Re-expression of locomotor function after partial spinal cord injury.

S. Rossignol, G. Barrière, O. Alluin, A. Frigon
Physiology. 2009-04-01; 24(2): 127-139
DOI: 10.1152/physiol.00042.2008

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After a complete spinal section, quadruped mammals (cats, rats, and mice) can generally regain hindlimb locomotion on a treadmill because the spinal cord below the lesion can express locomotion through a neural circuitry termed the central pattern generator (CPG). In this review, we propose that the spinal CPG also plays a crucial role in the locomotor recovery after incomplete spinal cord injury.

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