Eyes Wide Open on AMPAR Trafficking during Motor Learning
Neuron. 2020-03-01; 105(5): 764-766
DOI: 10.1016/j.neuron.2020.02.006
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Gambino F(1), Choquet D(2).
Author information:
(1)Interdisciplinary Institute for Neuroscience, University of Bordeaux,
Bordeaux, France; Interdisciplinary Institute for Neuroscience, Centre National
de la Recherche Scientifique (CNRS) Unite Mixte de Recherche (UMR) 5297,
Bordeaux, France. Electronic address: .
(2)Interdisciplinary Institute for Neuroscience, University of Bordeaux,
Bordeaux, France; Interdisciplinary Institute for Neuroscience, Centre National
de la Recherche Scientifique (CNRS) Unite Mixte de Recherche (UMR) 5297,
Bordeaux, France; Bordeaux Imaging Center, CNRS UMS 3420, University of Bordeaux,
Institut National de la Santé et de la Recherche Médicale (INSERM) US04,
Bordeaux, France. Electronic address: .
Comment on
Neuron. 2020 Mar 4;105(5):895-908.e5.
In this issue of Neuron, Roth et al. (2020) report that the content of
GluA1-containing AMPAR at spines and dendrites in vivo in the motor and visual
cortex increases proportionally to the learning of a motor task. Visual cortex
activity is necessary for increasing AMPAR content and learning in light.
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