Hypersomnolence, Hypersomnia, and Mood Disorders.
Curr Psychiatry Rep. 2017-02-01; 19(2):
DOI: 10.1007/s11920-017-0763-0
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1. Curr Psychiatry Rep. 2017 Feb;19(2):13. doi: 10.1007/s11920-017-0763-0.
Hypersomnolence, Hypersomnia, and Mood Disorders.
Barateau L(1)(2)(3), Lopez R(1)(2)(3), Franchi JA(4)(5)(6), Dauvilliers
Y(7)(8)(9).
Author information:
(1)Sleep-Wake Disorders Center, Department of Neurology, Gui-de-Chauliac
Hospital, CHU Montpellier, 80 avenue Augustin Fliche, 34295, Montpellier Cedex 5,
France.
(2)National Reference Network for Narcolepsy, Montpellier, France.
(3)Inserm U1061, Montpellier, France.
(4)Services d’explorations fonctionnelles du système nerveux, Clinique du
sommeil, CHU de Bordeaux, Place Amélie Raba-Leon, 33076, Bordeaux, France.
(5)University Bordeaux, SANPSY, USR 3413, 33000, Bordeaux, France.
(6)CNRS, SANPSY, USR 3413, 33000, Bordeaux, France.
(7)Sleep-Wake Disorders Center, Department of Neurology, Gui-de-Chauliac
Hospital, CHU Montpellier, 80 avenue Augustin Fliche, 34295, Montpellier Cedex 5,
France. .
(8)National Reference Network for Narcolepsy, Montpellier, France.
.
(9)Inserm U1061, Montpellier, France. .
Relationships between symptoms of hypersomnolence, psychiatric disorders, and
hypersomnia disorders (i.e., narcolepsy and idiopathic hypersomnia) are complex
and multidirectional. Hypersomnolence is a common complaint across mood
disorders; however, patients suffering from mood disorders and hypersomnolence
rarely have objective daytime sleepiness, as assessed by the current gold
standard test, the Multiple Sleep Latency Test. An iatrogenic origin of symptoms
of hypersomnolence, and sleep apnea syndrome must be considered in a population
of psychiatric patients, often overweight and treated with sedative drugs. On the
other hand, psychiatric comorbidities, especially depression symptoms, are often
reported in patients with hypersomnia disorders, and an endogenous origin cannot
be ruled out. A great challenge for sleep specialists and psychiatrists is to
differentiate psychiatric hypersomnolence and a central hypersomnia disorder with
comorbid psychiatric symptoms. The current diagnostic tools seem to be limited in
that condition, and further research in that field is warranted.
DOI: 10.1007/s11920-017-0763-0
PMID: 28243864 [Indexed for MEDLINE]