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Société des Neurosciences’s 2020 highlights

To select these “2020 Highlights”, the members of the Board of Directors of the Society for Neuroscience have selected some of the most outstanding publications in their discipline. The magnificent discoveries presented here testify to the vitality of French Neuroscience and to the reality of the advancement of knowledge in all branches of Neuroscience, thanks to researchers in France. Many other articles would have deserved to be in this sample!

Among the 18 highlights, 5 are from our teams!

Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice. Bertin E, Deluc T, Pilch KS, Audrey Martinez A, Pougnet JT, Doudnikoff E, Allain AE, Bergmann P, Russeau M, Toulmé E, Bezard E, Koch-Nolte F, Séguéla P, Lévi S, Bontempi B, Georges F, Bertrand S, Nicole O and Boué-Grabot E.
(2020) Molecular Psychiatry DOI : 10.1038/s41380-019-0641-8

Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates. Bourdenx M, Nioche A, Dovero S, Arotcarena ML, Camus S, Porras G, Thiolat ML, Rougier NP, Prigent A, Aubert P, Bohic S, Sandt C, Laferrière F, Doudnikoff E, Kruse N, Mollenhauer B, Novello S, Morari M, Leste-Lasserre T, Damas IT, Goillandeau M, Perier C, Estrada C, Garcia-Carrillo N, Recasens A, Vaikath NN, El-Agnaf OMA, Herrero MT, Derkinderen P, Vila M, Obeso JA, Dehay B, Bezard E.
Sci Adv. 2020 May 13;6(20):eaaz9165.

Causal Link between n-3 Polyunsaturated Fatty Acid Deficiency and Motivation Deficits. Ducrocq, F., Walle, R., Contini, A., Oummadi, A., Caraballo, B., van der Veldt, S., Boyer, M.-L., Aby, F., Tolentino-Cortez, T., Helbling, J.-C., Martine, L., Grégoire, S., Cabaret, S., Vancassel, S., Layé, S., Kang, J.X., Fioramonti, X., Berdeaux, O., Barreda-Gómez, G., Masson, E., Ferreira, G., Ma, D.W.L., Bosch-Bouju, C., De Smedt-Peyrusse, V. and Trifilieff, P.
Cell Metab. (2020). 31, 755-772.e7. https://doi.org/10.1016/j.cmet.2020.02.012.

Glucose metabolism links astroglial mitochondria to cannabinoid effects. Jimenez-Blasco D, Busquets-Garcia A, Hebert-Chatelain E, Serrat R, Vicente-Gutierrez C, Ioannidou C, Gómez-Sotres P, Lopez-Fabuel I, Resch-Beusher M, Resel E, Arnouil D, Saraswat D, Varilh M, Cannich A, Julio-Kalajzic F, Bonilla-Del Río I, Almeida A, Puente N, Achicallende S, Lopez-Rodriguez ML, Jollé C, Déglon N, Pellerin L, Josephine C, Bonvento G, Panatier A, Lutz B, Piazza PV, Guzmán M, Bellocchio L, Bouzier-Sore AK, Grandes P, Bolaños JP, Marsicano G.
Nature. 2020 Jul;583(7817):603-608. doi: 10.1038/s41586-020-2470-y. Epub 2020 Jul 8.

Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease.
Le Douce J*, Maugard M*, Veran J*, Matos M*, Jégo P, Vigneron PA, Faivre E, Toussay X, Vandenberghe M, Balbastre Y, Piquet J, Guiot E, Tran NT, Taverna M, Marinesco S, Koyanagi A, Furuya S, Gaudin-Guérif M, Goutal S, Ghettas A, Pruvost A, Bemelmans AP, Gaillard MC, Cambon K, Stimmer L, Sazdovitch V, Duyckaerts C, Knott G, Hérard AS, Delzescaux T, Hantraye P, Brouillet E, Cauli B, Oliet SHR, Panatier A#, Bonvento G#. Cell Metab. 2020 Mar 3;31(3):503-517.e8. doi: 10.1016/j.cmet.2020.02.004.

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Selection 2021

For the 2021 selection, all members of the Society for Neuroscience are invited to send the articles they have written or read with the mention “fait marquant, pour sélection ultérieure” to

 

05/02/21