Chemical identity, function and regulation of enteroendocrine peptides in insects
Current Opinion in Insect Science. 2015-10-01; 11: 8-13
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Wegener C(1), Veenstra JA(2).
(1)Neurobiology and Genetics, Theodor-Boveri-Institute, Biocenter, University of
Würzburg, Würzburg, Germany. Electronic address:
(2)University of Bordeaux, INCIA UMR 5287 CNRS, Talence, France.
How animals allocate energy and metabolic decisions are coordinated is a
fundamental physiological question. Metabolic research is strongly driven by an
increasing obesity rate in humans. For insects-which contain many pest species
and disease vectors-the control of feeding is of agroeconomical and medical
importance. Regulatory peptides have since long been in focus of metabolic
research. In insects, major advances have been made recently, mostly due to
research in the genetically tractable Drosophila melanogaster with focus on the
central nervous system as a source of neuropeptides. Research on peptides
produced by enteroendocrine cells remained peripheral, but this situation is
about to change. This review highlights current knowledge and advances on the
identity and role of enteroendocrine insect peptides.
Copyright © 2015 Elsevier Inc. All rights reserved.