Sensitive liposomes encoded with oligonucleotide amphiphiles: a biocompatible switch.
Chem. Commun.. 2008-01-01; (43): 5550
DOI: 10.1039/b812398e
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1. Chem Commun (Camb). 2008 Nov 21;(43):5550-2. doi: 10.1039/b812398e. Epub 2008 Sep
23.
Sensitive liposomes encoded with oligonucleotide amphiphiles: a biocompatible
switch.
Gissot A(1), Di Primo C, Bestel I, Giannone G, Chapuis H, Barthélémy P.
Author information:
(1)Université de Bordeaux, 33076 Bordeaux Cedex, France.
DNA-tagged liposomes made of DOPC specifically bind to a fluorescently labelled
complementary ss-DNA with virtually no influence from the lipid bilayer despite
the absence of a linker; depending on an external stimulus, either physical
(temperature) or chemical (competitive complementary ON sequences), the liposomes
switch between an on and off fluorescent state depending on the location of the
probe either at the surface or in the bulk.
DOI: 10.1039/b812398e
PMID: 18997948 [Indexed for MEDLINE]