Validation of the French version of the MSA health-related Quality of Life scale (MSA-QoL)
Revue Neurologique. 2013-01-01; 169(1): 53-58
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1. Rev Neurol (Paris). 2013 Jan;169(1):53-8. doi: 10.1016/j.neurol.2012.02.011. Epub
2012 Jun 6.
Validation of the French version of the MSA health-related Quality of Life scale
Meissner WG(1), Foubert-Samier A, Dupouy S, Debs R, Gerdelat-Mas A, Cochen De
Cock V, Schrag A, Rascol O, Tison F, Pavy-Le Traon A.
(1)Service de neurologie, centre de référence atrophie multisystématisée, centre
de reference AMS, hôpital du Haut-Lévêque, CHU de Bordeaux, avenue Magellan,
33604 Pessac cedex, France. *protected email*
INTRODUCTION: Multiple system atrophy (MSA) has considerable impact on
health-related quality of life. The MSA health-related Quality of Life scale
(MSA-QoL) is a patient-reported questionnaire, which has been recently designed
to evaluate the quality of life in MSA. The objective of the present study was to
validate the French version of the MSA-QoL questionnaire.
METHODS: One hundred and thirty-six consecutive MSA patients were included in the
study. Four patients with more than 10% missing responses were excluded from the
final analysis. Data quality, scaling assumptions, acceptability, reliability and
validity were assessed similar to the original validation of the English version.
RESULTS: Missing responses were low, item and subscale scores were evenly
distributed and floor and ceiling effects were negligible. Item-total
correlations were higher than the recommended greater than 0.30 and internal
consistency was high for all subscales. Test-retest reliability was good for all
subscales. Validity was supported by moderate interscale correlations between the
subscales and the predicted correlations with other scales assessing motor
disability, activities of daily living, quality of life and mood.
DISCUSSION: The French version of the MSA-QoL displays robust psychometric
properties similar to the English version.
CONCLUSION: The French version of MSA-QoL seems suitable for assessing quality of
life in French speaking MSA patients.
Copyright © 2012 Elsevier Masson SAS. All rights reserved.
PMID: 22682047 [Indexed for MEDLINE]