Jan Pieter Konsman

Scientific articles

• Review of: “LC, POTS, and ME/CFS: Lifting the Fog”
  Jan Pieter Konsman.
  Qeios. 2023-04-15.
  10.32388/ZIGIWP
• Philosophical Perspectives on Neuroendocrine–Immune Interactions: The Building Block Model and Complementary Neuro-Endocrine-Immune-Microbiota Systems Approaches
  Gregor P. Greslehner, Federico Boem, Lynn Chiu, Jan Pieter Konsman.
  Masterclass in Neuroendocrinology. 2023-01-01. : 31-61.
  10.1007/978-3-031-21358-8_2
• Cytokines in the Brain and Neuroinflammation: We Didn’t Starve the Fire!
  Jan Pieter Konsman.
  Pharmaceuticals. 2022-01-25. 15(2) : 140.
  10.3390/ph15020140
• Brain Perivascular Macrophages Do Not Mediate Interleukin-1-Induced Sickness Behavior in Rats
  Léa Chaskiel, Robert Dantzer, Jan Konsman.
  Pharmaceuticals. 2021-10-11. 14(10) : 1030.
  10.3390/ph14101030
• Magnetic resonance imaging under isoflurane anesthesia alters cortical cyclooxygenase‐2 expression and glial cell morphology during sepsis‐associated neurological dysfunction in rats
  Ibtihel Dhaya, Marion Griton, Jan Pieter Konsman.
  Animal Models and Experimental Medicine. 2021-05-03.
  10.1002/ame2.12167
• Inflammation and Depression: A Nervous Plea for Psychiatry to Not Become Immune to Interpretation
  Jan Konsman.
  Pharmaceuticals. 2019-02-14. 12(1) : 29.
  10.3390/ph12010029
• Causal clarity and deeper dimensions in microbiota-gut-brain research
  Katarzyna B. Hooks, Jan Pieter Konsman, Maureen A. O'Malley.
  Behav Brain Sci. 2019-01-01. 42
  10.1017/S0140525X19000050
• Microbiota-gut-brain research: A critical analysis
  Katarzyna B. Hooks, Jan Pieter Konsman, Maureen A. O'Malley.
  Behav Brain Sci. 2018-09-12. 42
  10.1017/S0140525X18002133
• Neural pathways involved in infection-induced inflammation: recent insights and clinical implications
  Marion Griton, Jan Pieter Konsman.
  Clin Auton Res. 2018-03-14. 28(3) : 289-299.
  10.1007/s10286-018-0518-y
• Bacterial lipopolysaccharide-induced systemic inflammation alters perfusion of white matter-rich regions without altering flow in brain-irrigating arteries: Relationship to blood-brain barrier breakdown?
  Ibtihel Dhaya, Marion Griton, Gérard Raffard, Mohamed Amri, Bassem Hiba, Jan Pieter Konsman.
  Journal of Neuroimmunology. 2018-01-01. 314 : 67-80.
  10.1016/j.jneuroim.2017.11.009
• Vascular impairment as a pathological mechanism underlying long-lasting cognitive dysfunction after pediatric traumatic brain injury.
  Aleksandra Ichkova, Beatriz Rodriguez-Grande, Claire Bar, Frederic Villega, Jan Pieter Konsman, Jerome Badaut.
  Neurochemistry International. 2017-12-01. 111 : 93-102.
  10.1016/j.neuint.2017.03.022
• Gas Diffusion in the CNS.
  Beatriz Rodriguez-Grande, Jan-Pieter Konsman.
  J Neuro Res. 2017-05-15. 96(2) : 207-218.
  10.1002/jnr.24077
• Circulating bacterial lipopolysaccharide-induced inflammation reduces flow in brain-irrigating arteries independently from cerebrovascular prostaglandin production.
  Frédéric Villéga, Jean-Christophe Delpech, Marion Griton, Caroline André, Jean-Michel Franconi, Sylvain Miraux, Jan Pieter Konsman.
  Neuroscience. 2017-03-01. 346 : 160-172.
  10.1016/j.neuroscience.2017.01.018
• Mechanisms of the behavioural effects of cytokines.
  Robert Dantzer, Arnaud Aubert, Rose-Marie Bluthé, Gilles Gheusi, Sandrine Cremona, Sophie Layé, Jan-Pieter Konsman, Patricia Parnet, Keith W. Kelley.
  Adv Exp Med Biol.. 1999. 461 : 83-105.
  
• Neural pathways from the immune system to the brain. International Workshop organized under the auspices of the BIO-MED I Concerted Action “Cytokines in the brain.” Marseille, 7 December 1996.
  Konsman JP, Cartmell T..
  Eur Cytokine Netw.. 1997-06. 8(2) : 221-3.
  
• Hypothalamic, metabolic, and behavioral responses to pharmacological inhibition of CNS melanocortin signaling in rats.
  Adage T, Scheurink AJ, de Boer SF, de Vries K, Konsman JP, Kuipers F, Adan RA, Baskin DG, Schwartz MW, van Dijk G..
  J Neurosci.. 2001 May 15. 21(10) : 3639-45.
  
• Neurobiology of interleukin-1 receptors: getting the message.
  Konsman JP, Blond D, Vigues S..
  Eur Cytokine Netw.. 2000-12-01. 11(4) : 699-702.
  
• Brainstem metabotropic glutamate receptors reduce food intake and activate dorsal pontine and medullar structures after peripheral bacterial lipopolysaccharide administration.
  Léa Chaskiel, Flora Paul, Rüdiger Gerstberger, Thomas Hübschle, Jan Pieter Konsman.
  Neuropharmacology. 2016-08-01. 107 : 146-159.
  10.1016/j.neuropharm.2016.03.030
• Lipopolysaccharide increases degradation of central monoamines: an in vivo microdialysis study in the nucleus accumbens and medial prefrontal cortex of mice.
  Floor van Heesch, Jolanda Prins, Jan Pieter Konsman, Gerdien A.H. Korte-Bouws, Koen G.C. Westphal, Joanna Rybka, Berend Olivier, Aletta D. Kraneveld, S. Mechiel Korte.
  European Journal of Pharmacology. 2014-02-01. 725 : 55-63.
  10.1016/j.ejphar.2014.01.014
• Inhibitory activity of plant stilbenoids against nitric oxide production by lipopolysaccharide-activated microglia.
  Merian Nassra, Stéphanie Krisa, Yorgos Papastamoulis, Gilbert Kapche, Jonathan Bisson, Caroline André, Jan-Pieter Konsman, Jean-Marie Schmitter, Jean-Michel Mérillon, Pierre Waffo-Téguo.
  Planta Med. 2013-06-27. 79(11) : 966-970.
  10.1055/s-0032-1328651
• Does television reflect the evolution of scientific knowledge? The case of attention deficit hyperactivity disorder coverage on French television.
  Mélanie Bourdaa, Jan Pieter Konsman, Claire Sécail, Tommaso Venturini, Isabelle Veyrat-Masson, Francois Gonon.
  Public Underst Sci. 2013-06-04. 24(2) : 200-209.
  10.1177/0963662513484842
• Food restriction-induced hyperactivity: addiction or adaptation to famine?
  Martine Duclos, Amel Ouerdani, Pierre Mormède, Jan Pieter Konsman.
  Psychoneuroendocrinology. 2013-06-01. 38(6) : 884-897.
  10.1016/j.psyneuen.2012.09.012
• Lipopolysaccharide-induced anhedonia is abolished in male serotonin transporter knockout rats: an intracranial self-stimulation study.
  Floor van Heesch, Jolanda Prins, Jan Pieter Konsman, Koen G.C. Westphal, Berend Olivier, Aletta D. Kraneveld, S. Mechiel Korte.
  Brain, Behavior, and Immunity. 2013-03-01. 29 : 98-103.
  10.1016/j.bbi.2012.12.013
• Why most biomedical findings echoed by newspapers turn out to be false: the case of attention deficit hyperactivity disorder.
  François Gonon, Jan-Pieter Konsman, David Cohen, Thomas Boraud.
  PLoS ONE. 2012-09-12. 7(9) : e44275.
  10.1371/journal.pone.0044275
• The calm mouse: an animal model of stress reduction.
  Blake Gurfein, Andrew Stamm.
  Mol. Med.. 2012-01-01. 18(4) : 1.
  10.2119/molmed.2012.00053
• Hormonal, hypothalamic and striatal responses to reduced body weight gain are attenuated in anorectic rats bearing small tumors.
  Line Pourtau, Susan Leemburg, Pascale Roux, Thierry Leste-Lasserre, Patricia Costaglioli, Bertrand Garbay, Guillaume Drutel, Jan Pieter Konsman.
  Brain, Behavior, and Immunity. 2011-05-01. 25(4) : 777-786.
  10.1016/j.bbi.2011.02.004
• In vivo MR tracking of therapeutic microglia to a human glioma model.
  Emeline J. Ribot, Sylvain Miraux, Jan P. Konsman, Véronique Bouchaud, Line Pourtau, Marie-Hélène Delville, Jean-Michel Franconi, Eric Thiaudière, Pierre J. Voisin.
  NMR Biomed.. 2011-03-08. 24(10) : 1361-1368.
  10.1002/nbm.1699
• Brain cyclooxygenase-2 mediates interleukin-1-induced cellular activation in preoptic and arcuate hypothalamus, but not sickness symptoms.
  Agnès Nadjar, Julie Sauvant, Chantal Combe, Patricia Parnet, Jan Pieter Konsman.
  Neurobiology of Disease. 2010-09-01. 39(3) : 393-401.
  10.1016/j.nbd.2010.05.005
• Short-term effect of erythropoietin on brain lesions and aquaporin-4 expression in a hypoxic-ischemic neonatal rat model assessed by magnetic resonance diffusion weighted imaging and immunohistochemistry.
  Olivier Brissaud, Frédéric Villega, Jan Pieter Konsman, Stéphane Sanchez, Gérard Raffard, Jean-Michel Franconi, Jean-François Chateil, Anne-Karine Bouzier-Sore.
  Pediatr Res. 2010-08-01. 68(2) : 123-127.
  10.1203/pdr.0b013e3181e67d02
• Inhibition of hippocampal cell proliferation by methotrexate in rats is not potentiated by the presence of a tumor.
  Riejanne Seigers, Line Pourtau, Sanne B. Schagen, Frits S.A.M. van Dam, Jaap M. Koolhaas, Jan Pieter Konsman, Bauke Buwalda.
  Brain Research Bulletin. 2010-03-01. 81(4-5) : 472-476.
  10.1016/j.brainresbull.2009.10.006
• Plasma transcortin influences endocrine and behavioral stress responses in mice.
  Elodie M. Richard, Jean-Christophe Helbling, Claudine Tridon, Aline Desmedt, Amandine M. Minni, Martine Cador, Line Pourtau, Jan-Pieter Konsman, Pierre Mormède, Marie-Pierre Moisan.
  Endocrinology. 2010-02-01. 151(2) : 649-659.
  10.1210/en.2009-0862
• Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide.
  J. P. Konsman, J. Veeneman, C. Combe, S. Poole, G. N. Luheshi, R. Dantzer.
  European Journal of Neuroscience. 2008-12-01. 28(12) : 2499-2510.
  10.1111/j.1460-9568.2008.06549.x
• Systemic immune challenge activates an intrinsically regulated local inflammatory circuit in the adrenal gland.
  Linda Engström, Khadijah Rosén, Anna Angel, Anna Fyrberg, Ludmila Mackerlova, Jan Pieter Konsman, David Engblom, Anders Blomqvist.
  Endocrinology. 2008-04-01. 149(4) : 1436-1450.
  10.1210/en.2007-1456
• (Peri)vascular production and action of pro-inflammatory cytokines in brain pathology.
  Jan P. Konsman, Benjamin Drukarch, Anne-Marie Van Dam.
  Clin. Sci.. 2007-01-01. 112(1) : 1-25.
  10.1042/cs20060043
• Excitement over the chemistry of immune-nervous system relationships.
  Jan Pieter Konsman.
  Brain, Behavior, and Immunity. 2006-05-01. 20(3) : 231-232.
  10.1016/j.bbi.2005.12.001
• Forebrain patterns of c-Fos and FosB induction during cancer-associated anorexia-cachexia in rat.
  Jan Pieter Konsman, Anders Blomqvist.
  European Journal of Neuroscience. 2005-05-01. 21(10) : 2752-2766.
  10.1111/j.1460-9568.2005.04102.x
• Fever and hypothermia in systemic inflammation: recent discoveries and revisions.
  Andrej, A. Romanovsky.
  Front Biosci. 2005-01-01. 10(1-3) : 2193.
  10.2741/1690
• Rat brain vascular distribution of interleukin-1 type-1 receptor immunoreactivity: relationship to patterns of inducible cyclooxygenase expression by peripheral inflammatory stimuli.
  Jan Pieter Konsman, Stephan Vigues, Ludmila Mackerlova, Adrian Bristow, Anders Blomqvist.
  J. Comp. Neurol.. 2004-01-01. 472(1) : 113-129.
  10.1002/cne.20052
• Chronic treatment with the antidepressant tianeptine attenuates lipopolysaccharide-induced Fos expression in the rat paraventricular nucleus and HPA axis activation.
  Nathalie Castanon, Jan-Pieter Konsman, Chantal Médina, Nathalie Chauvet, Robert Dantzer.
  Psychoneuroendocrinology. 2003-01-01. 28(1) : 19-34.
  10.1016/s0306-4530(02)00005-7
• Chronic treatment with the antidepressant tianeptine attenuates lipopolysaccharide-induced Fos expression in the rat paraventricular nucleus and HPA axis activation.
  Nathalie Castanon, Jan-Pieter Konsman, Chantal Médina, Nathalie Chauvet, Robert Dantzer.
  Psychoneuroendocrinology. 2003-01-01. 28(1) : 19-34.
  10.1016/s0306-4530(02)00005-7
• Cytokines and the ageing brain.
  Colm Cunningham, Jan-Pieter Konsman, Tammy Cartmell.
  Trends in Neurosciences. 2002-11-01. 25(11) : 546-547.
  10.1016/s0166-2236(02)02265-8
• Cytokine-induced sickness behaviour: mechanisms and implications.
  Jan Pieter Konsman, Patricia Parnet, Robert Dantzer.
  Trends in Neurosciences. 2002-03-01. 25(3) : 154-159.
  10.1016/s0166-2236(00)02088-9
• How the immune and nervous systems interact during disease-associated anorexia.
  Jan Pieter Konsman, Robert Dantzer.
  Nutrition. 2001-07-01. 17(7-8) : 664-668.
  10.1016/s0899-9007(01)00602-5
• Vagotomy attenuates the behavioural but not the pyrogenic effects of interleukin-1 in rats.
  Giamal N Luheshi, Rose-Marie Bluthé, David Rushforth, Nicholas Mulcahy, Jan-Pieter Konsman, Michael Goldbach, Robert Dantzer.
  Autonomic Neuroscience. 2000-12-01. 85(1-3) : 127-132.
  10.1016/s1566-0702(00)00231-9
• Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent?
  Robert Dantzer, Jan-Pieter Konsman, Rose-Marie Bluthé, Keith W Kelley.
  Autonomic Neuroscience. 2000-12-01. 85(1-3) : 60-65.
  10.1016/s1566-0702(00)00220-4
• The vagus nerve mediates behavioural depression, but not fever, in response to peripheral immune signals; a functional anatomical analysis.
  Jan Pieter Konsman, Giamal N. Luheshi, Rose-Marie Bluthé, Robert Dantzer.
  European Journal of Neuroscience. 2000-12-01. 12(12) : 4434-4446.
  10.1046/j.0953-816x.2000.01319.x
• Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent?
  Robert Dantzer, Jan-Pieter Konsman, Rose-Marie Bluthé, Keith W Kelley.
  Autonomic Neuroscience. 2000-12-01. 85(1-3) : 60-65.
  10.1016/s1566-0702(00)00220-4
• Cytokine signals propagate through the brain.
  L Vitkovic, J P Konsman, J Bockaert, R Dantzer, V Homburger, C Jacque.
  Mol Psychiatry. 2000-11-01. 5(6) : 604-615.
  10.1038/sj.mp.4000813
• Diffusion and action of intracerebroventricularly injected interleukin-1 in the CNS.
  J.P Konsman, V Tridon, R Dantzer.
  Neuroscience. 2000-11-01. 101(4) : 957-967.
  10.1016/s0306-4522(00)00403-6
• Diffusion and action of intracerebroventricularly injected interleukin-1 in the CNS.
  J.P Konsman, V Tridon, R Dantzer.
  Neuroscience. 2000-11-01. 101(4) : 957-967.
  10.1016/s0306-4522(00)00403-6
• Temporal and spatial relationships between lipopolysaccharide-induced expression of Fos, interleukin-1beta and inducible nitric oxide synthase in rat brain.
  J.P. Konsman, K. Kelley, R. Dantzer.
  Neuroscience. 1999-03-01. 89(2) : 535-548.
  10.1016/s0306-4522(98)00368-6
• Temporal and spatial relationships between lipopolysaccharide-induced expression of Fos, interleukin-1beta and inducible nitric oxide synthase in rat brain.
  J.P. Konsman, K. Kelley, R. Dantzer.
  Neuroscience. 1999-03-01. 89(2) : 535-548.
  10.1016/s0306-4522(98)00368-6
• Differential effects of CRH infusion into the central nucleus of the amygdala in the Roman high-avoidance and low-avoidance rats.
  A. Wiersma, J.P. Konsman, S. Knollema, B. Bohus, J.M. Koolhaas.
  Psychoneuroendocrinology. 1998-04-01. 23(3) : 261-274.
  10.1016/s0306-4530(97)00098-x
• Differential effects of CRH infusion into the central nucleus of the amygdala in the Roman high-avoidance and low-avoidance rats.
  A. Wiersma, J.P. Konsman, S. Knollema, B. Bohus, J.M. Koolhaas.
  Psychoneuroendocrinology. 1998-04-01. 23(3) : 261-274.
  10.1016/s0306-4530(97)00098-x
• Corticotropin-releasing hormone modulation of a conditioned stress response in the central amygdala of Roman high (RHA/Verh)-avoidance and low (RLA/Verh)-avoidance rats.
  A. Wiersma, S. Knollema, J. P. Konsman, B. Bohus, J. M. Koolhaas.
  Behavior Genetics. 1997-01-01. 27(6) : 547-555.
  10.1023/a:1021457015482
• Corticotropin-releasing hormone modulation of a conditioned stress response in the central amygdala of Roman high (RHA/Verh)-avoidance and low (RLA/Verh)-avoidance rats.
  A. Wiersma, S. Knollema, J. P. Konsman, B. Bohus, J. M. Koolhaas.
  Behavior Genetics. 1997-01-01. 27(6) : 547-555.
  10.1023/a:1021457015482