Laterality of neocortical slow-wave oscillations in anesthetized mice

Genki Minamisawa, Naoya Takahashi, Norio Matsuki, Yuji Ikegaya
Neuroscience Research. 2009-06-01; 64(2): 240-242
DOI: 10.1016/j.neures.2009.02.006

Read on PubMed

In the slow-wave (SW) state, the vast majority of cortical neurons exhibit mostly synchronized oscillatory activity. In this study, we examined the right-left hemispheric difference in slow-wave timings in urethane-anesthetized mice. We found that interhemispheric cross-correlograms of local field potentials (LFPs) peaked asymmetrically. Double in vivo whole-cell patch-clamp recordings also revealed the interhemispheric temporal disparity of slow wave-relevant synaptic barrages. The data suggest the hemispheric laterality in the slow wave origin.


Know more about