Olivier Thoumine

Publications

• High-affinity detection of biotinylated endogenous neuroligin-1 at excitatory and inhibitory synapses using a tagged knock-in mouse
  Charles Ducrot, Adèle Drouet, Béatrice Tessier, Chloé Desquines, Tiffany Cloâtre, Rania-Cérine Mazouzi, Florian Levet, Alexandre Favereaux, Mathieu Letellier, Olivier Thoumine.
  Proc. Natl. Acad. Sci. U.S.A.. 2025-05-27. 122(22)
  10.1073/pnas.2411669122
• LRRTM2 controls presynapse nano-organization and AMPA receptor sub-positioning through Neurexin-binding interface
  Konstantina Liouta, Malgorzata Lubas, Vasika Venugopal, Julia Chabbert, Caroline Jeannière, Candice Diaz, Matthieu Munier, Béatrice Tessier, Stéphane Claverol, Alexandre Favereaux, Matthieu Sainlos, Joris de Wit, Mathieu Letellier, Olivier Thoumine, Ingrid Chamma.
  Nat Commun. 2024-10-11. 15(1)
  10.1038/s41467-024-53090-y
• Protocol for matching protein localization to synapse morphology in primary rat neurons by correlative super-resolution microscopy
  Tiffany Cloâtre, Magali Mondin, Jean-Baptiste Sibarita, Florian Levet, Olivier Thoumine.
  STAR Protocols. 2024-09-01. 5(3) : 103160.
  10.1016/j.xpro.2024.103160
• Neuroligin-1 dependent phosphotyrosine signaling in excitatory synapse differentiation
  Zsófia Szíber, Adèle Drouet, Magali Mondin, Florian Levet, Olivier Thoumine.
  Front. Mol. Neurosci.. 2024-05-15. 17
  10.3389/fnmol.2024.1359067
• miR ‐124‐dependent tagging of synapses by synaptopodin enables input‐specific homeostatic plasticity
  Sandra Dubes, Anaïs Soula, Sébastien Benquet, Béatrice Tessier, Christel Poujol, Alexandre Favereaux, Olivier Thoumine, Mathieu Letellier.
  The EMBO Journal. 2022-07-25.
  10.15252/embj.2021109012
• MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior.
  Andrea Toledo, Mathieu Letellier, Giorgia Bimbi, Béatrice Tessier, Sophie Daburon, Alexandre Favereaux, Ingrid Chamma, Kristel Vennekens, Jeroen Vanderlinden, Matthieu Sainlos, Joris de Wit, Daniel Choquet, Olivier Thoumine.
  eLife. 2022-05-09. 11
  10.7554/elife.75233
• High-Resolution Fluorescence Imaging Combined With Computer Simulations to Quantitate Surface Dynamics and Nanoscale Organization of Neuroligin-1 at Synapses.
  Matthieu Lagardère, Adèle Drouet, Matthieu Sainlos, Olivier Thoumine.
  Front. Synaptic Neurosci.. 2022-04-25. 14
  10.3389/fnsyn.2022.835427
• Convergence of adenosine and GABA signaling for synapse stabilization during development.
  Ferran Gomez-Castro, Stefania Zappettini, Jessica C. Pressey, Carla G. Silva, Marion Russeau, Nicolas Gervasi, Marta Figueiredo, Claire Montmasson, Marianne Renner, Paula M. Canas, Francisco Q. Gonçalves, Sofia Alçada-Morais, Eszter Szabó, Ricardo J. Rodrigues, Paula Agostinho, Angelo R. Tomé, Ghislaine Caillol, Olivier Thoumine, Xavier Nicol, Christophe Leterrier, Rafael Lujan, Shiva K. Tyagarajan, Rodrigo A. Cunha, Monique Esclapez, Christophe Bernard, Sabine Lévi.
  Science. 2021-11-05. 374(6568)
  10.1126/science.abk2055
• Role of regulatory C‐terminal motifs in synaptic confinement of LRRTM2
  Konstantina Liouta, Julia Chabbert, Sebastien Benquet, Béatrice Tessier, Vincent Studer, Matthieu Sainlos, Joris De Wit, Olivier Thoumine, Ingrid Chamma.
  Biol. Cell. 2021-09-27.
  10.1111/boc.202100026
• SlitC-PlexinA1 mediates iterative inhibition for orderly passage of spinal commissural axons through the floor plate.
  Hugo Ducuing, Thibault Gardette, Aurora Pignata, Karine Kindbeiter, Muriel Bozon, Olivier Thoumine, Céline Delloye-Bourgeois, Servane Tauszig-Delamasure, Valerie Castellani.
  eLife. 2020-12-21. 9
  10.7554/elife.63205
• FluoSim: simulator of single molecule dynamics for fluorescence live-cell and super-resolution imaging of membrane proteins.
  Matthieu Lagardère, Ingrid Chamma, Emmanuel Bouilhol, Macha Nikolski, Olivier Thoumine.
  Sci Rep. 2020-11-17. 10(1)
  10.1038/s41598-020-75814-y
• Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity
  Shinichiro Oku, Huijuan Feng, Steven Connor, Andrea Toledo, Peng Zhang, Yue Zhang, Olivier Thoumine, Chaolin Zhang, Ann Marie Craig.
  eLife. 2020-09-11. 9
  10.7554/elife.58668
• Optogenetic control of excitatory post-synaptic differentiation through neuroligin-1 tyrosine phosphorylation
  Mathieu Letellier, Matthieu Lagardère, Béatrice Tessier, Harald Janovjak, Olivier Thoumine.
  eLife. 2020-04-23. 9
  10.7554/elife.52027
• FluoSim: simulator of single molecule dynamics for fluorescence live-cell and super-resolution imaging of membrane proteins
  Matthieu Lagardère, Ingrid Chamma, Emmanuel Bouilhol, Macha Nikolski, Olivier Thoumine.
  . 2020-02-06.
  10.1101/2020.02.06.937045
• Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth
  Steve Dos-Santos Carvalho, Maite M Moreau, Yeri Esther Hien, Michael Garcia, Nathalie Aubailly, Deborah J Henderson, Vincent Studer, Nathalie Sans, Olivier Thoumine, Mireille Montcouquiol.
  eLife. 2020-01-07. 9
  10.7554/eLife.51822
• miRNA-Dependent Control of Homeostatic Plasticity in Neurons
  Sandra Dubes, Alexandre Favereaux, Olivier Thoumine, Mathieu Letellier.
  Front. Cell. Neurosci.. 2019-12-05. 13
  10.3389/fncel.2019.00536
• A super-resolution platform for correlative live single-molecule imaging and STED microscopy
  V. V. G. Krishna Inavalli, Martin O. Lenz, Corey Butler, Julie Angibaud, Benjamin Compans, Florian Levet, Jan Tønnesen, Olivier Rossier, Gregory Giannone, Olivier Thoumine, Eric Hosy, Daniel Choquet, Jean-Baptiste Sibarita, U. Valentin Nägerl.
  Nat Methods. 2019-10-21.
  10.1038/s41592-019-0611-8
• A Spatiotemporal Sequence of Sensitization to Slits and Semaphorins Orchestrates Commissural Axon Navigation.
  Aurora Pignata, Hugo Ducuing, Leila Boubakar, Thibault Gardette, Karine Kindbeiter, Muriel Bozon, Servane Tauszig-Delamasure, Julien Falk, Olivier Thoumine, Valérie Castellani.
  Cell Reports. 2019-10-01. 29(2) : 347-362.e5.
  10.1016/j.celrep.2019.08.098
• TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering
  Edoardo Moretto, Anna Longatti, Luca Murru, Ingrid Chamma, Alessandro Sessa, Jonathan Zapata, Eric Hosy, Matthieu Sainlos, Julien Saint-Pol, Eric Rubinstein, Daniel Choquet, Vania Broccoli, Giampietro Schiavo, Olivier Thoumine, Maria Passafaro.
  Cell Reports. 2019-10-01. 29(5) : 1130-1146.e8.
  10.1016/j.celrep.2019.09.051
• Differential role of pre- and postsynaptic neurons in the activity-dependent control of synaptic strengths across dendrites
  Mathieu Letellier, Florian Levet, Olivier Thoumine, Yukiko Goda.
  PLoS Biol. 2019-06-05. 17(6) : e2006223.
  10.1371/journal.pbio.2006223
• Biophysical mechanisms underlying the membrane trafficking of synaptic adhesion molecules.
  Ingrid Chamma, Matthieu Sainlos, Olivier Thoumine.
  Neuropharmacology. 2019-03-01.
  10.1016/j.neuropharm.2019.02.037
• A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation
  Mathieu Letellier, Zsófia Szíber, Ingrid Chamma, Camille Saphy, Ioanna Papasideri, Béatrice Tessier, Matthieu Sainlos, Katalin Czöndör, Olivier Thoumine.
  Nat Commun. 2018-09-28. 9(1)
  10.1038/s41467-018-06220-2
• A Triad of Crystals Sheds Light on MDGA Interference with Neuroligation.
  Olivier Thoumine, Pascale Marchot.
  Neuron. 2017-08-01. 95(4) : 729-732.
  10.1016/j.neuron.2017.08.001
• Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome.
  Stephanie A. Mauriac, Yeri E. Hien, Jonathan E. Bird, Steve Dos-Santos Carvalho, Ronan Peyroutou, Sze Chim Lee, Maite M. Moreau, Jean-Michel Blanc, Aysegul Geyser, Chantal Medina, Olivier Thoumine, Sandra Beer-Hammer, Thomas B. Friedman, Lukas Rüttiger, Andrew Forge, Bernd Nürnberg, Nathalie Sans, Mireille Montcouquiol.
  Nat Comms. 2017-04-07. 8 : 14907.
  10.1038/ncomms14907
• Optimized labeling of membrane proteins for applications to super-resolution imaging in confined cellular environments using monomeric streptavidin
  Ingrid Chamma, Olivier Rossier, Grégory Giannone, Olivier Thoumine, Matthieu Sainlos.
  Nat Protoc. 2017-03-09. 12(4) : 748-763.
  10.1038/nprot.2017.010
• Synaptogenic Assays Using Neurons Cultured on Micropatterned Substrates.
  Katalin Czöndör, Olivier Thoumine.
  Methods in Molecular Biology. 2016-12-11. : 29-44.
  10.1007/978-1-4939-6688-2_3
• Synaptogenic Assays Using Neurons Cultured on Micropatterned Substrates.
  Katalin Czöndör, Olivier Thoumine.
  Methods in Molecular Biology. 2016-12-11. : 29-44.
  10.1007/978-1-4939-6688-2_3
• Nanoscale organization of synaptic adhesion proteins revealed by single-molecule localization microscopy
  Ingrid Chamma, Florian Levet, Jean-Baptiste Sibarita, Matthieu Sainlos, Olivier Thoumine.
  Neurophoton. 2016-11-03. 3(4) : 041810.
  10.1117/1.NPh.3.4.041810
• Two-tiered coupling between flowing actin and immobilized N-cadherin/catenin complexes in neuronal growth cones
  Mikael Garcia, Cécile Leduc, Matthieu Lagardère, Amélie Argento, Jean-Baptiste Sibarita, Olivier Thoumine.
  Proc Natl Acad Sci USA. 2015-05-18. 112(22) : 6997-7002.
  10.1073/pnas.1423455112
• Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion.
  Anaël Chazeau, Amine Mehidi, Deepak Nair, Jérémie J Gautier, Cécile Leduc, Ingrid Chamma, Frieda Kage, Adel Kechkar, Olivier Thoumine, Klemens Rottner, Daniel Choquet, Alexis Gautreau, Jean‐Baptiste Sibarita, Grégory Giannone.
  EMBO J.. 2014-10-07. 33(23) : 2745-2764.
  10.15252/embj.201488837
• Micropatterned substrates coated with neuronal adhesion molecules for high-content study of synapse formation.
  Katalin Czöndör, Mikael Garcia, Amélie Argento, Audrey Constals, Christelle Breillat, Béatrice Tessier, Olivier Thoumine.
  Nat Commun. 2013-08-12. 4(1)
  10.1038/ncomms3252
• Assembly of synapses: biomimetic assays to control neurexin/neuroligin interactions at the neuronal surface.
  Magali Mondin, Béatrice Tessier, Olivier Thoumine.
  Current Protocols in Neuroscience. 2013-07-01. 64(1)
  10.1002/0471142301.ns0219s64
• Biophysical mechanisms regulating AMPA receptor accumulation at synapses.
  Katalin Czöndör, Olivier Thoumine.
  Brain Research Bulletin. 2013-04-01. 93 : 57-68.
  10.1016/j.brainresbull.2012.11.001
• Interplay between adhesion turnover and cytoskeleton dynamics in the control of growth cone migration.
  Olivier Thoumine.
  Cell Adhesion & Migration. 2008-10-01. 2(4) : 263-267.
  10.4161/cam.2.4.7274
• Predicting the kinetics of cell spreading.
  Thomas Frisch, Olivier Thoumine.
  Journal of Biomechanics. 2002-08-01. 35(8) : 1137-1141.
  10.1016/s0021-9290(02)00075-1
• Contribution of the nucleus to the mechanical properties of endothelial cells.
  Nathalie Caille, Olivier Thoumine, Yanik Tardy, Jean-Jacques Meister.
  Journal of Biomechanics. 2002-02-01. 35(2) : 177-187.
  10.1016/s0021-9290(01)00201-9
• Dynamics of adhesive rupture between fibroblasts and fibronectin: microplate manipulations and deterministic model.
  Olivier Thoumine, Jean-Jacques Meister.
  Eur Biophys J. 2000-09-22. 29(6) : 409-419.
  10.1007/pl00006648
• Short-term binding of fibroblasts to fibronectin: optical tweezers experiments and probabilistic analysis.
  Olivier Thoumine, Pierre Kocian, Arlette Kottelat, Jean-Jacques Meister.
  European Biophysics Journal. 2000-09-22. 29(6) : 398-408.
  10.1007/s002490000087
• A probabilistic model for ligand-cytoskeleton transmembrane adhesion: predicting the behavior of microspheres on the surface of migrating cells.
  OLIVIER THOUMINE, JEAN-JACQUES MEISTER.
  Journal of Theoretical Biology. 2000-06-01. 204(3) : 381-392.
  10.1006/jtbi.2000.2024
• Changes in the mechanical properties of fibroblasts during spreading: a micromanipulation study.
  O. Thoumine, Olivier Cardoso, Jean-Jacques Meister.
  European Biophysics Journal. 1999-03-09. 28(3) : 222-234.
  10.1007/s002490050203
• Microplates: a new tool for manipulation and mechanical perturbation of individual cells.
  Olivier Thoumine, Albrecht Ott, Olivier Cardoso, Jean-Jacques Meister.
  Journal of Biochemical and Biophysical Methods. 1999-02-01. 39(1-2) : 47-62.
  10.1016/s0165-022x(98)00052-9
• Time scale dependent viscoelastic and contractile regimes in fibroblasts probed by microplate manipulation.
  O. Thoumine, A. Ott.
  Journal of Cell Science. 1997-09-01. 110(17) : 2109-2116.
  10.1242/jcs.110.17.2109
• Comparison of the mechanical properties of normal and transformed fibroblasts.
  O THOUMINE, A OTT.
  Biorheology. 1997-07-01. 34(4-5) : 309-326.
  10.1016/s0006-355x(98)00007-9
• Critical centrifugal forces induce adhesion rupture or structural reorganization in cultured cells.
  Olivier Thoumine, Albrecht Ott, Daniel Louvard.
  Cell Motil. Cytoskeleton. 1996-01-01. 33(4) : 276-287.
  10.1002/(sici)1097-0169(1996)33:4<276::aid-cm4>3.0.co;2-7
• Influence of adhesion and cytoskeletal integrity on fibroblast traction.
  Olivier Thoumine, Albrecht Ott.
  Cell Motil. Cytoskeleton. 1996-01-01. 35(3) : 269-280.
  10.1002/(sici)1097-0169(1996)35:3<269::aid-cm8>3.0.co;2-3
• Elongation of confluent endothelial cells in culture: the importance of fields of force in the associated alterations of their cytoskeletal structure.
  Olivier Thoumine, Thierry Ziegler, Peggy R. Girard, Robert M. Nerem.
  Experimental Cell Research. 1995-08-01. 219(2) : 427-441.
  10.1006/excr.1995.1249
• Oscillatory shear stress and hydrostatic pressure modulate cell-matrix attachment proteins in cultured endothelial cells.
  Olivier Thoumine, Robert M. Nerem, Feggy R. Girard.
  In Vitro Cell Dev Biol - Animal. 1995-01-01. 31(1) : 45-54.
  10.1007/bf02631337