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Conference Labex Trail – Goran Angelovski

Friday 28 June 2019 / 14:30

Molecular fMRI with Bioresponsive Probes, Molecular fMRI with Bioresponsive Probes

Venue : CGFB

Goran Angelovski
Priv.-Doz. Dr. MR Neuroimaging Agents,
MPI for Biological Cybernetics,
Tuebingen, Germany

Invited by Yannick Crémillieux
Université de Bordeaux

Goran ANGELOVSKI received a diploma degree from the University in Belgrade, Ph.D. degree from the University in Dortmund and venia legendi (habilitation) from the University of Tuebingen. He is currently a research group leader at the MPI for Biological Cybernetics in Tuebingen. His research interests include the development of responsive molecular probes for functional MRI applications, from their preparation, to the final in vivo utilization.


Molecular fMRI with Bioresponsive Probes Bioresponsive or smart contrast agents (SCAs) can substantially improve specificity of magnetic resonance imaging (MRI) in studying processes on molecular and cellular level. These probes are capable of alternating the MR image contrast upon change in the local environment, thus reporting the occurrence of a particular physiological or pathological process. Over the past several years, we developed a series of paramagnetic and biocompatible SCAs that strongly respond to calcium ions and amino acid neurotransmitters. Moreover, we validated their functionality in various MRI experiments in vitro, ex vivo, as well as in vivo. The most prominent example is utilization of a calcium-sensitive MRI probe for early detection and monitoring of brain ischemia. Wider involvement of this novel fMRI methodology can offer excellent perspectives for direct visualization and mapping of neural activity in unprecedented fashion.

Coming soon

  1. Monthly conference (PhD seminar series) – Laurent Bourdieu

    Friday 6 September 2019 / 11:30

    Fast 3D imaging of neuronal activity in visual cortex across multiple layers in awake mice

  2. Cajal lectures : Whole brain imaging

    Monday 9 September 2019 - Friday 27 September 2019

    Free entrance lectures / Venue: CGFB

  3. Seminar – Francesco Papaleo

    Friday 13 September 2019 / 11:30

    Bottom-Up and Top-Down Control of Emotion Recognition.

  4. LabEx TRAIL scientific day

    Monday 16 September 2019 / 14:00 - 18:00

    Dedicated to brain connectivity.

  5. Synapse Day

    Tuesday 17 September 2019

    Centre Broca Nouvelle-Aquitaine

Conférence internationale : REWARD

Du 2 au 4 octobre

L’événement en un coup d’oeil :
télécharger le livret (programme,
inscription, soumission d’abstract…)



Friday 28 June 2019
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