Intracortical Myelination of Heschl’s Gyrus and the Planum Temporale Varies With Heschl’s Duplication Pattern and Rhyming Performance: An Investigation of 440 Healthy Volunteers
Cerebral Cortex. 2018-04-18; :
DOI: 10.1093/cercor/bhy088
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Intracortical Myelination of Heschl’s Gyrus and the Planum Temporale Varies With
Heschl’s Duplication Pattern and Rhyming Performance: An Investigation of 440
Healthy Volunteers.
Tzourio-Mazoyer N(1)(2)(3), Maingault S(1)(2)(3), Panzieri J(1)(2)(3), Pepe
A(1)(2)(3), Crivello F(1)(2)(3), Mazoyer B(1)(2)(3).
Author information:
(1)University of Bordeaux, IMN, UMR 5293, F-33000 Bordeaux, France.
(2)CNRS, IMN, UMR 5293, F-33000 Bordeaux, France.
(3)CEA, GIN, IMN, UMR 5293, F-33000 Bordeaux, France.
We investigated, in 445 healthy adults whose Heschl’s gyrus (HG) gyrification
patterns had been previously identified, how an in vivo MRI marker of
intracortical myelination of HG and the planum temporale (PT) varied as a
function of HG gyrification pattern and, in cases of duplication, of anatomical
characteristics of the second HG (H2). By measuring the MRI T1/T2 ratio in
regions of interest covering the first HG (H1), H2 in cases of common stem
(H2CSD), or complete posterior duplication (H2CPD) and the PT, we showed that H1
had the highest T1/T2 values, while the PT had the lowest. The major impact of
duplication was a decrease in both H1 and PT T1/T2 values in cases of left CPD.
Concerning H2, the right and left T1/T2 values of right H2CSD were closer to
those of H1, and those of left H2CPD were closer to those of PT. After adjusting
for verbal skills, rhyming performance was not associated with T1/T2 values in
left regions, but it decreased with increasing right PT T1/T2 values. These
results reveal the existence of hemispheric differences in H2 myelination and
underline the importance of neuroimaging markers of intracortical myelination for
investigating brain structure-function relationships.
DOI: 10.1093/cercor/bhy088
PMID: 29912300