Benjamin Dehay
Researcher
Researcher - PhD (DR) / INSERM/ Contact
+33 (0)5 33 51 48 44
www.orcid.org/0000-0003-1723-9045
Scientific articles
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Tau seeds from Alzheimer’s disease brains trigger tau spread in macaques while oligomeric‐Aβ mediates pathology maturation
Morgane Darricau, Changsong Dou, Remi Kinet, Tao Zhu, Li Zhou, Xianglei Li, Aurélie Bedel, Stéphane Claverol, Caroline Tokarski, Taxiarchis Katsinelos, William A. McEwan, Ling Zhang, Ran Gao, Mathieu Bourdenx, Benjamin Dehay, Chuan Qin, Erwan Bezard, Vincent Planche.
Alzheimer's & Dementia. 2023-12-26.
10.1002/alz.13604 -
Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain
Margaux Teil, Sandra Dovero, Mathieu Bourdenx, Marie-Laure Arotcarena, Morgane Darricau, Gregory Porras, Marie-Laure Thiolat, Inés Trigo-Damas, Celine Perier, Cristina Estrada, Nuria Garcia-Carrillo, María Trinidad Herrero, Miquel Vila, José A. Obeso, Erwan Bezard, Benjamin Dehay.
npj Parkinsons Dis.. 2023-09-19. 9(1)
10.1038/s41531-023-00579-w -
Functional and neuropathological changes induced by injection of distinct alpha-synuclein strains: A pilot study in non-human primates
Fayard Audrey, Fenyi Alexis, Lavisse Sonia, Dovero Sandra, Bousset Luc, Tracy Bellande, Lecourtois Sophie, Jouy Christophe, Guillermier Martine, Jan Caroline, Gipchtein Pauline, Dehay Benjamin, Bezard Erwan, Melki Ronald, Hantraye Philippe, Aron Badin Romina.
Neurobiology of Disease. 2023-03-01. : 106086.
10.1016/j.nbd.2023.106086 -
Modulating Lysosomal pH through Innovative Multimerized Succinic Acid-Based Nucleolipid Derivatives
Mathias Brouillard, Rémi Kinet, Marie Joyeux, Benjamin Dehay, Sylvie Crauste-Manciet, Valérie Desvergnes.
Bioconjugate Chem.. 2023-02-28.
10.1021/acs.bioconjchem.3c00041 -
Pathogenic Aspects and Therapeutic Avenues of Autophagy in Parkinson’s Disease
Rémi Kinet, Benjamin Dehay.
Cells. 2023-02-15. 12(4) : 621.
10.3390/cells12040621 -
Tau seeds from patients induce progressive supranuclear palsy pathology and symptoms in primates
Morgane Darricau, Taxiarchis Katsinelos, Flavio Raschella, Tomislav Milekovic, Louis Crochemore, Qin Li, Grégoire Courtine, William A McEwan, Benjamin Dehay, Erwan Bezard, Vincent Planche.
Brain. 2022-11-16.
10.1093/brain/awac428 -
The Zinc Ionophore Clioquinol Reduces Parkinson’s Disease Patient-Derived Brain Extracts-Induced Neurodegeneration
Margaux Teil, Evelyne Doudnikoff, Marie-Laure Thiolat, Sylvain Bohic, Erwan Bezard, Benjamin Dehay.
Mol Neurobiol. 2022-08-02.
10.1007/s12035-022-02974-5 -
Trehalose-Based Nucleolipids as Nanocarriers for Autophagy Modulation: An In Vitro Study
Anthony Cunha, Alexandra Gaubert, Julien Verget, Marie-Laure Thiolat, Philippe Barthélémy, Laurent Latxague, Benjamin Dehay.
Pharmaceutics. 2022-04-13. 14(4) : 857.
10.3390/pharmaceutics14040857 -
Acidic nanoparticles protect against α-synuclein-induced neurodegeneration through the restoration of lysosomal function.
Arotcarena ML, Soria FN, Cunha A, Doudnikoff E, Prévot G, Daniel J, Blanchard-Desce M, Barthélémy P, Bezard E, Crauste-Manciet S, Dehay B..
Aging cell. .
10.1111/acel.13584 -
Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology
Margaux Teil, Sandra Dovero, Mathieu Bourdenx, Marie-Laure Arotcarena, Sandrine Camus, Gregory Porras, Marie-Laure Thiolat, Ines Trigo-Damas, Celine Perier, Cristina Estrada, Nuria Garcia-Carrillo, Michele Morari, Wassilios G Meissner, María Trinidad Herrero, Miquel Vila, Jose A Obeso, Erwan Bezard, Benjamin Dehay.
Brain. 2022-03-14. 145(3) : 1001-1017.
10.1093/brain/awab374 -
Maladie de Parkinson
Erwan Bezard, Benjamin Dehay.
Med Sci (Paris). 2022-01-01. 38(1) : 45-51.
10.1051/medsci/2021241 -
Motor and non-motor circuit disturbances in early Parkinson disease: which happens first?
Javier Blesa, Guglielmo Foffani, Benjamin Dehay, Erwan Bezard, Jose A. Obeso.
Nat Rev Neurosci. 2021-12-14.
10.1038/s41583-021-00542-9 -
Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques
Marie-Laure Arotcarena, Sandra Dovero, Nathalie Biendon, Nathalie Dutheil, Vincent Planche, Erwan Bezard, Benjamin Dehay.
Front. Bioeng. Biotechnol.. 2021-11-15. 9
10.3389/fbioe.2021.762209 -
Lack of limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes in aged macaques with memory impairment
Morgane Darricau, Marie-Hélène Canron, Marion Bosc, Marie-Laure Arotçarena, Mégane Le Quang, Benjamin Dehay, Erwan Bezard, Vincent Planche.
Neurobiology of Aging. 2021-11-01. 107 : 53-56.
10.1016/j.neurobiolaging.2021.07.009 -
Nucleolipid Acid-Based Nanocarriers Restore Neuronal Lysosomal Acidification Defects
Mathias Brouillard, Philippe Barthélémy, Benjamin Dehay, Sylvie Crauste-Manciet, Valérie Desvergnes.
Front. Chem.. 2021-08-20. 9
10.3389/fchem.2021.736554 -
PLGA-Based Nanoparticles for Neuroprotective Drug Delivery in Neurodegenerative Diseases
Anthony Cunha, Alexandra Gaubert, Laurent Latxague, Benjamin Dehay.
Pharmaceutics. 2021-07-08. 13(7) : 1042.
10.3390/pharmaceutics13071042 -
A New Rise of Non-Human Primate Models of Synucleinopathies
Margaux Teil, Marie-Laure Arotcarena, Benjamin Dehay.
Biomedicines. 2021-03-09. 9(3) : 272.
10.3390/biomedicines9030272 -
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Klionsky DJ et al.
Autophagy. 2021-02.
10.1080/15548627.2020.1797280 -
Comparison of the expression and toxicity of AAV2/9 carrying the human A53T α-synuclein gene in presence or absence of WPRE
Xiuping Sun, Xuan Yu, Ling Zhang, Wenjie Zhao, Manshi Wang, Yu Zhang, Xianglei Li, Ran Gao, Ludivine S. Breger, Sandra Dovero, Gregory Porras, Pierre-Olivier Fernagut, Benjamin Dehay, Erwan Bezard, Chuan Qin.
Heliyon. 2021-02-01. 7(2) : e06302.
10.1016/j.heliyon.2021.e06302 -
Involvement of Autophagy in Levodopa‐Induced Dyskinesia
Michael Feyder, Carina Plewnia, Ori J. Lieberman, Giada Spigolon, Alessandro Piccin, Lidia Urbina, Benjamin Dehay, Qin Li, Per Nilsson, Mikael Altun, Emanuela Santini, David Sulzer, Erwan Bezard, Anders Borgkvist, Gilberto Fisone.
Mov Disord. 2021-01-18.
10.1002/mds.28480 -
Evaluation of blood flow as a route for propagation in experimental synucleinopathy
Xuan Yu, Marine Persillet, Ling Zhang, Yu Zhang, Sun Xiuping, Xianglei Li, Gao Ran, Ludivine S. Breger, Sandra Dovero, Gregory Porras, Benjamin Dehay, Erwan Bezard, Chuan Qin.
Neurobiology of Disease. 2021-01-01. : 105255.
10.1016/j.nbd.2021.105255 -
L‐DOPA regulates α‐synuclein accumulation in experimental parkinsonism
Marc Deffains, Marie‐Hélène Canron, Margaux Teil, Qin Li, Benjamin Dehay, Erwan Bezard, Pierre‐Olivier Fernagut.
Neuropathol Appl Neurobiol. 2020-12-04.
10.1111/nan.12678 -
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease
Nora Bengoa-Vergniory, Emilie Faggiani, Paula Ramos-Gonzalez, Ecem Kirkiz, Natalie Connor-Robson, Liam V. Brown, Ibrar Siddique, Zizheng Li, Siv Vingill, Milena Cioroch, Fabio Cavaliere, Sarah Threlfell, Bradley Roberts, Thomas Schrader, Frank-Gerrit Klärner, Stephanie Cragg, Benjamin Dehay, Gal Bitan, Carlos Matute, Erwan Bezard, Richard Wade-Martins.
Nat Commun. 2020-09-28. 11(1)
10.1038/s41467-020-18689-x -
Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
Federico N. Soria, Chiara Paviolo, Evelyne Doudnikoff, Marie-Laure Arotcarena, Antony Lee, Noémie Danné, Amit Kumar Mandal, Philippe Gosset, Benjamin Dehay, Laurent Groc, Laurent Cognet, Erwan Bezard.
Nat Commun. 2020-07-10. 11(1)
10.1038/s41467-020-17328-9 -
Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction
Zhenwei Yu, Min Shi, Tessandra Stewart, Pierre-Olivier Fernagut, Yang Huang, Chen Tian, Benjamin Dehay, Anzari Atik, Dishun Yang, Francesca De Giorgi, François Ichas, Marie-Hélène Canron, Roberto Ceravolo, Daniela Frosini, Han-Joon Kim, Tao Feng, Wassilios G Meissner, Jing Zhang.
Brain. 2020-05-18.
10.1093/brain/awaa110 -
Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates
Marie-Laure Arotcarena, Sandra Dovero, Alice Prigent, Mathieu Bourdenx, Sandrine Camus, Gregory Porras, Marie-Laure Thiolat, Maddalena Tasselli, Philippe Aubert, Niels Kruse, Brit Mollenhauer, Ines Trigo Damas, Cristina Estrada, Nuria Garcia-Carrillo, Nishant N Vaikath, Omar M A El-Agnaf, Maria Trinidad Herrero, Miquel Vila, Jose A Obeso, Pascal Derkinderen, Benjamin Dehay, Erwan Bezard.
Brain. 2020-05-01. 143(5) : 1462-1475.
10.1093/brain/awaa096 -
Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates
Alexander Maxan, Giacomo Sciacca, Melanie Alpaugh, Zhu Tao, Ludivine Breger, Benjamin Dehay, Zhang Ling, Chuan Qin, Giulia Cisbani, Maria Masnata, Shireen Salem, Steve Lacroix, Abid Oueslati, Erwan Bezard, Francesca Cicchetti.
Neurobiology of Disease. 2020-05-01. : 104951.
10.1016/j.nbd.2020.104951 -
Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
M. Bourdenx, A. Nioche, S. Dovero, M.-L. Arotcarena, S. Camus, G. Porras, M.-L. Thiolat, N. P. Rougier, A. Prigent, P. Aubert, S. Bohic, C. Sandt, F. Laferrière, E. Doudnikoff, N. Kruse, B. Mollenhauer, S. Novello, M. Morari, T. Leste-Lasserre, I. Trigo Damas, M. Goillandeau, C. Perier, C. Estrada, N. Garcia-Carrillo, A. Recasens, N. N. Vaikath, O. M. A. El-Agnaf, M. T. Herrero, P. Derkinderen, M. Vila, J. A. Obeso, B. Dehay, E. Bezard.
Sci. Adv.. 2020-05-01. 6(20) : eaaz9165.
10.1126/sciadv.aaz9165 -
Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates
Philippe Gosset, Alexander Maxan, Melanie Alpaugh, Ludivine Breger, Benjamin Dehay, Zhu Tao, Zhang Ling, Chuan Qin, Giulia Cisbani, Nadia Fortin, Jean-Paul G. Vonsattel, Steve Lacroix, Abid Oueslati, Erwan Bezard, Francesca Cicchetti.
Neurobiology of Disease. 2020-05-01. : 104941.
10.1016/j.nbd.2020.104941 -
Nilotinib Fails to Prevent Synucleinopathy and Cell Loss in a Mouse Model of Multiple System Atrophy
Miguel Lopez-Cuina, Paul A. Guerin, Marie-Hélène Canron, Anna Delamarre, Benjamin Dehay, Erwan Bezard, Wassilios G. Meissner, Pierre-Olivier Fernagut.
Mov Disord. 2020-04-14.
10.1002/mds.28034 -
Synthesis and Intracellular Uptake of Rhodamine–Nucleolipid Conjugates into a Nanoemulsion Vehicle
Anthony Cunha, Geoffrey Prévot, Yannick Mousli, Philippe Barthélémy, Sylvie Crauste-Manciet, Benjamin Dehay, Valérie Desvergnes.
ACS Omega. 2020-03-12. 5(11) : 5815-5823.
10.1021/acsomega.9b03992 -
Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts
Margaux Teil, Marie-Laure Arotcarena, Emilie Faggiani, Florent Laferriere, Erwan Bezard, Benjamin Dehay.
Biomolecules. 2020-03-03. 10(3) : 391.
10.3390/biom10030391 -
Multiple System Atrophy: Recent Developments and Future Perspectives
Wassilios G. Meissner, Pierre‐Olivier Fernagut, Benjamin Dehay, Patrice Péran, Anne Pavy‐Le Traon, Alexandra Foubert‐Samier, Miguel Lopez Cuina, Erwan Bezard, François Tison, Olivier Rascol.
Mov Disord. 2019-11-06.
10.1002/mds.27894 -
Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in non-human primates
M. Bourdenx, A. Nioche, S. Dovero, M.-L. Arotcarena, S. Camus, G. Porras, M.-L. Thiolat, N. P. Rougier, A. Prigent, P. Aubert, S. Bohic, C. Sandt, F. Laferrière, E. Doudnikoff, N. Kruse, B. Mollenhauer, S. Novello, M. Morari, T. Leste-Lasserre, I. Trigo Damas, M. Goillandeau, C. Perier, C. Estrada, N. Garcia-Carrillo, A. Recasens, N. N. Vaikath, O. M. A. El-Agnaf, M. Trinidad Herrero, P. Derkinderen, M. Vila, J. A. Obeso, B. Dehay, E. Bezard.
. 2019-10-31.
10.1101/825216 -
Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies
Marie-Laure Arotcarena, Mathieu Bourdenx, Nathalie Dutheil, Marie-Laure Thiolat, Evelyne Doudnikoff, Sandra Dovero, Andrea Ballabio, Pierre-Olivier Fernagut, Wassilios G. Meissner, Erwan Bezard, Benjamin Dehay.
JCI Insight. 2019-08-22. 4(16)
10.1172/jci.insight.129719 -
Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery
Marie-Laure Arotcarena, Margaux Teil, Benjamin Dehay.
Cells. 2019-06-09. 8(6) : 565.
10.3390/cells8060565 -
Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-related Neurodegenerative Diseases.
Geoffrey Prévot, Federico N. Soria, Marie-Laure Thiolat, Jonathan Daniel, Jean Baptiste Verlhac, Mireille Blanchard-Desce, Erwan Bezard, Philippe Barthélémy, Sylvie Crauste-Manciet, Benjamin Dehay.
Bioconjugate Chem.. 2018-11-13. 29(12) : 4083-4089.
10.1021/acs.bioconjchem.8b00697 -
Are synucleinopathies prion-like disorders?,Les synucléinopathies sont-elles des maladies à prions ?
M.-L. Arotçarena, B. Dehay.
Pratique Neurologique - FMC. 2018-04-01. 9(2) : 145-151.
10.1016/j.praneu.2018.02.006 -
Synaptic Regulator α-Synuclein in Dopaminergic Fibers Is Essentially Required for the Maintenance of Subependymal Neural Stem Cells
Ana Perez-Villalba, M. Salomé Sirerol-Piquer, Germán Belenguer, Raúl Soriano-Cantón, Ana Belén Muñoz-Manchado, Javier Villadiego, Diana Alarcón-Arís, Federico N. Soria, Benjamin Dehay, Erwan Bezard, Miquel Vila, Analía Bortolozzi, Juan José Toledo-Aral, Francisco Pérez-Sánchez, Isabel Fariñas.
J. Neurosci.. 2017-12-07. 38(4) : 814-825.
10.1523/JNEUROSCI.2276-17.2017 -
In vivo models of alpha-synuclein transmission and propagation
Ariadna Recasens, Ayse Ulusoy, Philipp J. Kahle, Donato A. Di Monte, Benjamin Dehay.
Cell Tissue Res. 2017-11-29. 373(1) : 183-193.
10.1007/s00441-017-2730-9 -
In utero delivery of rAAV2/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson’s disease.
L Chansel-Debordeaux, M Bourdenx, S Dovero, V Grouthier, N Dutheil, A Espana, L Groc, C Jimenez, E Bezard, B Dehay.
Gene Ther. 2017-11-16. 24(12) : 801-809.
10.1038/gt.2017.84 -
Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies
Mathieu Bourdenx, Nikolaos Stavros Koulakiotis, Despina Sanoudou, Erwan Bezard, Benjamin Dehay, Anthony Tsarbopoulos.
Progress in Neurobiology. 2017-08-01. 155 : 171-193.
10.1016/j.pneurobio.2015.07.003 -
Autophagy and brain: The case of neurodegenerative diseases,Autophagie et cerveau
Mathieu Bourdenx, Benjamin Dehay.
Med Sci (Paris). 2017-03-01. 33(3) : 268-274.
10.1051/medsci/20173303013 -
What lysosomes actually tell us about Parkinson’s disease?
Mathieu Bourdenx, Benjamin Dehay.
Ageing Research Reviews. 2016-12-01. 32 : 140-149.
10.1016/j.arr.2016.02.008 -
Alpha-synuclein-based models of Parkinson’s disease
B. Dehay, P.-O. Fernagut.
Revue Neurologique. 2016-06-01. 172(6-7) : 371-378.
10.1016/j.neurol.2016.04.003 -
Harnessing the trophic and modulatory potential of statins in a dopaminergic cell line.
Mathieu Schmitt, Benjamin Dehay, Erwan Bezard, F. Javier Garcia-Ladona.
Synapse. 2016-01-06. 70(3) : 71-86.
10.1002/syn.21881 -
Alpha-synuclein spreading in Parkinson’s disease
Ariadna Recasens, Benjamin Dehay.
Front. Neuroanat.. 2014-12-18. 8
10.3389/fnana.2014.00159 -
BAX channel activity mediates lysosomal disruption linked to Parkinson disease
Jordi Bové, Marta Martínez-Vicente, Benjamin Dehay, Celine Perier, Ariadna Recasens, Agnes Bombrun, Bruno Antonsson, Miquel Vila.
Autophagy. 2014-03-26. 10(5) : 889-900.
10.4161/auto.28286 -
Evidence piles up for prion-like propagation mechanisms in synucleinopathies
Benjamin Dehay.
Mov Disord.. 2014-01-02. 29(2) : 187-187.
10.1002/mds.25793 -
Viral vectors in primate research: Examples from Parkinson’s disease research
Grégory Porras, Benjamin Dehay, Erwan Bezard.
Neuromethods. 2013-09-19. : 331-341.
10.1007/978-1-62703-610-8_17 -
Single-molecule approach to find out toxic oligomeric alpa-synuclein species formation
Benjamin Dehay.
Mov. Disord.. 2012-10-01. 27(12) : 1493-1493.
10.1002/mds.25180 -
Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex i deficiency
D Ramonet, C Perier, A Recasens, B Dehay, J Bové, V Costa, L Scorrano, M Vila.
Cell Death Differ. 2012-08-03. 20(1) : 77-85.
10.1038/cdd.2012.95 -
Guidelines for the use and interpretation of assays for monitoring autophagy
Daniel J. Klionsky et al.
Autophagy. 2012-04-01. 8(4) : 445-544.
10.4161/auto.19496 -
New experimental approach for modeling Parkinson’s disease
Benjamin Dehay.
Mov. Disord.. 2012-03-01. 27(3) : 344-344.
10.1002/mds.24933 -
Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells
A. Sánchez-Danés, A. Consiglio, Y. Richaud, I. Rodríguez-Pizà, B. Dehay, M. Edel, J. Bové, M. Memo, M. Vila, A. Raya, J.C. Izpisua Belmonte.
Human Gene Therapy. 2012-01-01. 23(1) : 56-69.
10.1089/hum.2011.054 -
The true nature of α-synuclein unmasked!
Benjamin Dehay.
Mov. Disord.. 2011-11-01. 26(13) : 2324-2324.
10.1002/mds.24009 -
α-synuclein, a prion-like protein
Benjamin Dehay.
Mov. Disord.. 2011-04-01. 26(5) : 774-774.
10.1002/mds.23748 -
Lysosomal membrane permeabilization in Parkinson disease
Miquel Vila, Jordi Bové, Benjamin Dehay, Natalia Rodríguez-Muela, Patricia Boya.
Autophagy. 2011-01-01. 7(1) : 98-100.
10.4161/auto.7.1.13933 -
Pathogenic lysosomal depletion in Parkinson’s disease
B. Dehay, J. Bove, N. Rodriguez-Muela, C. Perier, A. Recasens, P. Boya, M. Vila.
Journal of Neuroscience. 2010-09-15. 30(37) : 12535-12544.
10.1523/JNEUROSCI.1920-10.2010 -
Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins
Celine Perier, Jordi Bové, Benjamin Dehay, Vernice Jackson-Lewis, Peter S. Rabinovitch, Serge Przedborski, Miquel Vila.
Ann Neurol.. 2010-04-06. : n/a-n/a.
10.1002/ana.22034 -
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson’s disease
C. Perier, J. Bove, D.-C. Wu, B. Dehay, D.-K. Choi, V. Jackson-Lewis, S. Rathke-Hartlieb, P. Bouillet, A. Strasser, J. B. Schulz, S. Przedborski, M. Vila.
Proceedings of the National Academy of Sciences. 2007-05-02. 104(19) : 8161-8166.
10.1073/pnas.0609874104 -
Mapping of the epitope of monoclonal antibody 2B4 to the proline-rich region of human Huntingtin, a region critical for aggregation and toxicity
Benjamin Dehay, Chantal Weber, Yvon Trottier, Anne Bertolotti.
Biotechnol. J.. 2007-05-01. 2(5) : 559-564.
10.1002/biot.200600249 -
Critical role of the proline-rich region in Huntingtin for aggregation and cytotoxicity in yeast
Benjamin Dehay, Anne Bertolotti.
J. Biol. Chem.. 2006-09-14. 281(47) : 35608-35615.
10.1074/jbc.M605558200 -
Targeting expression of expanded polyglutamine proteins to the endoplasmic reticulum or mitochondria prevents their aggregation
E. Rousseau, B. Dehay, L. Ben-Haiem, Y. Trottier, M. Morange, A. Bertolotti.
Proceedings of the National Academy of Sciences. 2004-06-21. 101(26) : 9648-9653.
10.1073/pnas.0403015101