The Soothing Touch: Microglial Contact Influences Neuronal Excitability
Developmental Cell. 2012-12-01; 23(6): 1125-1126
DOI: 10.1016/j.devcel.2012.11.015
1. Dev Cell. 2012 Dec 11;23(6):1125-6. doi: 10.1016/j.devcel.2012.11.015.
The soothing touch: microglial contact influences neuronal excitability.
Panatier A(1), Robitaille R.
Author information:
(1)INSERM U862, Neurocentre Magendie, 33077 Bordeaux, France; Université de
Bordeaux, 33077 Bordeaux, France.
Comment on
Dev Cell. 2012 Dec 11;23(6):1189-202. doi: 10.1016/j.devcel.2012.10.027.
Resting microglial cells in the brain scan their environment with their
processes, primed to react to injury and disease. In this issue of Developmental
Cell, Li and colleagues (2012) report that resting microglia also react to
physiological neuronal activity, sending their processes toward highly active
neurons to regulate their excitability.
Copyright © 2012 Elsevier Inc. All rights reserved.
DOI: 10.1016/j.devcel.2012.11.015
PMID: 23237948