Daniela Felicio

Scientific articles

• Retrotransposition Events Shape the Evolution of the Ataxin-3 Gene Family in Primates
  Daniela Felício, Inês M Martins, Andreia Pinto, Jorge Sequeiros, António Amorim, Alexandra M Lopes, Susana Seixas, Sandra Martins.
  Genome Biology and Evolution. 2026-03-01. 18(3)
  10.1093/gbe/evag047
• Missense variant in TTBK2 kinase domain causes loss of function and impaired protein phosphorylation
  Daniela Felício, Hugo Osório, Conceição Pereira, Ana Filipa Brandão, João Parente Freixo, Inês Carvalho, Ana Paula Sousa, Margarida Castro-Caldas, Jorge Sequeiros, Carolina Lemos, Mariana Santos.
  Scientific Reports. 2025-12-21. 16(1)
  10.1038/s41598-025-32288-0
• Evolutionary history and gene expression of ataxin-3 paralogs
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  Medicine. 2025-01-24. 104(4) : e39478.
  10.1097/MD.0000000000039478
• Evolutionary model of repeat insertions in Ataxin-3 traces the origin of the polyglutamine stretch to an ancestral ubiquitin binding module
  Daniela Felício, Sandra Martins, Guilherme Pimenta Alves, António Amorim, Sandra Macedo‐Ribeiro, Matthew Merski.
  Protein Science. 2024-11-26. 33(12)
  10.1002/pro.5236
• Functional implications of paralog genes in polyglutamine spinocerebellar ataxias
  Daniela Felício, Tanguy Rubat du Mérac, António Amorim, Sandra Martins.
  Hum. Genet.. 2023-10-16. 142(12) : 1651-1676.
  10.1007/s00439-023-02607-4
• Non-coding variants in VAMP2 and SNAP25 affect gene expression: potential implications in migraine susceptibility
  Daniela Felício, Andreia Dias, Sandra Martins, Estefânia Carvalho, Alexandra M. Lopes, Nádia Pinto, Carolina Lemos, Mariana Santos, Miguel Alves-Ferreira.
  J Headache Pain. 2023-06-29. 24(1)
  10.1186/s10194-023-01615-z
• Integrating functional scoring and regulatory data to predict the effect of non-coding SNPs in a complex neurological disease
  Daniela Felício, Miguel Alves-Ferreira, Mariana Santos, Marlene Quintas, Alexandra M Lopes, Carolina Lemos, Nádia Pinto, Sandra Martins.
  Briefings in Functional Genomics. 2023-05-30. 23(2) : 138-149.
  10.1093/bfgp/elad020
• Functional characterization of a novel PRRT2 variant found in a Portuguese patient with hemiplegic migraine
  Andreia Dias, Mariana Santos, Estefânia Carvalho, Daniela Felício, Paulo Silva, Ivânia Alves, Teresa Pinho, Alda Sousa, Miguel Alves‐Ferreira, Carolina Lemos.
  Clinical Genetics. 2023-05-26. 104(4) : 479-485.
  10.1111/cge.14379
• Spinocerebellar ataxia type 11 (SCA11): TTBK2 variants, functions and associated disease mechanisms
  Daniela Felício, Mariana Santos.
  Cerebellum. 2023-03-09. 23(2) : 678-687.
  10.1007/s12311-023-01540-6