Association between prism adaptation and auditory cues on spatial navigation in individuals with unilateral neglect
Annals of Physical and Rehabilitation Medicine. 2020-01-01; 63(1): 12-20
DOI: 10.1016/j.rehab.2019.03.005
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Cogné M(1), Guillaud E(2), Guillot L(3), Klinger E(4), Glize B(5), Jacquin-Courtois S(6), Cazalets JR(7), Joseph PA(8).
Author information:
(1)Rehabilitation unit, University hospital of Bordeaux, 33076 Bordeaux, France;
EA4136, Bordeaux University, 33076 Bordeaux, France; Service de médecine physique
et de réadaptation, rehabilitation unit, university hospital of Rennes, 35000
Rennes, France. Electronic address: .
(2)Incia, UMR CNRS Bordeaux University, 33000 Bordeaux, France. Electronic
address: .
(3)EA4136, Bordeaux University, 33076 Bordeaux, France. Electronic address:
.
(4)ESIEA, Digital Interactions Health and Disability Lab, 53000 Laval, France;
French Institute for Research on Handicap (IFRH), 75651 Paris , France.
Electronic address: .
(5)Rehabilitation unit, University hospital of Bordeaux, 33076 Bordeaux, France;
EA4136, Bordeaux University, 33076 Bordeaux, France. Electronic address:
.
(6)Inserm UMR-S 864, Espace et action, rehabilitation medicine unit, university
hospital of Lyon, 16, avenue Lépine, 69676 Bron, France. Electronic address:
.
(7)Incia, UMR CNRS Bordeaux University, 33000 Bordeaux, France. Electronic
address: .
(8)Rehabilitation unit, University hospital of Bordeaux, 33076 Bordeaux, France;
EA4136, Bordeaux University, 33076 Bordeaux, France; French Institute for
Research on Handicap (IFRH), 75651 Paris , France. Electronic address:
.
BACKGROUND: Unilateral neglect is common among right-hemispheric stroke
individuals and also concerns the auditory modality. Prism adaptation can improve
auditory extinction during a dichotic listening task, but its effect during an
ecological task has not been studied.
OBJECTIVE: The main objective was to evaluate whether lateralized cueing before
and after prism adaptation improved virtual spatial navigation of stroke
individuals with visual and auditory unilateral neglect. Secondary objectives
were to assess spatial memory and obtain a better understanding of the mechanism
of the cueing treatment by using an eye-tracker.
METHODS: We included 22 stroke individuals with left visual and auditory neglect,
14 individuals without neglect, and 12 healthy controls. After a familiarization
task, participants underwent 3 evaluation sessions. Participants were first
passively shown a path that they had then to actively reproduce by using a
joystick. A path with lateralized beeping sounds indicating direction and a path
without any sounds were followed in a randomized order. After prism adaptation,
the participants followed a third path with lateralized beeping sounds. The time
of navigation and number of trajectory mistakes were recorded. After navigation,
spatial memory was assessed. Additionally, an eye-tracker was used during the
navigation period.
RESULTS: The navigational performance of participants with neglect was
significantly better with than without auditory cues, especially after prism
adaptation. With auditory cues, participants without neglect reached the
navigational performance of healthy controls. The spatial memory of individuals
with neglect was significantly lower with auditory cues. Eye-tracking analyses
showed that participants with neglect made more saccades and looked longer at the
right-square angles in the absence of auditory cues.
CONCLUSIONS: This study demonstrates the positive effect of auditory cues in
virtual spatial navigation of individuals with visual and auditory neglect and
the potentiation of the help of cues after prism adaptation.
Copyright © 2019 Elsevier Masson SAS. All rights reserved.