Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA.

Lucie Delemotte
Journal of General Physiology. 2018-08-24; 150(10): 1356-1359
DOI: 10.1085/jgp.201812161

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Delemotte appraises new computational work revealing that the intracellular activation gate must open for C-type inactivation to occur in K+ channels.

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