New insights on food intake control by olfactory processes: the emerging role of the endocannabinoid system.

Edgar Soria-Gomez, Luigi Bellocchio, Giovanni Marsicano
Molecular and Cellular Endocrinology. 2014-11-01; 397(1-2): 59-66
DOI: 10.1016/j.mce.2014.09.023

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1. Mol Cell Endocrinol. 2014 Nov;397(1-2):59-66. doi: 10.1016/j.mce.2014.09.023.
Epub 2014 Sep 27.

New insights on food intake control by olfactory processes: the emerging role of
the endocannabinoid system.

Soria-Gomez E(1), Bellocchio L(2), Marsicano G(3).

Author information:
(1)INSERM, U862 NeuroCentre Magendie, Endocannabinoids and Neuroadaptation,
Bordeaux, France. Electronic address: .
(2)Dept. of Biochemistry and Molecular Biology I, Sch. of Biology, Complutense
Univ. and CIBERNED, Madrid, Spain.
(3)INSERM, U862 NeuroCentre Magendie, Endocannabinoids and Neuroadaptation,
Bordeaux, France.

The internal state of the organism is an important modulator of perception and
behavior. The link between hunger, olfaction and feeding behavior is one of the
clearest examples of these connections. At the neurobiological level, olfactory
circuits are the targets of several signals (i.e. hormones and nutrients)
involved in energy balance. This indicates that olfactory areas are potential
sensors of the internal state of the organism. Thus, the aim of this manuscript
is to review the literature showing the interplay between metabolic signals in
olfactory circuits and its impact on food intake.

Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

DOI: 10.1016/j.mce.2014.09.023
PMID: 25261796 [Indexed for MEDLINE]

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