The IGF-1/Akt pathway is neuroprotective in Huntington’s disease and involves Huntingtin phosphorylation by Akt.

Sandrine Humbert, Elzbieta A. Bryson, Fabrice P. Cordelières, Nathan C. Connors, Sandeep R. Datta, Steven Finkbeiner, Michael E. Greenberg, Frédéric Saudou
Developmental Cell. 2002-06-01; 2(6): 831-837
DOI: 10.1016/s1534-5807(02)00188-0


Read on PubMed

---