Brigitt Raux
Post-doctorante
/ Contact
www.orcid.org/0000-0002-2194-0259
Publications
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Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach.
Laurent Hoffer, Yuliia V. Voitovich, Brigitt Raux, Kendall Carrasco, Christophe Muller, Aleksey Y. Fedorov, Carine Derviaux, Agnès Amouric, Stéphane Betzi, Dragos Horvath, Alexandre Varnek, Yves Collette, Sébastien Combes, Philippe Roche, Xavier Morelli.
J. Med. Chem.. 2018-06-08. 61(13) : 5719-5732.
10.1021/acs.jmedchem.8b00653 -
Slowing down fat digestion and absorption by oxadiazolone inhibitor targeting selectively gastric lipolysis
Vanessa Point, Anais Bénarouche, Julie Zarrillo, Alexandre Guy, Romain Magnez, Laurence Fonseca, Brigitt Raux, Julien Leclaire, Gérard Buono, Frédéric Fotiadu, Thierry Durand, Frédéric Carrière, Carole Vaysse, Leslie Couëdelo, Jean-François Cavalier.
European Journal of Medicinal Chemistry. 2016-11-10. 123 : 834-848.
10.1016/j.ejmech.2016.08.009 -
Protein-Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery
Sabine Milhas, Brigitt Raux, Stéphane Betzi, Carine Derviaux, Philippe Roche, Audrey Restouin, Marie-Jeanne Basse, Etienne Rebuffet, Adrien Lugari, Marion Badol, Rudra Kashyap, Jean-Claude Lissitzky, Cécilia Eydoux, Véronique Hamon, Marie-Edith Gourdel, Sébastien Combes, Pascale Zimmermann, Michel Aurrand-Lions, Thomas Roux, Catherine Rogers, Susanne Müller, Stefan Knapp, Eric Trinquet, Yves Collette, Jean-Claude Guillemot, and Xavier Morelli.
ACS Chem. Biol.. May 24, 2016. 11(8) : 2140-2148.
10.1021/acschembio.6b00286 -
Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins
Brigitt Raux, Yuliia Voitovich, Carine Derviaux, Adrien Lugari, Etienne Rebuffet, Sabine Milhas, Stéphane Priet, Thomas Roux Eric Trinquet Jean-Claude Guillemot, Stefan Knapp, Jean-Michel Brunel, Alexey Yu. Fedorov, Yves Collette, Philippe Roche, Stéphane Betzi, Sébastien Combes, and Xavier Morelli.
J Med Chem. . 59(4) : 1634-41.
10.1021/acs.jmedchem.5b01708 -
Supported inhibitor for fishing lipases in complex biological media and mass spectrometry identification
Vincent Delorme, Brigitt Raux, Rémy Puppo, Julien Leclaire, Jean-François Cavaliera, Sylvain Marc, Pavan-Kumar Kamarajugadd, Gérard Buono, Frédéric Fotiadu, Stéphane Canaan, Frédéric Carrière.
Biochimie. 2014 Dec. 107 : 124-134.
10.1016/j.biochi.2014.07.015