Comorbidity studies of eating disorders and mood disorders. Critical review of the literature
Journal of Affective Disorders. 2007-01-01; 97(1-3): 37-49
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1. J Affect Disord. 2007 Jan;97(1-3):37-49. doi: 10.1016/j.jad.2006.06.023. Epub
2006 Aug 22.
Comorbidity studies of eating disorders and mood disorders. Critical review of
Godart NT(1), Perdereau F, Rein Z, Berthoz S, Wallier J, Jeammet P, Flament MF.
(1)Department of Psychiatry, Institut Mutualiste Montsouris (IMM), University,
René Descartes-Paris V, France.
OBJECTIVE: We conducted a critical literature review of studies assessing the
prevalence of mood disorders (MD) in subjects with eating disorders (ED;
anorexia nervosa and bulimia nervosa). In the first part of this article, we
discuss methodological issues relevant to comorbidity studies between ED and MD.
In the second part, we summarize the findings of these studies in light of the
methodological considerations raised.
METHOD: A manual computerised search (Medline) was performed for all published
studies on comorbidity between ED and MD. In order to have sufficiently
homogeneous diagnostic criteria for both categories of disorders, this search
was limited to articles published between 1985 and 2006.
RESULTS: Too few studies include control groups, few studies compared diagnostic
subgroups of ED subjects, and results are scarce or conflicting.
DISCUSSION: The results are discussed in the light of the methodological
problems observed. The implications when reviewing the results of published
studies and planning future research are set out.
PMID: 16926052 [Indexed for MEDLINE]