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Cajal lectures: Ageing cognition

lundi 20 septembre - samedi 9 octobre

The lectures during the Cajal course are open to every member of Bordeaux Neurocampus.

Venue: CGFB

September 20 – 2:00pm
Luisa Lopes (iMM Lisboa, Portugal)
Towards assessing human synaptic aging – new models

September 21 – 9:00am (remotely)
Cheryl Grady (University of Toronto, Canada)
Using neuroimaging to examine between-person and within-person variability in cognition across the adult lifespan

September 21 – 11:00am
Nora Abrous (Bordeaux Neurocampus, France)
Role of hippocampus neurogensis incognitive aging

September 22 – 9:00am
Carol Barnes (University of Arizona, USA)
Region-selective hippocampal contributions to altered cognition in aging

September 22 – 11:00am (remotely)
Maria Llorens-Martin (Universidad Autonoma Madrid, Spain)
Human adult hippocampal neurogenesis during physiological and pathological aging

September 24 – 9:00am
Laure Rondi-Reig (Sorbonne University, France)
Studying Memory systems using navigation behavior

September 24 – 11:00
Aline Marighetto (Bordeaux Neurocampus, France)
Age-related decline of declarative memory: from temporal binding process to synaptic trafficking of hippocampal NMDA receptors

September 27 – 5:00pm (remotely)
Yaakov Stern (Columbia University, USA)
The neural basis of cognitive reserve

September 30 – 11:00am (remotely)
Adam Antebi (Max Plank Institute, Germany)
Convergent mechanisms of longevity

October 4 – 9:00am
Luc Buée (University of Lille, France)
Alzheimer’s disease: The amyloid cascade hypothesis from the tau side

October 4 – 11:00am
Lars Nyberg (Umea University, Sweden)
Studies of “brain reserve”, “cognitive reserve”, and “brain maintenance” – and some thoughts on “resilience”

October 5 – 9:00am (remotely)
Hélène Amieva (Bordeaux population health center, France)
Trajectories of cognitive ageing: lessons from population-based epidemiologic studies

October 5 – 11:00am
Gwenaëlle Catheline (Bordeaux Neurocampus, France)
Inter-individual variability in brain changes during aging : multimodal MRI-based studies in population based-cohorts


About the Cajal course

Venue: Bordeaux School of Neuroscience

The normal aging process is associated with reduced performance on cognitive tasks that require one to quickly process or transform information to make a decision, including measures of speed of processing, executive cognitive function, working and relational memories. Structural and functional alterations in the brain correlate with these age-related cognitive changes, such as loss of synapses, and dysfunction of neuronal networks. It is crucial to develop new approaches that consider the whole neuroanatomical, endocrine, immunological, vascular and cellular changes impacting on cognition.

This 3-week course will cover the fundamentals of cognitive aging -including inter-individual differences, cognitive and brain reserve and risk factors- and highlight the newest functional imaging methods to study human brain function. The Faculty will share the state-of-the-art molecular, optical, computational, electrophysiological, behavioural and epidemiological approaches available for studying the aging brain in diverse model systems. The Students will learn the potential and limitations of these methods, through practical experience in a combination of lectures addressing aging in both humans and animal models and hands-on-projects. They will acquire sufficient practical experience to model, design and interpret experiments and brainstorm on novel technologies and hypotheses to explore the aging of the brain using more integrative and creative approaches.

Course director

Luísa Lopes
Neurobiology of Ageing & Disease
iMM Lisboa


Cheryl Grady
The Rotman Research Institute, Baycrest,

Nora Abrous
Neurocentre Magendie INSERM U 1215,
University of Bordeaux

Keynote speakers

Hélène Amieva (Bordeaux Population Health, France)
Adam Antebi (Max Planck Institute for Biology of Ageing, Germany)
Carol Barnes (University of Arizona, USA)
Luc Buée (Centre de Recherche Jean-Pierre Aubert, France)
Gwenaëlle Catheline (Bordeaux Neurocampus, France)
Maria Llorens (Centro de Biologia Molecular Severo Ochoa, Spain)
Aline Marighetto (Bordeaux Neurocampus, France)
Lars Nyberg (Umeå University, Sweden)
Laure Rondi-Reig (Sorbonne University, France)
Yaakov Stern (Columbia University, USA)
Tony Wyss-Coray (Stanford University, USA)

More details

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Début :
lundi 20 septembre
Fin :
samedi 9 octobre
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