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Conférence Labex Trail – Goran Angelovski

vendredi 28 juin 2019 / 14:30

Molecular fMRI with Bioresponsive Probes

Lieu : CGFB

Goran Angelovski
Priv.-Doz. Dr. MR Neuroimaging Agents,
MPI for Biological Cybernetics,
Tuebingen, Germany

Invité par Yannick Crémillieux
Université de Bordeaux

Goran ANGELOVSKI received a diploma degree from the University in Belgrade, Ph.D. degree from the University in Dortmund and venia legendi (habilitation) from the University of Tuebingen. He is currently a research group leader at the MPI for Biological Cybernetics in Tuebingen. His research interests include the development of responsive molecular probes for functional MRI applications, from their preparation, to the final in vivo utilization.


Molecular fMRI with Bioresponsive Probes Bioresponsive or smart contrast agents (SCAs) can substantially improve specificity of magnetic resonance imaging (MRI) in studying processes on molecular and cellular level. These probes are capable of alternating the MR image contrast upon change in the local environment, thus reporting the occurrence of a particular physiological or pathological process. Over the past several years, we developed a series of paramagnetic and biocompatible SCAs that strongly respond to calcium ions and amino acid neurotransmitters. Moreover, we validated their functionality in various MRI experiments in vitro, ex vivo, as well as in vivo. The most prominent example is utilization of a calcium-sensitive MRI probe for early detection and monitoring of brain ischemia. Wider involvement of this novel fMRI methodology can offer excellent perspectives for direct visualization and mapping of neural activity in unprecedented fashion.


  1. Conférence mensuelle (PhD seminar series) – Laurent Bourdieu

    vendredi 6 septembre 2019 / 11:30

    Fast 3D imaging of neuronal activity in visual cortex across multiple layers in awake mice

  2. Cajal lectures : Whole brain imaging

    lundi 9 septembre 2019 - vendredi 27 septembre 2019

    Free entrance lectures / Venue: CGFB

  3. Séminaire – Francisco Papaleo

    vendredi 13 septembre 2019 / 11:30

    Bottom-Up and Top-Down Control of Emotion Recognition.

  4. LabEx TRAIL scientific day

    lundi 16 septembre 2019 / 14:00 - 18:00

    Dedicated to brain connectivity.

  5. Journée Synapse

    mardi 17 septembre 2019

    Centre Broca Nouvelle-Aquitaine

Conférence internationale : REWARD

Du 2 au 4 octobre

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Date :
vendredi 28 juin 2019
Heure :
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