SnapShot: receptor dynamics at plastic synapses

Matthias Kneussel; Antoine Triller; Daniel Choquet

doi:10.1016/j.cell.2014.06.002

SnapShot: receptor dynamics at plastic synapses

Cell. 2014 Jun 19;157(7):1738-1738.e1. doi: 10.1016/j.cell.2014.06.002.

Authors

Matthias Kneussel¹, Antoine Triller², Daniel Choquet³

Affiliations

¹ University Medical Center Hamburg Eppendorf, Falkenried 94, 20251 Hamburg, Germany.
² Ecole Normale Superieure, Institute of Biologie (IBENS) CNRS UMR 8197, Inserm 1024, 46 rue d'Ulm, Paris 75005, France.
³ Interdisciplinary Institute for Neurosciences, CNRS, Bordeaux University, UMR 5297, 146 rue Leo Saignat, 33077 Bordeaux, France.

PMID: 24949980
DOI: 10.1016/j.cell.2014.06.002

Abstract

The dynamic synapse is represented by the constant mobility and exchange of components at both the cell surface and at intracellular sites. This includes thermally powered Brownian diffusion movement, followed by reversible trapping through receptor-scaffold interactions and active transport of cargo vesicles through cytoskeletal motors.

MeSH terms

Animals
Humans
Neuronal Plasticity*
Neurotransmitter Agents / metabolism
Receptors, Neurotransmitter / metabolism
Synapses / physiology*

Substances

Neurotransmitter Agents
Receptors, Neurotransmitter