Neuromodulation and neuroprosthetics


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Over the past few years, our team has initiated a multifaceted research program that aims at developing new neuromodulation strategies and neuroprosthetic systems for improving motor and cognitive functions in neurological disorders. We believe that this field requires a synergistic approach between neuromodulation / neuroprosthetics and computational neuroscience, two aspects led collaboratively by Dr. Fabien Wagner (CNRS) and Dr. Amélie Aussel (Inria). We are currently conducting the following projects:

  • Biophysical models of the neural circuits that produce cognition, especially memory and attention, and how they are affected by neurostimulation.
  • Personalized physical models of the head and brain based on neuroimaging (CT, anatomical and diffusion MRI) to determine the distribution of the electric field induced by various neurostimulation methods and the affected brain structures.
  • Invasive neurostimulation in non-human primates for improving memory using novel intracranial brain implants that target large-scale brain networks identified by submillimeter MRI protocols. The MEMOPROSTHETICS project is funded by an ERC starting grant led by Dr. Fabien Wagner (2022-2027).
  • Non-invasive brain and spinal cord stimulation for improving motor and cognitive functions after spinal cord injury and stroke. This project is funded by a fellowship from the “Fondation pour la Recherche Médicale” (FRM) attributed to Dr. Nabila Brihmat (2024-2027), and is performed in collaboration with Dr. Hélène Cassoudesalle from the Physical Medicine and Rehabilitation department at the CHU-BDX.
  • Multimodal digital therapeutics for improving cognition in neurovascular disorders using EEG biomarker identification, high-definition transcranial alternating current stimulation (tACS), and cognitive training. This effort is part of the new Vascular Brain Health Institute ( and involves a collaboration with Pr. Stéphanie Debette (CHU-BDX), Dr. Fabien Lotte (Inria) and Dr. Hélène Sauzéon (Inria).

Selected publications

Team leader
Fabien Wagner

Amélie Aussel

Team member(s)

Chercheurs, Praticiens hospitaliers...

Ingénieur(e)s, technicien(ne)s


Nabila Brihmat


Nikolaos Vardalakis
Adrien Boissenin
Maeva Andriantsoamberomanga

Neuropsychologist(s) and speech therapist(s)

Ingénieur(s) hospitalier(s) et ARC