard.
  Experimental Neurology. 2004-09-01. 189(1) : 1-4.
  10.1016/j.expneurol.2004.05.016
• Deleterious effects of minocycline in animal models of Parkinson’s disease and Huntington’s disease.
  Elsa Diguet, Pierre-Olivier Fernagut, Xing Wei, Yansheng Du, Richard Rouland, Christian Gross, Erwan Bezard, François Tison.
  European Journal of Neuroscience. 2004-06-01. 19(12) : 3266-3276.
  10.1111/j.0953-816x.2004.03372.x
• Neuroprotective strategies for Parkinson’s disease: conceptual limits of animal models and clinical trials.
  Wassilios Meissner, Michael P. Hill, François Tison, Christian E. Gross, Erwan Bezard.
  Trends in Pharmacological Sciences. 2004-05-01. 25(5) : 249-253.
  10.1016/j.tips.2004.03.003
• Levetiracetam potentiates the antidyskinetic action of amantadine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson’s disease.
  M. P. Hill.
  Journal of Pharmacology and Experimental Therapeutics. 2004-04-02. 310(1) : 386-394.
  10.1124/jpet.104.066191
• High-frequency stimulation of both zona incerta and subthalamic nucleus induces a similar normalization of basal ganglia metabolic activity in experimental parkinsonism.
  ABDELHAMID BENAZZOUZ, CHUN HWEI TAI, WASSILIOS MEISSNER, BERNARD BIOULAC, ERWAN BEZARD, CHRISTIAN GROSS.
  The FASEB Journal. 2004-03-01. 18(3) : 528-530.
  10.1096/fj.03-0576fje
• High frequency stimulation of the entopeduncular nucleus has no effect on striatal dopaminergic transmission.
  Wassilios Meissner, Daniel Harnack, Nora Hoessle, Erwan Bezard, Christine Winter, Rudolf Morgenstern, Andreas Kupsch.
  Neurochemistry International. 2004-03-01. 44(4) : 281-286.
  10.1016/s0197-0186(03)00138-4
• Levetiracetam improves choreic levodopa-induced dyskinesia in the MPTP-treated macaque.
  Erwan Bezard, Michael P. Hill, Alan R. Crossman, Jonathan M. Brotchie, Anne Michel, Renee Grimée, Henrik Klitgaard.
  European Journal of Pharmacology. 2004-02-01. 485(1-3) : 159-164.
  10.1016/j.ejphar.2003.11.065
• Levetiracetam improves choreic levodopa-induced dyskinesia in the MPTP-treated macaque.
  Erwan Bezard, Michael P. Hill, Alan R. Crossman, Jonathan M. Brotchie, Anne Michel, Renee Grimée, Henrik Klitgaard.
  European Journal of Pharmacology. 2004-02-01. 485(1-3) : 159-164.
  10.1016/j.ejphar.2003.11.065
• Neuroprotective agents for clinical trials in Parkinson’s disease: a systematic assessment.
  E. Diguet, C. E. Gross, E. Bezard, F. Tison, N. Stefanova, G. K. Wenning, B. Ravina, S. Fagan, R. Hart, C. Hovinga, D. Murphy, T. Dawson, J. Marler.
  Neurology. 2004-01-12. 62(1) : 158-159.
  10.1212/wnl.62.1.158
• Neuroprotective agents for clinical trials in Parkinson’s disease: a systematic assessment.
  E. Diguet, C. E. Gross, E. Bezard, F. Tison, N. Stefanova, G. K. Wenning, B. Ravina, S. Fagan, R. Hart, C. Hovinga, D. Murphy, T. Dawson, J. Marler.
  Neurology. 2004-01-12. 62(1) : 158-159.
  10.1212/wnl.62.1.158
• Brain-derived neurotrophic factor and the plasticity of the mesolimbic dopamine pathway.
  Oliver Guillin, Nathalie Griffon, Jorge Diaz, Bernard Le Foll, Erwan Bezard, Christian Gross, Chris Lammers, Holger Stark, Patrick Carroll, Jean-Charles Schwartz.
  International Review of Neurobiology. 2004-01-01. : 425-444.
  10.1016/s0074-7742(04)59016-5
• Levetiracetam Interferes With the L-dopa priming process in MPTP-lesioned drug-naive marmosets.
  Michael P Hill, Jonathan M Brotchie, Alan R Crossman, Erwan Bezard, Anne Michel, Renee Grim??e, Henrik Klitgaard.
  Clinical Neuropharmacology. 2004-01-01. 27(4) : 171-177.
  10.1097/01.wnf.0000135478.70905.3d
• Brain-derived neurotrophic factor and the plasticity of the mesolimbic dopamine pathway.
  Oliver Guillin, Nathalie Griffon, Jorge Diaz, Bernard Le Foll, Erwan Bezard, Christian Gross, Chris Lammers, Holger Stark, Patrick Carroll, Jean-Charles Schwartz.
  International Review of Neurobiology. 2004-01-01. : 425-444.
  10.1016/s0074-7742(04)59016-5
• Levetiracetam Interferes With the L-dopa priming process in MPTP-lesioned drug-naive marmosets.
  Michael P Hill, Jonathan M Brotchie, Alan R Crossman, Erwan Bezard, Anne Michel, Renee Grim??e, Henrik Klitgaard.
  Clinical Neuropharmacology. 2004-01-01. 27(4) : 171-177.
  10.1097/01.wnf.0000135478.70905.3d
• Brain-derived neurotrophic factor controls dopamine D3 receptor expression: therapeutic implications in Parkinson’s disease.
  Olivier Guillin, Nathalie Griffon, Erwan Bezard, Ludovic Leriche, Jorge Diaz, Christian Gross, Pierre Sokoloff.
  European Journal of Pharmacology. 2003-11-01. 480(1-3) : 89-95.
  10.1016/j.ejphar.2003.08.096
• Brain-derived neurotrophic factor controls dopamine D3 receptor expression: therapeutic implications in Parkinson’s disease.
  Olivier Guillin, Nathalie Griffon, Erwan Bezard, Ludovic Leriche, Jorge Diaz, Christian Gross, Pierre Sokoloff.
  European Journal of Pharmacology. 2003-11-01. 480(1-3) : 89-95.
  10.1016/j.ejphar.2003.08.096
• Electrophysiological and metabolic evidence that high-frequency stimulation of the subthalamic nucleus bridles neuronal activity in the subthalamic nucleus and the substantia nigra reticulata.
  CHUN-HWEI TAI, THOMAS BORAUD, ERWAN BEZARD, BERNARD BIOULAC, CHRISTIAN GROSS, ABDELHAMID BENAZZOUZ.
  The FASEB Journal. 2003-10-01. 17(13) : 1820-1830.
  10.1096/fj.03-0163com
• Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by L-dopa and ropinirole in the MPTP-lesioned marmoset.
  Michael P. Hill, Erwan Bezard, Steven G. McGuire, Alan R. Crossman, Jonathan M. Brotchie, Ann Michel, Renee Grimée, Henrik Klitgaard.
  Mov. Disord.. 2003-08-21. 18(11) : 1301-1305.
  10.1002/mds.10542
• Neuroprotection for Parkinson’s disease: a call for clinically driven experimental design.
  Erwan Bezard.
  The Lancet Neurology. 2003-07-01. 2(7) : 393.
  10.1016/s1474-4422(03)00432-0
• Presymptomatic diagnosis of experimental Parkinsonism with 123I-PE2I SPECT.
  Caroline Prunier, Erwan Bézard, Jérôme Montharu, Marina Mantzarides, Jean-Claude Besnard, Jean-Louis Baulieu, Christian Gross, Denis Guilloteau, Sylvie Chalon.
  NeuroImage. 2003-07-01. 19(3) : 810-816.
  10.1016/s1053-8119(03)00163-0
• Neuroprotection for Parkinson’s disease: a call for clinically driven experimental design.
  Erwan Bezard.
  The Lancet Neurology. 2003-07-01. 2(7) : 393.
  10.1016/s1474-4422(03)00432-0
• Presymptomatic diagnosis of experimental Parkinsonism with 123I-PE2I SPECT.
  Caroline Prunier, Erwan Bézard, Jérôme Montharu, Marina Mantzarides, Jean-Claude Besnard, Jean-Louis Baulieu, Christian Gross, Denis Guilloteau, Sylvie Chalon.
  NeuroImage. 2003-07-01. 19(3) : 810-816.
  10.1016/s1053-8119(03)00163-0
• Compensatory regulation of striatal neuropeptide gene expression occurs before changes in metabolic activity of basal ganglia nuclei.
  Wassilios Meissner, Sandra Dovero, Bernard Bioulac, Christian E. Gross, Erwan Bezard.
  Neurobiology of Disease. 2003-06-01. 13(1) : 46-54.
  10.1016/s0969-9961(03)00011-1
• Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function.
  Erwan Bézard, Sandrine Ferry, Ulrich Mach, Holger Stark, Ludovic Leriche, Thomas Boraud, Christian Gross, Pierre Sokoloff.
  Nat Med. 2003-05-12. 9(6) : 762-767.
  10.1038/nm875
• Presymptomatic compensation in Parkinson’s disease is not dopamine-mediated.
  Erwan Bezard, Christian E. Gross, Jonathan M. Brotchie.
  Trends in Neurosciences. 2003-04-01. 26(4) : 215-221.
  10.1016/s0166-2236(03)00038-9
• Presymptomatic compensation in Parkinson’s disease is not dopamine-mediated.
  Erwan Bezard, Christian E. Gross, Jonathan M. Brotchie.
  Trends in Neurosciences. 2003-04-01. 26(4) : 215-221.
  10.1016/s0166-2236(03)00038-9
• Pattern of levodopa-induced striatal changes is different in normal and MPTP-lesioned mice.
  Christian E. Gross, Paula Ravenscroft, Sandra Dovero, Mohamed Jaber, Bernard Bioulac, Erwan Bezard.
  Journal of Neurochemistry. 2003-03-01. 84(6) : 1246-1255.
  10.1046/j.1471-4159.2003.01600.x
• Pattern of levodopa-induced striatal changes is different in normal and MPTP-lesioned mice.
  Christian E. Gross, Paula Ravenscroft, Sandra Dovero, Mohamed Jaber, Bernard Bioulac, Erwan Bezard.
  Journal of Neurochemistry. 2003-03-01. 84(6) : 1246-1255.
  10.1046/j.1471-4159.2003.01600.x
• The deafferented nonhuman primate is not a reliable model of intractable pain.
  Elsa Y. Pioli, Christian E. Gross, Wassilios Meissner, Bernard H. Bioulac, Erwan Bezard.
  Neurological Research. 2003-03-01. 25(2) : 127-129.
  10.1179/016164103101201274
• Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson’s disease.
  Wassilios Meissner, Caroline Prunier, Denis Guilloteau, Sylvie Chalon, Christian E. Gross, Erwan Bezard.
  MN. 2003-01-01. 28(3) : 209-218.
  10.1385/mn:28:3:209
• From single extracellular unit recording in experimental and human Parkinsonism to the development of a functional concept of the role played by the basal ganglia in motor control.
  Thomas Boraud, Erwan Bezard, Bernard Bioulac, Christian E. Gross.
  Progress in Neurobiology. 2002-03-01. 66(4) : 265-283.
  10.1016/s0301-0082(01)00033-8
• From single extracellular unit recording in experimental and human Parkinsonism to the development of a functional concept of the role played by the basal ganglia in motor control.
  Thomas Boraud, Erwan Bezard, Bernard Bioulac, Christian E. Gross.
  Progress in Neurobiology. 2002-03-01. 66(4) : 265-283.
  10.1016/s0301-0082(01)00033-8
• Pathophysiology of levodopa-induced dyskinesia: potential for new therapies.
  Erwan Bezard, Jonathan M. Brotchie, Christian E. Gross.
  Nat Rev Neurosci. 2001-08-01. 2(8) : 577-588.
  10.1038/35086062
• Upregulation of striatal preproenkephalin gene expression occurs before the appearance of parkinsonian signs in 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine monkeys.
  Erwan Bezard, Paula Ravenscroft, Christian E. Gross, Alan R. Crossman, Jonathan M. Brotchie.
  Neurobiology of Disease. 2001-04-01. 8(2) : 343-350.
  10.1006/nbdi.2000.0375
• Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkey.
  Thomas Boraud, Erwan Bezard, Bernard Bioulac, Christian E. Gross.
  Brain. 2001-03-01. 124(3) : 546-557.
  10.1093/brain/124.3.546
• Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkey.
  Thomas Boraud, Erwan Bezard, Bernard Bioulac, Christian E. Gross.
  Brain. 2001-03-01. 124(3) : 546-557.
  10.1093/brain/124.3.546
• Pallidal border cells: an anatomical and electrophysiological study in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey.
  E Bezard, T Boraud, S Chalon, J.M Brotchie, D Guilloteau, C.E Gross.
  Neuroscience. 2001-02-01. 103(1) : 117-123.
  10.1016/s0306-4522(00)00546-7
• Spontaneous long-term compensatory dopaminergic sprouting in MPTP-treated mice.
  Erwan Bezard, Sra Dovero, Christelle Imbert, Thomas Boraud, Christian E. Gross.
  Synapse. 2000-12-01. 38(3) : 363-368.
  10.1002/1098-2396(20001201)38:3<363::aid-syn16>3.3.co;2-1
• Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse.
  Erwan Bezard, Mohamed Jaber, François Gonon, Alain Boireau, Bertrand Bloch, Christian E. Gross.
  European Journal of Neuroscience. 2000-08-01. 12(8) : 2892-2900.
  10.1046/j.1460-9568.2000.00180.x
• Toward a primate model of L-dopa-unresponsive parkinsonism mimicking striatonigral degeneration.
  Imad Ghorayeb, Pierre O. Fernagut, Incarnation Aubert, Erwan Bezard, Werner Poewe, Gregor K. Wenning, François Tison.
  Mov. Disord.. 2000-05-01. 15(3) : 531-536.
  10.1002/1531-8257(200005)15:3<531::aid-mds1017>3.0.co;2-c
• Comparison of eight clinical rating scales used for the assessment of MPTP-induced parkinsonism in the Macaque monkey.
  Christelle Imbert, Erwan Bezard, Stéphane Guitraud, Thomas Boraud, Christian E Gross.
  Journal of Neuroscience Methods. 2000-03-01. 96(1) : 71-76.
  10.1016/s0165-0270(99)00184-3
• Effects of riluzole on the electrophysiological activity of pallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey.
  Th Boraud, E Bezard, J.M Stutzmann, B Bioulac, C.E Gross.
  Neuroscience Letters. 2000-03-01. 281(2-3) : 75-78.
  10.1016/s0304-3940(00)00780-1
• Comparison of eight clinical rating scales used for the assessment of MPTP-induced parkinsonism in the Macaque monkey.
  Christelle Imbert, Erwan Bezard, Stéphane Guitraud, Thomas Boraud, Christian E Gross.
  Journal of Neuroscience Methods. 2000-03-01. 96(1) : 71-76.
  10.1016/s0165-0270(99)00184-3
• Effects of riluzole on the electrophysiological activity of pallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey.
  Th Boraud, E Bezard, J.M Stutzmann, B Bioulac, C.E Gross.
  Neuroscience Letters. 2000-03-01. 281(2-3) : 75-78.
  10.1016/s0304-3940(00)00780-1
• From experimentation to the surgical treatment of Parkinson’s disease: prelude or suite in basal ganglia research?
  C Gross.
  Progress in Neurobiology. 1999-12-01. 59(5) : 509-532.
  10.1016/s0301-0082(99)00015-5
• From experimentation to the surgical treatment of Parkinson’s disease: prelude or suite in basal ganglia research?
  C Gross.
  Progress in Neurobiology. 1999-12-01. 59(5) : 509-532.
  10.1016/s0301-0082(99)00015-5
• Effect of the alpha 2 adrenoreceptor antagonist, idazoxan, on motor disabilities in MPTP-treated monkey.
  Erwan Bezard, Christine Brefel, Francois Tison, Helene Peyro-SaintPaul, Philippe Ladure, Olivier Rascol, Christian E. Gross.
  Progress in Neuro-Psychopharmacology and Biological Psychiatry. 1999-10-01. 23(7) : 1237-1246.
  10.1016/s0278-5846(99)00067-6
• Effect of the alpha 2 adrenoreceptor antagonist, idazoxan, on motor disabilities in MPTP-treated monkey.
  Erwan Bezard, Christine Brefel, Francois Tison, Helene Peyro-SaintPaul, Philippe Ladure, Olivier Rascol, Christian E. Gross.
  Progress in Neuro-Psychopharmacology and Biological Psychiatry. 1999-10-01. 23(7) : 1237-1246.
  10.1016/s0278-5846(99)00067-6
• Trichloroethylene and parkinsonism: a human and experimental observation.
  Dominique Guehl, Erwan Bezard, Sandra Dovero, Thomas Boraud, Bernard Bioulac, Christian Gross.
  Eur J Neurol. 1999-09-01. 6(5) : 609-611.
  10.1046/j.1468-1331.1999.650609.x
• Cortical stimulation and epileptic seizure: a study of the potential risk in primates.
  Erwan Bezard, Thomas Boraud, Jean-Paul Nguyen, Francisco Velasco, Yves Keravel, Christian Gross.
  Neurosurgery. 1999-08-01. 45(2) : 346-350.
  10.1097/00006123-199908000-00030
• Involvement of the subthalamic nucleus in glutamatergic compensatory mechanisms.
  Erwan Bezard, Thomas Boraud, Bernard Bioulac, Christian E. Gross.
  European Journal of Neuroscience. 1999-06-01. 11(6) : 2167-2170.
  10.1046/j.1460-9568.1999.00627.x
• Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.
  Erwan Bezard, Christian E. Gross, Marie-Christine Fournier, Sandra Dovero, Bertrand Bloch, Mohamed Jaber.
  Experimental Neurology. 1999-02-01. 155(2) : 268-273.
  10.1006/exnr.1998.6995
• Riluzole delayed appearance of parkinsonian motor abnormalities in a chronic MPTP monkey model.
  Erwan Bezard, Jean-Marie Stutzmann, Christelle Imbert, Thomas Boraud, Alain Boireau, Christian E. Gross.
  European Journal of Pharmacology. 1998-09-01. 356(2-3) : 101-104.
  10.1016/s0014-2999(98)00537-8
• Compensatory mechanisms in experimental and human parkinsonism: towards a dynamic approach.
  Erwan Bezard, Christian E Gross.
  Progress in Neurobiology. 1998-06-01. 55(2) : 93-116.
  10.1016/s0301-0082(98)00006-9
• Glutamatergic compensatory mechanisms in experimental parkinsonism.
  Erwan Bezard, Bernard Bioulac, Christian E. Gross.
  Progress in Neuro-Psychopharmacology and Biological Psychiatry. 1998-05-01. 22(4) : 609-623.
  10.1016/s0278-5846(98)00030-x
• Effects of L-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey.
  Th Boraud, E Bezard, D Guehl, B Bioulac, Ch Gross.
  Brain Research. 1998-03-01. 787(1) : 157-160.
  10.1016/s0006-8993(97)01563-1
• Experimental models of Parkinson’s disease: from the static to the dynamic.
  Erwan Bezard, Christelle Imbert, Christian E. Gross.
  Reviews in the Neurosciences. 1998-01-01. 9(2)
  10.1515/revneuro.1998.9.2.71
• Effects of different schedules of MPTP administration on dopaminergic neurodegeneration in mice.
  Erwan Bezard, Sandra Dovero, Bernard Bioulac, Christian Gross.
  Experimental Neurology. 1997-11-01. 148(1) : 288-292.
  10.1006/exnr.1997.6648
• Kinetics of nigral degeneration in a chronic model of MPTP-treated mice.
  Erwan Bezard, Sandra Dovero, Bernard Bioulac, Christian E Gross.
  Neuroscience Letters. 1997-09-01. 234(1) : 47-50.
  10.1016/s0304-3940(97)00663-0
• Compensatory effects of glutamatergic inputs to the substantia nigra pars compacta in experimental parkinsonism.
  E Bezard, T Boraud, B Bioulac, C.E Gross.
  Neuroscience. 1997-09-01. 81(2) : 399-404.
  10.1016/s0306-4522(97)00226-1
• Kinetics of nigral degeneration in a chronic model of MPTP-treated mice
  Erwan Bezard, Sandra Dovero, Bernard Bioulac, Christian E Gross.
  Neuroscience Letters. 1997-09-01. 234(1) : 47-50.
  10.1016/S0304-3940(97)00663-0
• Compensatory effects of glutamatergic inputs to the substantia nigra pars compacta in experimental parkinsonism.
  E Bezard, T Boraud, B Bioulac, C.E Gross.
  Neuroscience. 1997-09-01. 81(2) : 399-404.
  10.1016/s0306-4522(97)00226-1
• A chronic MPTP model reproducing the slow evolution of Parkinson’s disease: evolution of motor symptoms in the monkey.
  Erwan Bezard, Christelle Imbert, Xavier Deloire, Bernard Bioulac, Christian E Gross.
  Brain Research. 1997-08-01. 766(1-2) : 107-112.
  10.1016/s0006-8993(97)00531-3
• Subthalamic stimulation elicits hemiballismus in normal monkey.
  Corinne Beurrier, Erwan Bezard, Bernard Bioulac, Christian Gross.
  NeuroReport. 1997-05-01. 8(7) : 1625-1629.
  10.1097/00001756-199705060-00014
• Presymptomatic revelation of experimental parkinsonism.
  Erwan Bezard, Thomas Boraud, Bernard Bioulac, Christian E. Gross.
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