Charlotte Madore-Delpech
Publications
-
Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain.
C. Madore, Q. Leyrolle, L. Morel, M. Rossitto, A. D. Greenhalgh, J. C. Delpech, M. Martinat, C. Bosch-Bouju, J. Bourel, B. Rani, C. Lacabanne, A. Thomazeau, K. E. Hopperton, S. Beccari, A. Sere, A. Aubert, V. De Smedt-Peyrusse, C. Lecours, K. Bisht, L. Fourgeaud, S. Gregoire, L. Bretillon, N. Acar, N. J. Grant, J. Badaut, P. Gressens, A. Sierra, O. Butovsky, M. E. Tremblay, R. P. Bazinet, C. Joffre, A. Nadjar, S. Layé.
Nat Commun. 2020-11-30. 11(1)
10.1038/s41467-020-19861-z -
CSF1R signaling is a regulator of pathogenesis in progressive MS.
Nellwyn Hagan, John L. Kane, Deepak Grover, Lisa Woodworth, Charlotte Madore, Jacqueline Saleh, Jose Sancho, Jinyu Liu, Yi Li, Jonathan Proto, Matija Zelic, Amy Mahan, Michael Kothe, Andrew A. Scholte, Maria Fitzgerald, Barbara Gisevius, Aiden Haghikia, Oleg Butovsky, Dimitry Ofengeim.
Cell Death Dis. 2020-10-01. 11(10)
10.1038/s41419-020-03084-7 -
Correction to: Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy.
Liam Kempthorne, Hyejin Yoon, Charlotte Madore, Scott Smith, Zbigniew K. Wszolek, Rosa Rademakers, Jungsu Kim, Oleg Butovsky, Dennis W. Dickson.
acta neuropathol commun. 2020-06-24. 8(1)
10.1186/s40478-020-00970-1 -
Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy.
Liam Kempthorne, Hyejin Yoon, Charlotte Madore, Scott Smith, Zbigniew K. Wszolek, Rosa Rademakers, Jungsu Kim, Oleg Butovsky, Dennis W. Dickson.
acta neuropathol commun. 2020-05-19. 8(1)
10.1186/s40478-020-00947-0 -
Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities.
Seiko Ikezu, Hana Yeh, Jean-Christophe Delpech, Maya E. Woodbury, Alicia A. Van Enoo, Zhi Ruan, Sudhir Sivakumaran, Yang You, Carl Holland, Teresa Guillamon-Vivancos, Asuka Yoshii-Kitahara, Mina B. Botros, Charlotte Madore, Pin-Hao Chao, Ankita Desani, Solaiappan Manimaran, Srinidhi Venkatesan Kalavai, W. Evan Johnson, Oleg Butovsky, Maria Medalla, Jennifer I. Luebke, Tsuneya Ikezu.
Mol Psychiatry. 2020-02-18.
10.1038/s41380-020-0671-2 -
Microglia, Lifestyle Stress, and Neurodegeneration.
Charlotte Madore, Zhuoran Yin, Jeffrey Leibowitz, Oleg Butovsky.
Immunity. 2020-02-01. 52(2) : 222-240.
10.1016/j.immuni.2019.12.003 -
Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.
Julia K Götzl, Matthias Brendel, Georg Werner, Samira Parhizkar, Laura Sebastian Monasor, Gernot Kleinberger, Alessio‐Vittorio Colombo, Maximilian Deussing, Matias Wagner, Juliane Winkelmann, Janine Diehl‐Schmid, Johannes Levin, Katrin Fellerer, Anika Reifschneider, Sebastian Bultmann, Peter Bartenstein, Axel Rominger, Sabina Tahirovic, Scott T Smith, Charlotte Madore, Oleg Butovsky, Anja Capell, Christian Haass.
EMBO Mol Med. 2019-05-23. 11(6)
10.15252/emmm.201809711 -
Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia.
Kristin Hartmann, Diego Sepulveda-Falla, Indigo V. L. Rose, Charlotte Madore, Christiane Muth, Jakob Matschke, Oleg Butovsky, Shane Liddelow, Markus Glatzel, Susanne Krasemann.
acta neuropathol commun. 2019-05-22. 7(1)
10.1186/s40478-019-0735-1 -
TREMendous 2 Be Social.
Narghes Calcagno, Caroline Baufeld, Charlotte Madore, Oleg Butovsky.
Immunity. 2018-05-01. 48(5) : 842-843.
10.1016/j.immuni.2018.04.034 -
Microglial Phenotypes and Functions in Multiple Sclerosis.
Elaine O’Loughlin, Charlotte Madore, Hans Lassmann, Oleg Butovsky.
Cold Spring Harb Perspect Med. 2018-02-01. 8(2) : a028993.
10.1101/cshperspect.a028993 -
Differential contribution of microglia and monocytes in neurodegenerative diseases.
Caroline Baufeld, Elaine O’Loughlin, Narghes Calcagno, Charlotte Madore, Oleg Butovsky.
J Neural Transm. 2017-10-23. 125(5) : 809-826.
10.1007/s00702-017-1795-7 -
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O’Loughlin, Yang Xu, Zain Fanek, David J. Greco, Scott T. Smith, George Tweet, Zachary Humulock, Tobias Zrzavy, Patricia Conde-Sanroman, Mar Gacias, Zhiping Weng, Hao Chen, Emily Tjon, Fargol Mazaheri, Kristin Hartmann, Asaf Madi, Jason D. Ulrich, Markus Glatzel, Anna Worthmann, Joerg Heeren, Bogdan Budnik, Cynthia Lemere, Tsuneya Ikezu, Frank L. Heppner, Vladimir Litvak, David M. Holtzman, Hans Lassmann, Howard L. Weiner, Jordi Ochando, Christian Haass, Oleg Butovsky.
Immunity. 2017-09-01. 47(3) : 566-581.e9.
10.1016/j.immuni.2017.08.008 -
Microglial confetti party.
Charlotte Madore, Caroline Baufeld, Oleg Butovsky.
Nat Neurosci. 2017-05-25. 20(6) : 762-763.
10.1038/nn.4570 -
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
Fargol Mazaheri, Nicolas Snaidero, Gernot Kleinberger, Charlotte Madore, Anna Daria, Georg Werner, Susanne Krasemann, Anja Capell, Dietrich Trümbach, Wolfgang Wurst, Bettina Brunner, Sebastian Bultmann, Sabina Tahirovic, Martin Kerschensteiner, Thomas Misgeld, Oleg Butovsky, Christian Haass.
EMBO Rep. 2017-05-08. 18(7) : 1186-1198.
10.15252/embr.201743922 -
The brain parenchyma has a type I interferon response that can limit virus spread.
Eugene Drokhlyansky, Didem Göz Aytürk, Timothy K. Soh, Ryan Chrenek, Elaine O’Loughlin, Charlotte Madore, Oleg Butovsky, Constance L. Cepko.
Proc Natl Acad Sci USA. 2016-12-15. 114(1) : E95-E104.
10.1073/pnas.1618157114 -
Activation of microglia by retroviral infection correlates with transient clearance of prions from the brain but does not change incubation time.
Christiane Muth, Katharina Schröck, Charlotte Madore, Kristin Hartmann, Zain Fanek, Oleg Butovsky, Markus Glatzel, Susanne Krasemann.
Brain Pathology. 2016-11-21. 27(5) : 590-602.
10.1111/bpa.12441