SnapShot: Receptor dynamics at plastic synapses

Matthias Kneussel, Antoine Triller, Daniel Choquet
Cell. 2014-06-01; 157(7): 1738-1738.e1
DOI: 10.1016/j.cell.2014.06.002

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Kneussel M(1), Triller A(2), Choquet D(3).

Author information:
(1)University Medical Center Hamburg Eppendorf, Falkenried 94, 20251 Hamburg,
(2)Ecole Normale Superieure, Institute of Biologie (IBENS) CNRS UMR 8197, Inserm
1024, 46 rue d’Ulm, Paris 75005, France.
(3)Interdisciplinary Institute for Neurosciences, CNRS, Bordeaux University, UMR
5297, 146 rue Leo Saignat, 33077 Bordeaux, France.

The dynamic synapse is represented by the constant mobility and exchange of
components at both the cell surface and at intracellular sites. This includes
thermally powered Brownian diffusion movement, followed by reversible trapping
through receptor-scaffold interactions and active transport of cargo vesicles
through cytoskeletal motors.

Copyright © 2014 Elsevier Inc. All rights reserved.


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