Monkey to human comparative anatomy of the frontal lobe association tracts
Cortex. 2012-01-01; 48(1): 82-96
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1. Cortex. 2012 Jan;48(1):82-96. doi: 10.1016/j.cortex.2011.10.001. Epub 2011 Oct
Monkey to human comparative anatomy of the frontal lobe association tracts.
Thiebaut de Schotten M(1), Dell’Acqua F, Valabregue R, Catani M.
(1)Natbrainlab, Department of Forensic and Neurodevelopmental Sciences, Institute
of Psychiatry, King’s College London, UK.
The greater expansion of the frontal lobes along the phylogeny scale has been
interpreted as the signature of evolutionary changes underlying higher cognitive
abilities in humans functions in humans. However, it is unknown how an increase
in number of gyri, sulci and cortical areas in the frontal lobe have coincided
with a parallel increase in connectivity. Here, using advanced tractography based
on spherical deconvolution, we produced an atlas of human frontal association
connections that we compared with axonal tracing studies of the monkey brain. We
report several similarities between human and monkey in the cingulum, uncinate,
superior longitudinal fasciculus, frontal aslant tract and orbito-polar tract.
These similarities suggest to preserved functions across anthropoids. In
addition, we found major differences in the arcuate fasciculus and the inferior
fronto-occipital fasciculus. These differences indicate possible evolutionary
changes in the connectional anatomy of the frontal lobes underlying unique human
Copyright © 2011 Elsevier Srl. All rights reserved.
PMID: 22088488 [Indexed for MEDLINE]