[Epub ahead

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Time-Course of Nigrostriatal Degeneration in a Progressive MPTP-Lesioned Macaque Model of Parkinson’s Disease

Wassilios Meissner, Caroline Prunier, Denis Guilloteau, Sylvie Chalon, Christian E. Gross, Erwan Bezard
MN. 2003-01-01; 28(3): 209-218
DOI: 10.1385/MN:28:3:209

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of print]

Distribution of heavy metals and associated human health risk in mine,
agricultural and roadside soils at the largest chromite mine of India.

Naz A(1)(2), Chowdhury A(3)(4), Mishra BK(2), Karthikeyan K(1).

Author information:
(1)Environmental Laboratory Division, Gujarat Institute of Desert Ecology, P.O.
83, Mundra Road, Bhuj, Gujarat, 370001, India.
(2)Department of Environmental Science and Engineering, Indian Institute of
Technology (Indian School of Mines), Dhanbad, Jharkhand, 826004, India.
(3)Department of Environmental Science and Engineering, Indian Institute of
Technology (Indian School of Mines), Dhanbad, Jharkhand, 826004, India.
.
(4)Coastal and Marine Ecology Division, Gujarat Institute of Desert Ecology, P.O.
83, Mundra Road, Bhuj, Gujarat, 370001, India. .

This study accessed the levels of Cd, Cr, Fe, Mn, Ni, Pb and Zn concentration in
soils of different locations (mine, roadside, agricultural and control sites) of
Sukinda chromite mine (the India’s largest Chromite mine and listed among the
world’s ten most polluted regions). Geo-accumulation (Igeo) index indicates that
the mine, agricultural and roadside soils are ‘heavily to extremely contaminated’
due to Cr, Ni, Pb and Cd, hence human residing/working in this region can have
health hazards due to contaminated soil via different exposure pathways. The
concentration of heavy metals (mg/kg) in mine site vary between 52.35 and 244.8
(Cr6+), 12,030.2 and 31,818.6 (Cr3+), 5460.4 and 8866.0 (Ni), 70.02 and 208.6
(Pb), 0.95 and 5.3 (Cd), 209.1 and 360.4 (Mn), 21,531.8 and 28,847 (Fe) and 221
and 349.3 (Zn). Fe, Cr6+, Cr3+ and Ni concentration in soil follows an order of
mine site > road sites > agricultural lands > control forest sites. Principal
component analysis and hierarchical cluster analysis indicate Cd, Cr, Fe, Ni and
Pb as major pollutants in the region. Cancer Risk is ‘high’ in both adult
(5.38E-04) and children (4.45E-04) in mining sites and ‘low’ to ‘very low’ in
agricultural and road side soils. The hazard index for all the heavy metals in a
mining areas is varied from 2.9 to 5.2 in adult and 2.8-5.1 in children,
indicating ‘high’ to ‘very high’ non-cancer risk due to significant contribution
of Ni, Pb and Cr6+ concentration (73, 11 and 10%, respectively).

DOI: 10.1007/s10653-018-0090-3
PMID: 29582262

Auteurs Bordeaux Neurocampus