Venue: Centre Broca
Eric Yttri
Carnegie Mellon University, USA
Title
Corticostriatal dynamics underlying the control of behavior and learning
Abstract
Neural circuits across the brain give rise to the performance and improvement of behavior decisions. Our recent work reveals the computational contributions of different cell types across the corticostriatal circuit to behavior. Across trained and untrained task contexts, a functional blueprint has emerged in which motor cortex encodes what actions to perform, while striatum determines how to perform them. Through dopamine-dependent plasticity mechanisms, striatum also performs policy-based association across a range of behaviorally-relevant representations, from movement kinematics to information integration. Finally, as a product of our attempts to understand these neural dynamics, we have identified the neural hallmarks of hesitation and freezing of gait, which often manifest as a result of neurological disorders.
Invited by Nicolas Mallet