Determination of emotional endophenotypes: A validation of the Affective Neuroscience Personality Scales and further perspectives

Jean-Baptiste Pingault, Lydia Pouga, Julie Grèzes, Sylvie Berthoz
Psychological Assessment. 2012-06-01; 24(2): 375-385
DOI: 10.1037/a0025692

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1. Psychol Assess. 2012 Jun;24(2):375-85. doi: 10.1037/a0025692. Epub 2011 Sep

Determination of emotional endophenotypes: a validation of the Affective
Neuroscience Personality Scales and further perspectives.

Pingault JB(1), Pouga L, Grèzes J, Berthoz S.

Author information:
(1)Research Unit on Children’s Psychosocial Maladjustment, University of
Montreal, Québec, Canada.

The study of endophenotypes, notably with configured self-reports, represents a
promising research pathway to overcome the limits of a syndromal approach of
psychiatric diseases. The Affective Neuroscience Personality Scales (ANPS) is a
self-report questionnaire, based on neuroethological considerations, that could
help to assess emotional endophenotypes related to the activity in 6 core
cerebral emotional systems (FEAR, ANGER, SADNESS, CARING, PLAYFULNESS, SEEKING).
We further investigated its psychometric properties among 830 young adults and
showed that they were satisfactory. As participants also completed several other
self-reports that shared potential traits with the ANPS, we offer new validity
evidence based on relations to other variables. We also provide additional
evidence to consider that the ANPS scores can be validly interpreted for the
characterization of emotional endophenotypes involved in a variety of
psychiatric disorders. On the grounds of present results, of previous clinical
studies, as well as some preliminary neuroimaging findings, we discuss new steps
in the ANPS validation.

(c) 2012 APA, all rights reserved

DOI: 10.1037/a0025692
PMID: 21942230 [Indexed for MEDLINE]

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