Cyril Herry
Chef d'équipe
Directeur de recherche / INSERM/ Contact
+33 5 57 57 37 26
www.orcid.org/0000-0003-2973-0843
/ Adresse
Neurocentre Magendie - INSERM U 1215 - 146, rue Léo Saignat - 33077 Bordeaux
Cyril Herry est Directeur de recherche au Neurocentre Magendie (INSERM U1215 et université de Bordeaux) et neurophysiologiste. Ses recherches portent sur l’identification des circuits neuronaux de la peur et de l’anxiété par la mise en jeu d’approches neuroanatomiques, électrophysiologiques et comportementales. Il est l’auteur de nombreuses publications scientifiques de haut niveau et son travail a été reconnu par l’obtention de prix de l’Académie Nationale de Science et de Médecine. Ses recherches actuelles se concentrent sur l’identification de marqueurs physiologiques de la peur et de l’anxiété chez l’homme et l’animal dans le but de développer de nouvelles approches thérapeutiques ciblées des troubles anxieux.
Publications
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Genetic labeling of embryonically-born dentate granule neurons in young mice using the PenkCre mouse line
Pierre Mortessagne, Estelle Cartier, Maddalena Balia, Murielle Fèvre, Fiona Corailler, Cyril Herry, Djoher Nora Abrous, Arne Battefeld, Emilie Pacary.
Sci Rep. 2024-02-29. 14(1)
10.1038/s41598-024-55299-9 -
CA3 hippocampal synaptic plasticity supports ripple physiology during memory consolidation
Hajer El Oussini, Chun-Lei Zhang, Urielle François, Cecilia Castelli, Aurélie Lampin-Saint-Amaux, Marilyn Lepleux, Pablo Molle, Legeolas Velez, Cyril Dejean, Frederic Lanore, Cyril Herry, Daniel Choquet, Yann Humeau.
Nat Commun. 2023-12-14. 14(1)
10.1038/s41467-023-42969-x -
Prefrontal circuits encode both general danger and specific threat representations
Mario Martin-Fernandez, Ana Paula Menegolla, Guillem Lopez-Fernandez, Nanci Winke, Daniel Jercog, Ha-Rang Kim, Delphine Girard, Cyril Dejean, Cyril Herry.
Nat Neurosci. 2023-10-30.
10.1038/s41593-023-01472-8 -
Integrating operant behavior and fiber photometry with the open-source python library Pyfiber
Dana Conlisk, Matias Ceau, Jean-François Fiancette, Nanci Winke, Elise Darmagnac, Cyril Herry, Véronique Deroche-Gamonet.
Sci Rep. 2023-10-02. 13(1)
10.1038/s41598-023-43565-1 -
Axo-axonic cells in neuropsychiatric disorders: a systematic review
Juliette Vivien, Anass El Azraoui, Cloé Lheraux, Frederic Lanore, Bruno Aouizerate, Cyril Herry, Yann Humeau, Thomas C. M. Bienvenu.
Front. Cell. Neurosci.. 2023-06-26. 17
10.3389/fncel.2023.1212202 -
Dopamine enhances population coding of fear in prefrontal cortex
Jeremy Lesas, Feugas Pierre, Cyril Herry, Cyril Dejean.
PrePrint bioRxiv. 2023-01-18.
10.1101/2023.01.17.524376 -
Decoding defensive systems.
Cyril Herry, Daniel Jercog.
Current Opinion in Neurobiology. 2022-10-01. 76 : 102600.
10.1016/j.conb.2022.102600 -
Pyfiber: an open source python library that facilitates the merge of operant behavior and fiber photometry- focus on intravenous self-administration
Dana Conlisk, Matias Ceau, Jean-François Fiancette, Nanci Winke, Elise Darmagnac, Cyril Herry, Véronique Deroche-Gamonet.
. 2022-09-05.
10.1101/2022.09.02.506312 -
Brainstem somatostatin-expressing cells promote analgesia during negative emotional states
Nanci Winke, Franck Aby, Daniel Jercog, Delphine Girard, Zoé Grivet, Marc Landry, Laia Castell, Emmanuel Valjent, Stéphane Valerio, Pascal Fossat, Cyril Herry.
. 2022-08-26.
10.21203/rs.3.rs-1975119/v1 -
Switch of serotonergic descending inhibition into facilitation by a spinal chloride imbalance in neuropathic pain
Franck Aby, Louis-Etienne Lorenzo, Zoé Grivet, Rabia Bouali-Benazzouz, Hugo Martin, Stéphane Valerio, Sara Whitestone, Dominique Isabel, Walid Idi, Otmane Bouchatta, Philippe De Deurwaerdere, Antoine G. Godin, Cyril Herry, Xavier Fioramonti, Marc Landry, Yves De Koninck, Pascal Fossat.
Sci. Adv.. 2022-07-29. 8(30)
10.1126/sciadv.abo0689 -
Brainstem somatostatin-expressing cells control the emotional regulation of pain behavior
Nanci Winke, Frank Aby, Daniel Jercog, Grivet Zoé, Delphine Girard, Marc Landry, Laia Castell, Emmanuel Valjent, Stephane Valerio, Pascal Fossat, Cyril Herry.
. 2022-01-22.
10.1101/2022.01.20.476899 -
Basal amygdala inputs to the medial prefrontal cortex mediate fear memory strengthening
Einar Ö. Einarsson, Africa Flores, Daniel Jercog, Cyril Herry.
. 2022-01-21.
10.1101/2022.01.20.477064 -
The temporal origin of dentate granule neurons dictates their role in spatial memory
Nuria Masachs, Vanessa Charrier, Fanny Farrugia, Valerie Lemaire, Nicolas Blin, Wilfrid Mazier, Sophie Tronel, Marie-Françoise Montaron, Shaoyu Ge, Giovanni Marsicano, Daniela Cota, Véronique Deroche-Gamonet, Cyril Herry, Djoher Nora Abrous.
Mol Psychiatry. 2021-09-15.
10.1038/s41380-021-01276-x -
Dynamical prefrontal population coding during defensive behaviours
Daniel Jercog, Nanci Winke, Kibong Sung, Mario Martin Fernandez, Claire Francioni, Domitille Rajot, Julien Courtin, Fabrice Chaudun, Pablo E. Jercog, Stephane Valerio, Cyril Herry.
Nature. 2021-07-14. 595(7869) : 690-694.
10.1038/s41586-021-03726-6 -
Central amygdala micro-circuits mediate fear extinction
Nigel Whittle, Jonathan Fadok, Kathryn P. MacPherson, Robin Nguyen, Paolo Botta, Steffen B. E. Wolff, Christian Müller, Cyril Herry, Philip Tovote, Andrew Holmes, Nicolas Singewald, Andreas Lüthi, Stéphane Ciocchi.
Nat Commun. 2021-07-06. 12(1)
10.1038/s41467-021-24068-x -
The advent of fear conditioning as an animal model of post-traumatic stress disorder: Learning from the past to shape the future of PTSD research
Thomas C.M. Bienvenu, Cyril Dejean, Daniel Jercog, Bruno Aouizerate, Maël Lemoine, Cyril Herry.
Neuron. 2021-06-01.
10.1016/j.neuron.2021.05.017 -
Breathing-driven prefrontal oscillations regulate maintenance of conditioned-fear evoked freezing independently of initiation
Sophie Bagur, Julie M. Lefort, Marie M. Lacroix, Gaëtan de Lavilléon, Cyril Herry, Mathilde Chouvaeff, Clara Billand, Hélène Geoffroy, Karim Benchenane.
Nat Commun. 2021-05-10. 12(1)
10.1038/s41467-021-22798-6 -
Changes of Neuronal Activity in the Prefrontal Cortex Related to the Expression and Extinction of Conditioned Fear Responses
Cyril Herry, René Garcia.
Prefrontal Cortex: From Synaptic Plasticity to Cognition. . : 131-151.
10.1007/1-4020-7949-4_6 -
Dissociation of fear initiation and maintenance by breathing-driven prefrontal oscillations
Sophie Bagur, Julie M. Lefort, Marie M. Lacroix, Gaëtan de Lavilléon, Cyril Herry, Clara Billand, Hélène Geoffroy, Karim Benchenane.
. 2018-11-12.
10.1101/468264 -
Neuronal coding mechanisms mediating fear behavior
Robert R Rozeske, Cyril Herry.
Current Opinion in Neurobiology. 2018-10-01. 52 : 60-64.
10.1016/j.conb.2018.04.017 -
Prefrontal-Periaqueductal Gray-Projecting Neurons Mediate Context Fear Discrimination
Robert R. Rozeske, Daniel Jercog, Nikolaos Karalis, Fabrice Chaudun, Suzana Khoder, Delphine Girard, Nânci Winke, Cyril Herry.
Neuron. 2018-02-01. 97(4) : 898-910.e6.
10.1016/j.neuron.2017.12.044 -
Protocols to Study Declarative Memory Formation in Mice and Humans: Optogenetics and Translational Behavioral Approaches
Azza Sellami, Alice Abed, Laurent Brayda-Bruno, Nicole Etchamendy, Stéphane Valério, Marie Oulé, Laura Pantaléon, Valérie Lamothe, Mylène Potier, Katy Bernard, Maritza Jabourian, Cyril Herry, Nicole Mons, Aline Marighetto.
BIO-PROTOCOL. 2018-01-01. 8(12)
10.21769/bioprotoc.2888 -
Temporal binding function of dorsal CA1 is critical for declarative memory formation
Azza Sellami, Alice Shaam Al Abed, Laurent Brayda-Bruno, Nicole Etchamendy, Stéphane Valério, Marie Oulé, Laura Pantaléon, Valérie Lamothe, Mylène Potier, Katy Bernard, Maritza Jabourian, Cyril Herry, Nicole Mons, Pier-Vincenzo Piazza, Howard Eichenbaum, Aline Marighetto.
Proc Natl Acad Sci USA. 2017-09-05. 114(38) : 10262-10267.
10.1073/pnas.1619657114 -
Facilitation of Contextual Fear Extinction by Orexin-1 Receptor Antagonism Is Associated with the Activation of Specific Amygdala Cell Subpopulations.
África Flores, Cyril Herry, Rafael Maldonado, Fernando Berrendero.
International Journal of Neuropsychopharmacology. 2017-04-27. 20(8) : 654-659.
10.1093/ijnp/pyx029 -
Blood on the Tracks: Two Pathways for Predation
Robert R. Rozeske, Cyril Herry.
Cell. 2017-01-01. 168(1-2) : 17-19.
10.1016/j.cell.2016.12.042 -
Prefrontal neuronal assemblies temporally control fear behaviour
Cyril Dejean, Julien Courtin, Nikolaos Karalis, Fabrice Chaudun, Hélène Wurtz, Thomas C. M. Bienvenu, Cyril Herry.
Nature. 2016-07-01. 535(7612) : 420-424.
10.1038/nature18630 -
Midbrain circuits for defensive behaviour
Philip Tovote, Maria Soledad Esposito, Paolo Botta, Fabrice Chaudun, Jonathan P. Fadok, Milica Markovic, Steffen B. E. Wolff, Charu Ramakrishnan, Lief Fenno, Karl Deisseroth, Cyril Herry, Silvia Arber, Andreas Lüthi.
Nature. 2016-06-01. 534(7606) : 206-212.
10.1038/nature17996 -
Preventing long-lasting fear recovery using bilateral alternating sensory stimulation: A translational study.
H. Wurtz, M. El-Khoury-Malhame, F.H. Wilhelm, T. Michael, E.M. Beetz, J. Roques, E. Reynaud, J. Courtin, S. Khalfa, C. Herry.
Neuroscience. 2016-05-01. 321 : 222-235.
10.1016/j.neuroscience.2015.06.012 -
4-Hz oscillations synchronize prefrontal–amygdala circuits during fear behavior
Nikolaos Karalis, Cyril Dejean, Fabrice Chaudun, Suzana Khoder, Robert R Rozeske, Hélène Wurtz, Sophie Bagur, Karim Benchenane, Anton Sirota, Julien Courtin, Cyril Herry.
Nat Neurosci. 2016-02-15. 19(4) : 605-612.
10.1038/nn.4251 -
Neuronal Circuits for Fear Expression and Recovery: Recent Advances and Potential Therapeutic Strategies
Dejean C, Courtin J, Rozeske RR, Bonnet MC, Dousset V, Michelet T, Herry C..
Biol Psychiatry. 2015-09-01. 78(5) : 298-306.
10.1016/j.biopsych.2015.03.017 -
Encoding of fear learning and memory in distributed neuronal circuits
Cyril Herry, Joshua P Johansen.
Nat Neurosci. 2014-11-21. 17(12) : 1644-1654.
10.1038/nn.3869 -
Comportement de peur : rôle des interneurones exprimant la parvalbumine du cortex préfrontal médian
Julien Courtin, Cyril Dejean, Cyril Herry.
Med Sci (Paris). 2014-11-01. 30(11) : 943-945.
10.1051/medsci/20143011004 -
Prefrontal neuronal circuits of contextual fear conditioning.
R. R. Rozeske, S. Valerio, F. Chaudun, C. Herry.
Genes, Brain and Behavior. 2014-10-27. 14(1) : 22-36.
10.1111/gbb.12181 -
Persistence of amygdala gamma oscillations during extinction learning predicts spontaneous fear recovery.
J. Courtin, N. Karalis, C. Gonzalez-Campo, H. Wurtz, C. Herry.
Neurobiology of Learning and Memory. 2014-09-01. 113 : 82-89.
10.1016/j.nlm.2013.09.015 -
Amygdala interneuron subtypes control fear learning through disinhibition
Steffen B. E. Wolff, Jan Gründemann, Philip Tovote, Sabine Krabbe, Gilad A. Jacobson, Christian Müller, Cyril Herry, Ingrid Ehrlich, Rainer W. Friedrich, Johannes J. Letzkus, Andreas Lüthi.
Nature. 2014-05-01. 509(7501) : 453-458.
10.1038/nature13258 -
Frequency of Cocaine Self-Administration Influences Drug Seeking in the Rat: Optogenetic Evidence for a Role of the Prelimbic Cortex
Elena Martín-García, Julien Courtin, Prisca Renault, Jean- François Fiancette, Hélène Wurtz, Amélie Simonnet, Florian Levet, Cyril Herry, Véronique Deroche-Gamonet.
Neuropsychopharmacol. 2014-03-17. 39(10) : 2317-2330.
10.1038/npp.2014.66 -
Long-Range Connectivity Defines Behavioral Specificity of Amygdala Neurons
Verena Senn, Steffen B.E. Wolff, Cyril Herry, François Grenier, Ingrid Ehrlich, Jan Gründemann, Jonathan P. Fadok, Christian Müller, Johannes J. Letzkus, Andreas Lüthi.
Neuron. 2014-01-01. 81(2) : 428-437.
10.1016/j.neuron.2013.11.006 -
Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression
Julien Courtin, Fabrice Chaudun, Robert R. Rozeske, Nikolaos Karalis, Cecilia Gonzalez-Campo, Hélène Wurtz, Azzedine Abdi, Jerome Baufreton, Thomas C. M. Bienvenu, Cyril Herry.
Nature. 2013-11-20. 505(7481) : 92-96.
10.1038/nature12755 -
Medial prefrontal cortex neuronal circuits in fear behavior.
J. Courtin, T.C.M. Bienvenu, E.Ö. Einarsson, C. Herry.
Neuroscience. 2013-06-01. 240 : 219-242.
10.1016/j.neuroscience.2013.03.001 -
A disinhibitory microcircuit for associative fear learning in the auditory cortex
Johannes J. Letzkus, Steffen B. E. Wolff, Elisabeth M. M. Meyer, Philip Tovote, Julien Courtin, Cyril Herry, Andreas Lüthi.
Nature. 2011-12-01. 480(7377) : 331-335.
10.1038/nature10674 -
Nouveaux circuits neuronaux amygdaliens contrôlant le comportement de peur
Stéphane Ciocchi, Andreas Lüthi, Cyril Herry.
Med Sci (Paris). 2011-05-01. 27(5) : 455-457.
10.1051/medsci/2011275003 -
Context-Dependent Encoding of Fear and Extinction Memories in a Large-Scale Network Model of the Basal Amygdala
Ioannis Vlachos, Cyril Herry, Andreas Lüthi, Ad Aertsen, Arvind Kumar.
PLoS Comput Biol. 2011-03-17. 7(3) : e1001104.
10.1371/journal.pcbi.1001104 -
P.2.006 Lesions of the ventral medial prefrontal cortex enhance contextual fear generalisation in C57BL6/J mice
J. Courtin, C. Herry.
European Neuropsychopharmacology. 2011-03-01. 21 : S38-S39.
10.1016/s0924-977x(11)70045-1 -
Encoding of conditioned fear in central amygdala inhibitory circuits
Stephane Ciocchi, Cyril Herry, François Grenier, Steffen B. E. Wolff, Johannes J. Letzkus, Ioannis Vlachos, Ingrid Ehrlich, Rolf Sprengel, Karl Deisseroth, Michael B. Stadler, Christian Müller, Andreas Lüthi.
Nature. 2010-11-11. 468(7321) : 277-282.
10.1038/nature09559 -
Erasing fear memories with extinction training.
G. J. Quirk, D. Pare, R. Richardson, C. Herry, M. H. Monfils, D. Schiller, A. Vicentic.
Journal of Neuroscience. 2010-11-10. 30(45) : 14993-14997.
10.1523/jneurosci.4268-10.2010 -
Impaired fear extinction in mice lacking protease nexin-1
Marita Meins, Cyril Herry, Christian Müller, Stéphane Ciocchi, Eliza Moreno, Andreas Lüthi, Denis Monard.
European Journal of Neuroscience. 2010-05-31. 31(11) : 2033-2042.
10.1111/j.1460-9568.2010.07221.x -
Neuronal circuits of fear extinction
Cyril Herry, Francesco Ferraguti, Nicolas Singewald, Johannes J. Letzkus, Ingrid Ehrlich, Andreas Lüthi.
European Journal of Neuroscience. 2010-02-01. 31(4) : 599-612.
10.1111/j.1460-9568.2010.07101.x -
Amygdalar neuronal circuits implicated in fear conditioning and extinction learning
Cyril Herry.
Neuroscience Research. 2010-01-01. 68 : e19.
10.1016/j.neures.2010.07.318 -
Perineuronal Nets Protect Fear Memories from Erasure
N. Gogolla, P. Caroni, A. Luthi, C. Herry.
Science. 2009-09-03. 325(5945) : 1258-1261.
10.1126/science.1174146 -
Amygdala Inhibitory Circuits and the Control of Fear Memory
Ingrid Ehrlich, Yann Humeau, François Grenier, Stephane Ciocchi, Cyril Herry, Andreas Lüthi.
Neuron. 2009-06-01. 62(6) : 757-771.
10.1016/j.neuron.2009.05.026 -
Switching on and off fear by distinct neuronal circuits
Cyril Herry, Stephane Ciocchi, Verena Senn, Lynda Demmou, Christian Müller, Andreas Lüthi.
Nature. 2008-07-01. 454(7204) : 600-606.
10.1038/nature07166 -
Biphasic ERK1/2 activation in both the hippocampus and amygdala may reveal a system consolidation of contextual fear memory.
P TRIFILIEFF, L CALANDREAU, C HERRY, N MONS, J MICHEAU.
Neurobiology of Learning and Memory. 2007-11-01. 88(4) : 424-434.
10.1016/j.nlm.2007.05.004 -
Processing of temporal unpredictability in human and animal amygdala.
C. Herry, D. R. Bach, F. Esposito, F. Di Salle, W. J. Perrig, K. Scheffler, A. Luthi, E. Seifritz.
Journal of Neuroscience. 2007-05-30. 27(22) : 5958-5966.
10.1523/jneurosci.5218-06.2007 -
Generalization of amygdala LTP and conditioned fear in the absence of presynaptic inhibition
Hamdy Shaban, Yann Humeau, Cyril Herry, Guillaume Cassasus, Ryuichi Shigemoto, Stephane Ciocchi, Samuel Barbieri, Herman van der Putten, Klemens Kaupmann, Bernhard Bettler, Andreas Lüthi.
Nat Neurosci. 2006-07-02. 9(8) : 1028-1035.
10.1038/nn1732 -
Extinction of auditory fear conditioning requires MAPK/ERK activation in the basolateral amygdala
Cyril Herry, Pierre Trifilieff, Jacques Micheau, Andreas Lüthi, Nicole Mons.
European Journal of Neuroscience. 2006-07-01. 24(1) : 261-269.
10.1111/j.1460-9568.2006.04893.x -
Foreground contextual fear memory consolidation requires two independent phases of hippocampal ERK/CREB activation.
P. Trifilieff.
Learning & Memory. 2006-05-01. 13(3) : 349-358.
10.1101/lm.80206 -
Dendritic Spine Heterogeneity Determines Afferent-Specific Hebbian Plasticity in the Amygdala
Yann Humeau, Cyril Herry, Nicola Kemp, Hamdy Shaban, Elodie Fourcaudot, Stephanie Bissière, Andreas Lüthi.
Neuron. 2005-01-01. 45(1) : 119-131.
10.1016/j.neuron.2004.12.019 -
Resistance to extinction is associated with impaired immediate early gene induction in medial prefrontal cortex and amygdala
Cyril Herry, Nicole Mons.
Eur J Neurosci. 2004-08-01. 20(3) : 781-790.
10.1111/j.1460-9568.2004.03542.x -
Behavioral and paired-pulse facilitation analyses of long-lasting depression at excitatory synapses in the medial prefrontal cortex in mice
Cyril Herry, René Garcia.
Behavioural Brain Research. 2003-11-01. 146(1-2) : 89-96.
10.1016/j.bbr.2003.09.017 -
Prefrontal Cortex Long-Term Potentiation, But Not Long-Term Depression, Is Associated with the Maintenance of Extinction of Learned Fear in Mice
Cyril Herry, René Garcia.
J. Neurosci.. 2002-01-15. 22(2) : 577-583.
10.1523/jneurosci.22-02-00577.2002 -
Plasticity in the Mediodorsal Thalamo-Prefrontal Cortical Transmission in Behaving Mice
Cyril Herry, Rose-Marie Vouimba, René Garcia.
Journal of Neurophysiology. 1999-11-01. 82(5) : 2827-2832.
10.1152/jn.1999.82.5.2827