Clinical and translational exploration of sensorineural hearing loss

Genetics and Physiology of Hearing, Paris

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Fundamental questions that are essential for efficient hearing rehabilitation are addressed: how do auditory hair cells synapses and central synaptic connections evolve with aging, sound trauma and genetic neuropathies? The molecular changes occurring in auditory synaptic transmission are deciphered in mouse models. Methods of viral gene transfer are developped in order to rescue and reverse the synaptic defects.

Innovative techniques: cochlear viral gene transfer. gene editing. cochlear and hair cell electrophysiology.

Associated team from:  Institut de l’Audition – Centre de l’Institut Pasteur –  Inserm UA06

Mots clés

Selected publications

Team leader
Didier Dulon
Inserm



Team member(s)


Didier Dulon (Team leader)


Chercheurs, Praticiens hospitaliers...

Vincent Darrouzet (PU-PH)
Valérie Vidal (PU-PH)
Damien Bonnard (MCU-PH)


Ingénieur(e)s, technicien(ne)s

Yohan Bouleau
Manon Jaffredo


Post-doctorant(s)


Doctorant(s)


Adresse :
Hôpital Pellegrin Bat PQR3, 33076 Bordeaux