Neurochemistry, deep brain stimulation and Parkinson’s disease

Our research project aims to better understand the pathophysiology of Parkinson’s disease in order to improve the existing therapeutic approaches and to develop new therapies for the disease. Currently, we especially focus our work on the role of monoaminergic systems (noradrenaline, dopamine, serotonin) in the pathophysiology and therapy of Parkinson’s disease. The team is acknowledged for its neurochemical and electrophysiological inputs unraveling the mechanisms of action of the deep brain stimulation of the subthalamic nucleus and L-DOPA medication in animal models of Parkinson’s disease.