Bioinformatics

The bioinformatics platform provides support services for PUMA platforms and research teams to design, develop and implement IT applications and solutions for research data management.

The platform is responsible for processing and analysing data from PUMA: genotyping facility management, PCR and RNA-Seq analysis, resource management and server-based data management and storage.

With an expertise of 20 years in bioinformatics, database administration and programming, the platform offers today several services:

Transcriptomics data management and analysis

• Quantitative and droplet digital PCR, and DNA chips with GEASE web-application: monitoring of samples and plates mapping, primers validation, identification of references genes, normalization, quantification, differential expression analysis
• RNA-Seq analysis (offered with the NGS prestation): mapping, annotation, differential expression analysis, data enrichment (ontology, metabolic pathways, PCA, heatmap), statistical analysis

Genotyping and lines facility management software (ANISE):
ANISE is a complete dematerialization of an animal facility management

• Tracking and management of the wild and transgenic lines, and crossing
• Monitoring of the genotyping
• Tracking and validation of requests
• Automatic counting of ethical referrals/saisines
• Inventory and tracking of anesthetics