The Collaborative Cross, a community resource for the genetic analysis of complex traits
1. Nat Genet. 2004 Nov;36(11):1133-7.
The Collaborative Cross, a community resource for the genetic analysis of complex
traits.
Churchill GA(1), Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD,
Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ,
Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD,
Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J,
Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G,
Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA,
Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G,
Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR,
Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman
G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH,
Nagase H, Nowakowski RS, O’Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K,
Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi
Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K,
Shou S, Sillanpää MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino
LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams
RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F; Complex Trait Consortium.
Author information:
(1)The Jackson Laboratory, 600 Main Street Bar Harbor, Maine 04609, USA.
The goal of the Complex Trait Consortium is to promote the development of
resources that can be used to understand, treat and ultimately prevent pervasive
human diseases. Existing and proposed mouse resources that are optimized to study
the actions of isolated genetic loci on a fixed background are less effective for
studying intact polygenic networks and interactions among genes, environments,
pathogens and other factors. The Collaborative Cross will provide a common
reference panel specifically designed for the integrative analysis of complex
systems and will change the way we approach human health and disease.
DOI: 10.1038/ng1104-1133
PMID: 15514660 [Indexed for MEDLINE]