Venue: Centre Broca Nouvelle-Aquitaine
Nako Nakatsuka
Laboratory of Biosensors and Bioelectronics (LBB)
ETH Zürich
Invited by Clémentine Bosch Bouju (NutriNeuro)
Title
Aptamer-based biosensors for in vivo neurotransmitter monitoring
Key publications
Weaver S, Mohammadi MH, Nakatsuka N. Aptamer-functionalized capacitive biosensors. Biosens Bioelectron. 2023 Mar 15;224:115014. doi: 10.1016/j.bios.2022.115014. Epub 2022 Dec 23. PMID: 36628826.
Zhao C, Cheung KM, Huang IW, Yang H, Nakatsuka N, Liu W, Cao Y, Man T, Weiss PS, Monbouquette HG, Andrews AM. Implantable aptamer-field-effect transistor neuroprobes for in vivo neurotransmitter monitoring. Sci Adv. 2021 Nov 26;7(48):eabj7422. doi: 10.1126/sciadv.abj7422. Epub 2021 Nov 24. PMID: 34818033; PMCID: PMC8612678.
Moraldo C, Vuille-Dit-Bille E, Shkodra B, Kloter T, Nakatsuka N. Aptamer-modified biosensors to visualize neurotransmitter flux. J Neurosci Methods. 2022 Jan 1;365:109386. doi: 10.1016/j.jneumeth.2021.109386. Epub 2021 Oct 13. PMID: 34653500.
Nakatsuka N, Heard KJ, Faillétaz A, Momotenko D, Vörös J, Gage FH, Vadodaria Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes. Mol Psychiatry. 2021 Jul;26(7):2753-2763. doi: 10.1038/s41380-021-01066-5. Epub 2021 Mar 25. PMID: 33767349.
Nakatsuka N, Yang KA, Abendroth JM, Cheung KM, Xu X, Yang H, Zhao C, Zhu B, Rim YS, Yang Y, Weiss PS, Stojanović MN, Andrews AM. Aptamer-field-effect transistors overcome Debye length limitations for small-molecule sensing. Science. 2018 Oct 19;362(6412):319-324. doi: 10.1126/science.aao6750. Epub 2018 Sep 6. PMID: 30190311; PMCID: PMC6663484.