When a schizophrenic deficit becomes a reasoning advantage

Emmanuel Mellet, Olivier Houdé, Perrine Brazo, Bernard Mazoyer, Nathalie Tzourio-Mazoyer, Sonia Dollfus
Schizophrenia Research. 2006-06-01; 84(2-3): 359-364
DOI: 10.1016/j.schres.2006.03.024

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1. Schizophr Res. 2006 Jun;84(2-3):359-64. Epub 2006 Apr 24.

When a schizophrenic deficit becomes a reasoning advantage.

Mellet E(1), Houdé O, Brazo P, Mazoyer B, Tzourio-Mazoyer N, Dollfus S.

Author information:
(1)UMR 6194, CNRS, CEA, Université de Caen and Université Paris-Descartes
(Paris-5), France.

A deficit in context processing has been proposed to be one of the major
deficiencies in schizophrenia. A demanding reasoning task, known to promote a
very reproducible bias (i.e., a reasoning error) in healthy subjects, triggered
by a misleading context, was administered in 26 schizophrenic patients and 26
healthy participants. Responses at random were checked by including an additional
group of 11 schizophrenic patients who performed a control version of the task.
We showed that patients presented a surprising imperviousness to the reasoning
bias and had significantly better logical performances than their paired healthy
participants. This finding demonstrates that there are some problem solving
situations where disregarding contextual information, a cognitive deficit that
usually impairs schizophrenic patients gives them a cognitive advantage over
healthy controls.

DOI: 10.1016/j.schres.2006.03.024
PMID: 16632331 [Indexed for MEDLINE]

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