Agata Nowacka et al team Choquet in Neuron

When synapses adjust information transfer thanks to mobile receptors

Faced with rapid series of nerve signals, the brain must fine-tune the transmission of information. A study published in Neuron shows that this adjustment relies on the mobility of receptors present on the surface of neurons.

By renewing themselves within the synapses, these receptors allow for the maintenance of effective communication during rapid stimulation, while modulating the response according to the type of synapse. This mechanism directly links information processing, synaptic plasticity, and learning.

For more information

Synapse-specific and plasticity-regulated AMPA receptor mobility tunes synaptic integration, Agata Nowacka, Angela M. Getz, Hanna L. Zieger, Maxime Malivert, Diogo Bessa-Neto, Elisabete Augusto, Christelle Breillat, Sophie Daburon, Cécile Lemoigne, Sébastien Marais, Mathieu Ducros, Alexandre Favereaux, Andrew C. Penn, Richard Naud, Matthieu Sainlos, Daniel Choquet.

Neuron, February 4th 2026.

Contact

Daniel Choquet
CNRS Researcher
GPR  director – Team leader – BIC Director
Team: Dynamic organization and function of synapses

Copyrights figure: Agata Nowacka, Angela Getz, Daniel Choquet