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Nano Symposium: Thalamocortical circuits from sensory perception to cognition

Thursday 7 February 2019 / 10:30 - 13:00

Synaptic interactions in the thalamocortical system during sensory processing and behavior

Scientific focus :

While the cortex has long been thought as the ‘cognitive’ headquarter of the brain, the crucial role of its functional interactions with subcortical structures and especially thalamic nuclei are now increasingly acknowledged. Today, two speakers will show how our knowledge of the physiology and role of thalamocortical circuits in sensory perception may be valuable to understand their role in cognitive processes. A combination of electrophysiology, optogenetics and behavioral approaches will showcase how these circuits may act as a bridge from sensory perception to cognition.

CGFB 10h30 / Dr Mehdi Adibi, School of Psychology, The University of New South Wales (UNSW), Sydney

Sensory processing and decision making in dynamic environments Abstract: A fundamental question in systems neuroscience is how the sensory information about the surrounding environment is encoded in the activity of neurons, how this activity is read out by downstream neurons and ultimately how it gives rise to perception and behaviour. We chose to investigate this question in the whisker-mediated touch system of rodents because of its well-established anatomy and exquisite functionality. The whisker system is one of the major channels through which rodents acquire sensory information about their surrounding environment. The response properties of neurons dynamically adjust to the dynamics of the environment and prevailing diet of sensory stimulation. Here, we investigate what are the neuronal computations and underlying mechanisms governing this adaptive information processing, and how in turn how dynamic changes in the environment affects the behaviour. We combine a variety of techniques ranging from in vivo extracellular array recording, loose-cell patch clamp recording/labelling, optogenetics, behavioural and computational approaches to address this question in rodent model system.

11h00 / Alexander Groh

Heidelberg university, Germany / Institute of Physiology and Pathophysiology Im Neuenheimer

The cerebral cortex is the ‘cognitive’ headquarter of the brain and is instrumental for transforming sensory signals into action.

Titre:  Synaptic interactions in the thalamocortical system during sensory processing and behavior
Abstract: But how does the cortex communicate with the rest of the brain to fulfil this function and how are impairments to this communication expressed in brain diseases? Our lab investigates the structure and the functional mechanisms underlying the interplay between the cortex and subcortical networks that give rise to cognitive functions, including sensori-motor transformations, salience encoding and pathological pain. We are leveraging a combination of in vivo deep-brain electrophysiology, optogenetics, synaptic physiology and behavioural approaches in the mouse model system.

 

Coming soon

  1. Seminar – David Stellwagen

    Thursday 20 June 2019 / 15:30

    TNF-mediated synaptic plasticity in the response to stress and reward

  2. Seminar – André Ramos

    Friday 21 June 2019 / 11:30

    Le long (et incertain) chemin entre les comportements liés à l'anxiété et les gènes sous-jacents

  3. Seminar – Manojkumar Saranathan

    Friday 21 June 2019 / 14:30

    Segmentation of thalamic nuclei from 3T MRI with applications

  4. Thesis defense – Sandra Dubes

    Monday 24 June 2019 / 14:30

    miR-124 is required for synaptic scaling induction by controlling the expression of synaptopodin and AMPA receptors in hippocampal neurons

  5. Cajal course : Biosensors and actuators for cellular and systems neuroscience

    Tuesday 25 June 2019 - Tuesday 9 July 2019

    Talks are open to everyone

Details

Date:
Thursday 7 February 2019
Time:
10:30 - 13:00
Event Category:

Venue

CGFB
38 rue Albert Marquet
Bordeaux, 33000 France