To stress or not to stress: a question of models

J. Megan Gray, Francis Chaouloff, Matthew N. Hill
Current Protocols in Neuroscience. 2015-01-01; 70(1):
DOI: 10.1002/0471142301.ns0833s70

PubMed
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Stress research is a rapidly evolving field that encompasses numerous disciplines
ranging from neuroscience to metabolism. With many new researchers migrating into
the field, navigating the hows and whys of specific research questions can
sometimes be enigmatic given the availability of so many models in the stress
field. Additionally, as with every field, there are many seemingly minor
experimental details that can have dramatic influences on data interpretation,
although many of these are unknown to those not familiar with the field. The aim
of this overview is to provide some suggestions and points to guide researchers
moving into the stress field and highlight relevant methodological points that
they should consider when choosing a model for stress and deciding how to
structure a study. We briefly provide a primer on the basics of endpoint
measurements in the stress field, factors to consider when choosing a model for
acute stress, the difference between repeated and chronic stress, and
importantly, influencing variables that modulate endpoints of analysis in stress
work.

Copyright © 2015 John Wiley & Sons, Inc.

 

Auteurs Bordeaux Neurocampus