Troubles du neurodéveloppement : des mécanismes moléculaires à l’inclusion sociale
Neurodevelopmental disorders are a group of different conditions in which the development of the central nervous system is disturbed and that often have lifelong consequences. Such developmental brain dysfunction can manifest as neuropsychiatric problems (Autism Spectrum Disorders, schizophrenia, fragile-X syndrome, down syndrome…) or impaired motor function, learning, language or non-verbal communication. Numerous developmental processes can go awry, sometimes simultaneously, affecting the generation of the appropriate diversity of neural cell types, their migration to correct sites in the brain and the establishment of precise connectivity with target cells, leading to complex brain and sensory dysfunction(s) and neurological diseases.
In this 3 days symposium, experts from different areas of developmental neuroscience, human neuropsychology, epidemiology, brain imaging and genetics & epigenetics as well as clinicians will address the current state of neurodevelopmental disorders research, and its challenges for human health. We hope that by integrating neurodevelopmental perspectives and basic, translational and clinical approaches, this meeting will promote discussions and exchanges, and a new understanding of the complexity of these pathologies.